WordNet

(genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors" (同)cistron, factor
of words or propositions so related that each is the negation of the other; "`male and `female are complementary terms"
informal term for information; "give me the gen on your new line of computers"

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1. 遺伝学およびゲノミクスのためのツール：遺伝子発現プロファイリング tools for genetics and genomics gene expression profiling
2. 脊髄小脳変性症 the spinocerebellar ataxias
3. 原発性免疫不全症に対する遺伝子治療 gene therapy for primary immunodeficiency
4. 肥満の病因 pathogenesis of obesity
5. 大腸癌の分子遺伝学 molecular genetics of colorectal cancer

Gold nanoparticles-decorated graphene field-effect transistor biosensor for femtomolar MicroRNA detection.

Cai B1, Huang L2, Zhang H3, Sun Z1, Zhang Z4, Zhang GJ5.
Biosensors & bioelectronics.Biosens Bioelectron.2015 Dec 15;74:329-34. doi: 10.1016/j.bios.2015.06.068. Epub 2015 Jun 30.
Early detection is proven to be the best chance for successful cancer treatment. MiRNAs, as ideal biomarkers, can identify cancer in the early stage. Therefore, development of highly sensitive and selective detection methods for miRNA is still anticipated. Here we report on a gold nanoparticles (AuN
PMID 26159152

IFN-λ gene polymorphisms as predictive factors in chronic hepatitis C treatment-naive patients without access to protease inhibitors.

Olmedo DB1, Cader SA1, Porto LC1.
Journal of medical virology.J Med Virol.2015 Oct;87(10):1702-15. doi: 10.1002/jmv.24227. Epub 2015 May 12.
The single nucleotides polymorphisms analyses in the regions near the IL28B gene in patients chronically infected with genotype 1 hepatitis C virus (HCV) are an important predictive factor for sustained virological response (SVR). The aim was to assess the predictive value of the polymorphisms of th
PMID 25970604

Identification, Phylogeny, and Function of fabp2 Paralogs in Two Non-Model Teleost Fish Species.

Kaitetzidou E1, Chatzifotis S, Antonopoulou E, Sarropoulou E.
Marine biotechnology (New York, N.Y.).Mar Biotechnol (NY).2015 Oct;17(5):663-77. doi: 10.1007/s10126-015-9648-6. Epub 2015 Aug 14.
Intestinal fatty-acid-binding protein (IFABP or FABP2) is a cytosolic transporter of long-chain fatty acids, which is mainly expressed in cells of intestinal tissue. Fatty acids in teleosts are an important source of energy for growth, reproduction, and swimming and a main ingredient in the yolk sac
PMID 26272429

A novel myogenic function residing in the 5′ non-coding region of Insulin receptor substrate-1 (Irs-1) transcript

Nagano Hikaru,Yamagishi Naoko,Tomida Chisato,Yano Chiaki,Aibara Kana,Kohno Shohei,Abe Tomoki,Ohno Ayako,Hirasaka Katsuya,Okumura Yuushi,Mills Edward M,Nikawa Takeshi,Teshima-Kondo Shigetada
BMC Cell Biology 16(1), 8, 2015-03-11
… Results: In this study, we identified a novel bifunctional RNA that is transcribed from insulin receptor substrate-1 (Irs-1) gene with full-length 5'UTR sequence (FL-Irs-1 mRNA). … The FL-Irs-1 5'UTR contains a partial complementary sequence to Rb mRNA, which is a critical factor for myogenic differentiation. … The overexpression of the 5'UTR markedly reduced Rb mRNA expression, and this reduction was fully dependent on the complementary element and was not compensated by IRS-1 protein. …
NAID 120005602600

菱川朋人,平松匡文,徳永浩司,杉生憲志,伊達勲
脳神経外科ジャーナル 24(4), 239-243, 2015
もやもや病の病態解析において血管構築と遺伝子の観点から最新の知見を紹介する. 血管構築においては前方循環と外頚動脈系, 前方循環と後方循環の間にそれぞれinteractionが存在する. 前者のinteractionは「鈴木の分類」に代表され, 病態解析の中心的役割を担ってきた. 後者のinteractionは虚血重症化に関与し, 小児と成人で異なるパターンが存在する. 遺伝的要因においてはRN …
NAID 130005066023

神内伸也,西川祐未,岡邑香里 [他],岩田直洋,臼井達洋,岡﨑真理,松崎広和,宮野義之,飯塚博,浅野哲,日比野康英
日本補完代替医療学会誌 12(1), 19-27, 2015
目的：霊芝菌糸体培養培地抽出物 (WER) の血糖上昇抑制作用を明らかにするために，ラット骨格筋由来培養細胞（L6 細胞）を用いて，糖輸送体 4 (GLUT4) の膜移行と糖取り込み，さらに，このプロセスに関与する細胞内シグナル伝達系を検討した．方法：WER 処理後，細胞内 GLUT4 を蛍光免疫染色法およびウエスタンブロット法により，さらにグルコースの細胞内取り込み量を解析した．また，細胞内シグ …
NAID 130005063808