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English Journal

Trophic stimulation of articular chondrocytes by late-passage mesenchymal stem cells in coculture.

Wang M, Rahnama R, Cheng T, Grotkopp E, Jacobs L, Limburg S, Kim HT, Kuo AC.SourceDepartment of Orthopaedic Surgery, University of California, San Francisco, CA.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society.J Orthop Res.2013 Dec;31(12):1936-42. doi: 10.1002/jor.22466. Epub 2013 Aug 29.
Coculture of mesenchymal stem cells (MSCs) with articular chondrocytes (ACs) increases glycosaminoglycan (GAG) accumulation compared to monoculture. MSCs might (1) differentiate into ACs (progenitor role) and/or (2) stimulate AC matrix metabolism (trophic role). MSCs lose the ability to undergo chon
PMID 24038580

κ-carrageenan induces the disruption of intestinal epithelial Caco-2 monolayers by promoting the interaction between intestinal epithelial cells and immune cells.

Jiang HY, Wang F, Chen HM, Yan XJ.SourceKey Laboratory of Applied Marine Biotechnology, Ministry of Education, Ningbo University, Ningbo, Zhejiang 315211, P.R. China.
Molecular medicine reports.Mol Med Rep.2013 Dec;8(6):1635-42. doi: 10.3892/mmr.2013.1726. Epub 2013 Oct 14.
κ‑carrageenan (κ‑CGN) is an important food additive that has been demonstrated to induce colitis in animal models. In the present study, the effects of κ‑CGN were assessed using an in vitro co‑culture system that contained intestinal epithelial Caco‑2 cells and activated macrophage‑l
PMID 24126493

Crosstalk between monocytes and renal mesangial cells via interaction of metalloproteinases and fractalkine in diabetic nephropathy.

Wang Y, Wei Q, Liu Q, Li Z, Zhou L, Zou F, Yuan Y, Sun Z.SourceDepartment of Endocrinology, Zhongda Hospital, Institute of Diabetes, Medical School, Southeast University, Nanjing, Jiangsu 210009, P.R. China.
Molecular medicine reports.Mol Med Rep.2013 Dec;8(6):1817-23. doi: 10.3892/mmr.2013.1703. Epub 2013 Sep 25.
An increasing number of studies suggest that the activation of innate immunity with the development of a chronic low‑grade inflammatory response is a factor in the pathogenesis of diabetic nephropathy (DN). Advanced glycation end products (AGEs), chemokines and matrix metalloproteinases (MMPs) are
PMID 24068281

Direct Infection of Primary Salivary Gland Epithelial Cells by Human T Lymphotropic Virus Type I in Patients With Sjögren's Syndrome

Nakamura Hideki,Takahashi Yoshiko,Yamamoto-Fukuda Tomomi,Horai Yoshiro,Nakashima Yoshikazu,Arima Kazuhiko,Nakamura Tatsufumi,Koji Takehiko,Kawakami Atsushi
Arthritis & Rheumatology 67(4), 1096-1106, 2015-04
… Results Among the SGECs, 7.8 ± 1.3% (mean ± SD) were positive for HTLV-I-related proteins after 96-hour coculture with HCT-5 cells. … The presence of HTLV-I proviral DNA in SGECs after coculture with HCT-5 cells was detected by in situ polymerase chain reaction. … After coculture of SGECs with HCT-5, the expression of cytokines and chemokines, including soluble intercellular adhesion molecule 1, RANTES, and interferon γ-induced protein 10 kd (IP-10/CXCL10) was increased in a time-dependent manner. …
NAID 120005603845

Application of a single-colony coculture technique to the isolation of hitherto unculturable gut bacteria

Expansion of mouse hematopoietic progenitor cells in three-dimensional cocultures on frozen-thawed stromal cell layers formed within porous scaffolds

Miyoshi Hirotoshi,Morita Misa,Ohshima Norio,Sato Chiaki
Experimental hematology 43(2), 115-124, 2015-02
… Because 3D frozen-thawed stromal cell lines are easy to handle, 3D coculture of HCs on frozen-thawed stromal cell lines may be an effective and convenient method for expanding primitive HCs. …
NAID 120005596201