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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2017/08/13 11:43:57」(JST)
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Micrograph of
corpora amylacea in benign prostatic glands. H&E stain.
Natural luminescence of corpora amylacea in the lumen of the prostate in ultraviolet light
Corpora amylacea (CA) are small hyaline masses of unknown significance found in the prostate gland,[1] neuroglia,[2] and pulmonary alveoli.[1] They are derived from degenerate cells or thickened secretions and occur more frequently with advancing age, and are particularly profuse in neurodegenerative diseases.[1] While their significance is unknown, they can be used to identify these organs microscopically. A report published in 2017 suggests a role of debris clearance for the CA.[1] This was described in an earlier report as a debris disposal system.[3]
In the brain, corpora amylacea are contained in foot processes of astrocytes and are usually present in sub-pial location and around blood vessels.[citation needed] In comparison to prostatic corpora amylacea, these are only faintly laminar and less eosinophilic. The major constituent has been shown to be amyloid in humans[1] and the CA in other species are known as polyglucosan bodies.[3] These bodies have no known pathologic correlation[citation needed] and can be confused with fungal yeast forms such as cryptococcus[citation needed].
In the prostate, where they are also known as prostatic concretions, they usually appear in benign glands; however, their presence cannot be used to exclude cancer.[4]
References
- ^ a b c d e Röcken, C. (Oct 1966). "Corpora amylacea in the lung, prostate and uterus. A comparative and immunohistochemical study". Pathology, Research and Practice. pp. 998–1006. doi:10.1016/S0344-0338(96)80041-0.
- ^ Augé, Elisabet; et al. (3 February 2017). "New perspectives on corpora amylacea in the human brain". Scientific Reports. doi:10.1038/srep41807. Retrieved 3 August 2017.
- ^ a b Cavanagh, J. B (1 April 1999). "Corpora-amylacea and the family of polyglucosan diseases". Brain Research Reviews. pp. 265–295. doi:10.1016/S0165-0173(99)00003-X.
- ^ Christian JD, Lamm TC, Morrow JF, Bostwick DG (January 2005). "Corpora amylacea in adenocarcinoma of the prostate: incidence and histology within needle core biopsies". Mod. Pathol. 18 (1): 36–9. PMID 15309020. doi:10.1038/modpathol.3800250.
UpToDate Contents
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English Journal
- Periodic acid-Schiff granules in the brain of aged mice: From amyloid aggregates to degenerative structures containing neo-epitopes.
- Manich G1, Cabezón I1, Augé E1, Pelegrí C2, Vilaplana J3.
- Ageing research reviews.Ageing Res Rev.2016 Mar 9;27:42-55. doi: 10.1016/j.arr.2016.03.001. [Epub ahead of print]
- Brain ageing in mice leads to the progressive appearance and expansion of degenerative granular structures frequently referred as "PAS granules" because of their positive staining with periodic acid-Schiff (PAS). PAS granules are present mainly in the hippocampus, although they have also been descri
- PMID 26970374
- The small leucine rich proteoglycan fibromodulin is overexpressed in human prostate epithelial cancer cell lines in culture and human prostate cancer tissue.
- Reyes N1,2, Benedetti I1, Bettin A1,2, Rebollo J1,2, Geliebter J3.
- Cancer biomarkers : section A of Disease markers.Cancer Biomark.2016 Jan 18;16(1):191-202. doi: 10.3233/CBM-150555.
- BACKGROUND: Fibromodulin is a small leucine-rich proteoglycan important for extracellular matrix organization and essential for tissue repair in multiple organs. The main function of this proteoglycan is the regulation of collagen fibrillogenesis; however, more recently described roles for fibromodu
- PMID 26600400
- Hypersialylation is a common feature of neurofibrillary tangles and granulovacuolar degenerations in Alzheimer's disease and tauopathy brains.
- Nagamine S1, Yamazaki T2, Makioka K1, Fujita Y1, Ikeda M1, Takatama M3, Okamoto K3, Yokoo H4, Ikeda Y1.
- Neuropathology : official journal of the Japanese Society of Neuropathology.Neuropathology.2015 Dec 21. doi: 10.1111/neup.12277. [Epub ahead of print]
- Glycosylation is one of the major post-translational modifications of proteins. The status of sialylation of the neuropathological hallmarks of various neurodegenerative disorders was investigated in this study. Here, we report the novel findings that two phosphorylated tau (p-tau)-containing struct
- PMID 26685795
Japanese Journal
- アストロサイト障害の組織学的指標としてのcorpora amylacea貪食像:視神経脊髄炎剖検例9例における検討
- Localization of blood proteins thrombospondin1 and ADAMTS13 to cerebral corpora amylacea
- Neuropathology : official journal the Japanese Society of Neuropathology 29(6), 664-671, 2009-12-01
- NAID 10028192660
- Affinity of corpora amylacea for oligonucleotides : Sequence dependency and proteinaceous binding motif
- Neuropathology : official journal the Japanese Society of Neuropathology 26(4), 277-282, 2006-08-01
- NAID 10018058867
Related Links
- Definition of corpora amylacea in the Medical Dictionary. corpora amylacea explanation. Information about corpora amylacea in Free online English dictionary. What is corpora amylacea? Meaning of corpora amylacea medical ...
- Corpora amylacea are large, round to oval glycoprotein structures that are found within alveoli in a variety of circumstances. They have been reported to be present in up to about 4% of autopsy lungs and are incidental findings with no ...
Related Pictures
★リンクテーブル★
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- 英
- amylaceous bodies amylaceous corpuscles, amyloid bodies(corpuscles)
- ラ
- corpora amylacea
- 同
- 澱粉様小体、類澱粉小体、類デンプン小体、コロイド小体 colloid corpuscles
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体
- 関
- body、corpus