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Curcumin Ameliorates Lead (Pb(2+))-Induced Hemato-Biochemical Alterations and Renal Oxidative Damage in a Rat Model.

Abdel-Moneim AM1,2, El-Toweissy MY3,4, Ali AM3, Awad Allah AA5, Darwish HS5, Sadek IA3.
Biological trace element research.Biol Trace Elem Res.2015 Nov;168(1):206-20. doi: 10.1007/s12011-015-0360-1. Epub 2015 May 7.
This study aims to evaluate the protective role of curcumin (Curc) against hematological and biochemical changes, as well as renal pathologies induced by lead acetate [Pb (CH3COO)2·3H2O] treatment. Male albino rats were intraperitoneally treated with Pb(2+) (25 mg of lead acetate/kg b.w., once a d
PMID 25947936

Development of CYP11B1 and CYP11B2 assays utilizing homogenates of adrenal glands: Utility of monkey as a surrogate for human.

Cerny MA1, Csengery A2, Schmenk J2, Frederick K2.
The Journal of steroid biochemistry and molecular biology.J Steroid Biochem Mol Biol.2015 Nov;154:197-205. doi: 10.1016/j.jsbmb.2015.08.004. Epub 2015 Aug 21.
Elevated levels of aldosterone are associated with arterial hypertension, congestive heart failure, chronic kidney disease, and obesity. Aldosterone is produced predominantly in the zona glomerulosa of the cortex of the adrenal gland by the enzyme aldosterone synthase (CYP11B2). Treatment of the abo
PMID 26303746

Heat shock protein 72 (Hsp72) specific induction and temporal stability in urine samples as a reliable biomarker of acute kidney injury (AKI).

Ortega-Trejo JA1,2, Pérez-Villalva R1,2, Barrera-Chimal J1,2, Carrillo-Pérez DL2, Morales-Buenrostro LE2, Gamba G1,2, Flores ME1, Bobadilla NA1,2.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.Biomarkers.2015 Oct 21:1-7. [Epub ahead of print]
We demonstrated that urinary heat shock protein of 72 KDa (Hsp72) is a sensitive biomarker for the early detection of acute kidney injury (AKI). However, whether Hsp72 induction during an AKI episode is kidney-specific is unknown, as well as, the degree of Hsp72 stability in urine samples. In rats t
PMID 26488549

栗原昭三,保田幹男
日本獸醫學雜誌 35(4), 311-318_2, 1973-08-25
… The kidneys of the fowl are divided into three Robes, Lobus renaalis cranialis,Lobus renalis medius, and Lobus renalis caudalis. … The portionts of tlae lobtule correspond-ing to Cortex renis and Medulla renis of tlae mammalian kidney were named Acinus?corticalis and Acinus medullaris, respectively. …
NAID 110003981190