Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/06/03 15:20:28」(JST)

wiki en

Rachischisis (Greek: "rhachis - ῥάχις" - spine, and "schisis - σχίσις" - split) is a developmental birth defect involving the neural tube. This anomaly occurs in utero, when the posterior neuropore of the neural tube fails to close by the 27th intrauterine day. As a consequence the vertebrae overlying the open portion of the spinal cord do not fully form and remain unfused and open, leaving the spinal cord exposed. Patients with rachischisis have motor and sensory deficits, chronic infections, and disturbances in bladder function. This defect often occurs with anencephaly.

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 無脳症 anencephaly
2. 神経管欠損症の超音波診断 ultrasound diagnosis of neural tube defects

English Journal

Drinking water treatment is not associated with an observed increase in neural tube defects in mice.

Melin VE1, Johnstone DW, Etzkorn FA, Hrubec TC.
Environmental monitoring and assessment.Environ Monit Assess.2014 Jun;186(6):3717-24. doi: 10.1007/s10661-014-3652-6. Epub 2014 Feb 5.
Disinfection by-products (DBPs) arise when natural organic matter in source water reacts with disinfectants used in the water treatment process. Studies have suggested an association between DBPs and birth defects. Neural tube defects (NTDs) in embryos of untreated control mice were first observed i
PMID 24497082

An association study between SUFU gene polymorphisms and neural tube defects.

Lu X1, Wang Z, Wang J, Shangguan S, Bao Y, Lu P, Wang L.
The International journal of neuroscience.Int J Neurosci.2014 Jun;124(6):436-42. doi: 10.3109/00207454.2013.849249. Epub 2013 Nov 7.
Neural tube defects (NTDs) in mammals are rooted in aberrant neural tube closure during early embryogenesis, which is caused by multiple environmental and genetic factors. The Sonic Hedgehog pathway is involved in the induction of the floor plate and participates in formation of the neural tube. Mut
PMID 24070372

Impaired one carbon metabolism and DNA methylation in alcohol toxicity.

Kruman II1, Fowler AK.
Journal of neurochemistry.J Neurochem.2014 Jun;129(5):770-80. doi: 10.1111/jnc.12677. Epub 2014 Mar 7.
Excessive alcohol consumption is a prominent problem and one of the major causes of mortality and morbidity around the world. Long-term, heavy alcohol consumption is associated with a number of deleterious health consequences, such as cancer, heart and liver disease, a variety of neurological, cogni
PMID 24521073

Japanese Journal

Prenatal Neuroimagings in Fetal Dysraphism

OI Shizuo,TAMAKI Norihiko,MATSUMOTO Satoshi,KATAYAMA Kazuaki,MOCHIZUKI Matsuto
Ｎｅｕｒｏｓｏｎｏｌｏｇｙ：　神経超音波医学 3(2), 90-96, 1990
… Cephaloschisis, in one craniorachischisis and four anencephaly, was satisfactorily diagnosed in ultrasonographic configuration of the absent calvaria and high intensity shadow of exposed placode of MR TI weighted images. …
NAID 130001742733