WordNet

being long-lasting and recurrent or characterized by long suffering; "chronic indigestion"; "a chronic shortage of funds"; "a chronic invalid"
of long duration; "chronic money problems" (同)continuing
habitual; "a chronic smoker" (同)inveterate
any of several psychotic disorders characterized by distortions of reality and disturbances of thought and language and withdrawal from social contact (同)schizophrenic_disorder, schizophrenic psychosis, dementia_praecox

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Decreasing self-reported cognitive biases and increasing clinical insight through meta-cognitive training in patients with chronic schizophrenia.

Gawęda Ł1, Krężołek M2, Olbryś J3, Turska A3, Kokoszka A3.
Journal of behavior therapy and experimental psychiatry.J Behav Ther Exp Psychiatry.2015 Sep;48:98-104. doi: 10.1016/j.jbtep.2015.02.002. Epub 2015 Mar 5.
BACKGROUND AND OBJECTIVES: The aim of this study was to assess the impact of meta-cognitive training (MCT) on cognitive biases, symptoms, clinical insight, and general functioning among low-level functioning persons diagnosed with chronic schizophrenia who were attending a daily Community Social Sup
PMID 25775947

Circulating brain derived neurotrophic factor levels and its relation with exercise in chronic patients with schizophrenia.

Dogan T1, Agilli M2.
Psychiatry research.Psychiatry Res.2015 Aug 15;228(2):233. doi: 10.1016/j.psychres.2015.03.010.
PMID 26051419

Hippocampal volume and depressive symptoms are linked to serum IL-18 in schizophrenia.

Bossù P1, Piras F1, Palladino I1, Iorio M1, Salani F1, Ciaramella A1, Chiapponi C1, Caltagirone C1, Spalletta G1.
Neurology® neuroimmunology & neuroinflammation.Neurol Neuroimmunol Neuroinflamm.2015 May 7;2(4):e111. doi: 10.1212/NXI.0000000000000111. eCollection 2015.
OBJECTIVE: Since schizophrenia (SCZ) is often accompanied by hippocampal abnormalities and dysregulation of cytokine production, this study aimed to investigate the impact of the cytokine interleukin (IL)-18, whose biological system appears to be perturbed in SCZ, on brain structure and clinical sev
PMID 25977936

Experimental Evidence for the Involvement of PDLIM5 in Mood Disorders in Hetero Knockout Mice

Horiuchi Yasue,Ishikawa Maya,Kaito Nobuko,Iijima Yoshimi,Tanabe Yoshiko,Ishiguro Hiroki,Arinami Tadao,飯嶋良味,有波忠雄
PLoS ONE 8(4), e59320, 2013-04-00
… and chronic methamphetamine (METH) administration may model mania and the evolution of mania into psychotic mania or schizophrenia-like behavioral changes, respectively.MethodsTo address whether the downregulation of PDLIM5 protects against manic symptoms and cause susceptibility to depressive symptoms, we evaluated the effects of reduced Pdlim5 levels on acute and chronic METH-induced locomotor hyperactivity, prepulse inhibition, and forced swimming by using Pdlim5 hetero knockout (KO) …
NAID 120005285765

西尾綾子,角卓郎,山田雅人,桑波田悠子
Nippon Jibiinkoka Gakkai Kaiho 116(2), 97-102, 2013
東京都では精神科病院入院中の患者が身体疾患を発症した場合, 治療可能な病院へ転院させる医療事業 (東京都精神科患者身体合併症医療事業) を行っている. 青梅市立総合病院は同事業に参加し, 当科では2005年以降15例の耳鼻咽喉科疾患の治療を担当した. 背景の精神疾患は統合失調症12例, その他3例であった. 合併した耳鼻咽喉科疾患は頭頸部悪性腫瘍9例, その他6例であった. 精神科患者の身体疾患治 …
NAID 130003372899