WordNet

membranous tissue covering internal organs and other internal surfaces of the body (同)epithelial_tissue
the transparent dome-shaped anterior portion of the outer covering of the eye; it covers the iris and pupil and is continuous with the sclera
of or related to the cornea

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上皮[組織](生物体の表皮・血管内壁など)
(眼球の)角膜
角膜の

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/01/10 16:10:41」(JST)

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The corneal epithelium (epithelium corneæ anterior layer) is made up of epithelial tissue and covers the front of the cornea. It acts as a barrier to protect the cornea, resisting the free flow of fluids from the tears, and prevents bacteria from entering the epithelium and corneal stroma.

The corneal epithelium consists of several layers of cells. The cells of the deepest layer are columnar, known as basal cells. Then follow two or three layers of polyhedral cells, commonly known as wing cells. The majority of these are prickle cells, similar to those found in the stratum mucosum of the cuticle. Lastly, there are three or four layers of squamous cells, with flattened nuclei. The layers of the epithelium are constantly undergoing mitosis. Basal and wing cells migrate to the anterior of the cornea, while squamous cells age and slough off into the tear film.

Cornea cell LASIK complication

Epithelial ingrowth is a LASIK complication in which cells from the cornea surface layer (epithelial cells) begin to grow underneath the corneal flap. Epithelial ingrowth is a rarely occurring LASIK complication, appearing in less than one percent of LASIK procedures.^{[citation needed]} However, the incidence of epithelial ingrowth appears to be higher after subsequent enhancement LASIK procedures.^{[citation needed]} This complication is not present in PRK or other non-flap vision correction procedures.

Disorders

Recurrent corneal erosion

External links

Epithelium Ingrowth After LASIK

UpToDate Contents

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1. コンタクトレンズの合併症 complications of contact lenses
2. 角膜剥離および角膜異物 corneal abrasions and corneal foreign bodies
3. 単純ヘルペス性角膜炎 herpes simplex keratitis
4. 原発性乳児緑内障 primary infantile glaucoma
5. 光線角膜炎 photokeratitis

English Journal

The influence of substrate topography on the migration of corneal epithelial wound borders.

Yanez-Soto B, Liliensiek SJ, Gasiorowski JZ, Murphy CJ, Nealey PF.SourceDepartment of Chemical and Biological Engineering, School of Engineering, University of Wisconsin-Madison, Madison, WI 53706, USA. Electronic address: yanezsoto@ucdavis.edu.
Biomaterials.Biomaterials.2013 Dec;34(37):9244-51. doi: 10.1016/j.biomaterials.2013.08.042. Epub 2013 Sep 7.
Currently available artificial corneas can develop post-implant complications including epithelial downgrowth, infection, and stromal melting. The likelihood of developing these disastrous complications could be minimized through improved formation and maintenance of a healthy epithelium covering th
PMID 24016856

Corneal regeneration by transplantation of corneal epithelial cell sheets fabricated with automated cell culture system in rabbit model.

Kobayashi T, Kan K, Nishida K, Yamato M, Okano T.SourceCentral Research Laboratory, Hitachi, Ltd., 2520 Akanuma, Hiki-gun, Hatoyama-machi, Saitama 350-0395, Japan; Institute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, TWIns, 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan.
Biomaterials.Biomaterials.2013 Dec;34(36):9010-7. doi: 10.1016/j.biomaterials.2013.07.065. Epub 2013 Aug 23.
We have performed clinical applications of cell sheet-based regenerative medicine with human patients in several fields. In order to achieve the mass production of transplantable cell sheets, we have developed automated cell culture systems. Here, we report an automated robotic system utilizing a ce
PMID 23978517

The cellular mechanisms of dry eye: From pathogenesis to treatment.

Mantelli F, Massaro-Giordano M, Macchi I, Lambiase A, Bonini S.SourceIRCCS Fondazione GB Bietti of Rome, Rome, Italy.
Journal of cellular physiology.J Cell Physiol.2013 Dec;228(12):2253-6. doi: 10.1002/jcp.24398.
Dry eye is a complex disease characterized by changes in the ocular surface epithelia related to reduced quality and/or quantity of tears, inflammatory reaction, and impairment of ocular surface sensitivity. It has recently been proposed that increased tear osmolarity represents a main trigger to th
PMID 23696296

Japanese Journal

ラット角膜上皮剝離モデルを用いた種々市販緑内障治療配合剤の角膜傷害性評価

長井紀章,吉岡千晶,森愛里 [他]
あたらしい眼科 32(3), 419-424, 2015-03
NAID 40020415252

ヒト重層化培養角膜上皮モデルを用いた眼科用製剤の眼刺激性に関する新規評価手法の開発

髙田洋平,櫻井俊輔,宮本幸治 [他]
あたらしい眼科 31(3), 409-413, 2014-03
NAID 40020035685

From stem cell niche environments to engineering of corneal epithelium tissue

Tsai Ray Jui-Fang,Tsai Ryan Yao-Nien
Japanese journal of ophthalmology : the official international journal of the Japanese Ophthalmological Society 58(2), 111-119, 2014-03
NAID 40020019712

Related Pictures

★リンクテーブル★

リンク元	「角膜上皮」「corneal epithelia」
拡張検索	「anterior corneal epithelium」
関連記事	「corneal」

「角膜上皮」

Corneal epithelium
	Vertical section of human cornea from near the margin. (Waldeyer.) Magnified. 1. Epithelium.; 2. Anterior elastic lamina.; 3. substantia propria.; 4. Posterior elastic lamina.; 5. Endothelium of the anterior chamber.; a. Oblique fibers in the anterior layer of the substantia propria.; b. Lamellæ the fibers of which are cut across, producing a dotted appearance.; c. Corneal corpuscles appearing fusiform in section.; d. Lamellæ the fibers of which are cut longitudinally.; e. Transition to the sclera, with more distinct fibrillation, and surmounted by a thicker epithelium.; f. Small blood vessels cut across near the margin of the cornea.
Details
Latin	Epithelium anterius corneae
Identifiers
Gray's	p.1007
MeSH	A09.371.060.217.325
Dorlands; /Elsevier	e_13/12339086
TA	A15.2.02.018
FMA	FMA:58263
	Anatomical terminology