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Backbone circularization of Bacillus subtilis family 11 xylanase increases its thermostability and its resistance against aggregation.

Waldhauer MC1, Schmitz SN1, Ahlmann-Eltze C1, Gleixner JG1, Schmelas CC1, Huhn AG1, Bunne C1, Büscher M1, Horn M1, Klughammer N1, Kreft J1, Schäfer E1, Bayer PA1, Krämer SG2, Neugebauer J2, Wehler P1, Mayer MP3, Eils R4, Di Ventura B1.
Molecular bioSystems.Mol Biosyst.2015 Dec;11(12):3231-43. doi: 10.1039/c5mb00341e.
The activity of proteins is dictated by their three-dimensional structure, the native state, and is influenced by their ability to remain in or return to the folded native state under physiological conditions. Backbone circularization is thought to increase protein stability by decreasing the confor
PMID 26434634

Combinatorial control of Drosophila circular RNA expression by intronic repeats, hnRNPs, and SR proteins.

Kramer MC1, Liang D1, Tatomer DC1, Gold B2, March ZM1, Cherry S2, Wilusz JE1.
Genes & development.Genes Dev.2015 Oct 15;29(20):2168-82. doi: 10.1101/gad.270421.115. Epub 2015 Oct 8.
Thousands of eukaryotic protein-coding genes are noncanonically spliced to produce circular RNAs. Bioinformatics has indicated that long introns generally flank exons that circularize in Drosophila, but the underlying mechanisms by which these circular RNAs are generated are largely unknown. Here, u
PMID 26450910

Tidal Heating of Earth-like Exoplanets around M Stars: Thermal, Magnetic, and Orbital Evolutions.

Driscoll PE1, Barnes R1.
Astrobiology.Astrobiology.2015 Sep;15(9):739-60. doi: 10.1089/ast.2015.1325.
The internal thermal and magnetic evolution of rocky exoplanets is critical to their habitability. We focus on the thermal-orbital evolution of Earth-mass planets around low-mass M stars whose radiative habitable zone overlaps with the "tidal zone," where tidal dissipation is expected to be a signif
PMID 26393398

Cellular Proteins Act as Bridge Between 5' and 3' Ends of the Coxsackievirus B3 Mediating Genome Circularization During RNA Translation.

Souii A1, M'hadheb-Gharbi MB, Gharbi J.
Current microbiology.Curr Microbiol.2015 Sep;71(3):387-95. doi: 10.1007/s00284-015-0866-y. Epub 2015 Jul 3.
The positive single-stranded RNA genome of the Coxsackievirus B3 (CVB3) contains a 5' untranslated region (UTR) which hosts the internal ribosome entry site (IRES) element that governs cap-independent translation initiation and a polyadenylated 3' UTR which is required for stimulating the IRES activ
PMID 26139182