cholesterol ester

コレステロールエステル

関

cholesteryl ester

同

CE

WordNet

1. of the period coinciding with the Christian era; preferred by some writers who are not Christians; "in 200 CE" (同)C.E., Common Era
2. an animal sterol that is normally synthesized by the liver; the most abundant steroid in animal tissues (同)cholesterin
3. formed by reaction between an acid and an alcohol with elimination of water

PrepTutorEJDIC

1. コレステロール(胆汁・血液・神経組織などの脂肪性成分)
2. エステル(酸とアルコールから水を分離してできる化合物の総称)

UpToDate Contents

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• 1. HDL代謝およびHDLコレステロール値異常の患者に対するアプローチ hdl metabolism and approach to the patient with abnormal hdl cholesterol levels
• 2. リポ蛋白の分類、代謝、およびアテローム性動脈硬化症における役割 lipoprotein classification metabolism and role in atherosclerosis
• 3. 適度なアルコール摂取の心血管に対する利益とリスク cardiovascular benefits and risks of moderate alcohol consumption
• 4. 食事または栄養補助食品による脂質低下 lipid lowering with diet or dietary supplements
• 5. 二次予防における脂質（高コレステロール血症を含む）の治療 treatment of lipids including hypercholesterolemia in secondary prevention

English Journal

• Phase diagram of a 4-component lipid mixture: DSPC/DOPC/POPC/chol.

• Konyakhina TM, Wu J, Mastroianni JD, Heberle FA, Feigenson GW.SourceDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA.
• Biochimica et biophysica acta.Biochim Biophys Acta.2013 Sep;1828(9):2204-14. doi: 10.1016/j.bbamem.2013.05.020. Epub 2013 Jun 7.
• We report the first 4-component phase diagram for the lipid bilayer mixture, DSPC/DOPC/POPC/chol (distearoylphosphatidylcholine/dioleoylphosphatidylcholine/1-palmitoyl, 2-oleoylphosphatidylcholine/cholesterol). This phase diagram, which has macroscopic Ld+Lo phase domains, clearly shows that all pha
• PMID 23747294

• Dose-dependent alterations in gene expression and testosterone production in fetal rat testis after exposure to di-n-hexyl phthalate.

• Saillenfait AM, Sabaté JP, Robert A, Rouiller-Fabre V, Roudot AC, Moison D, Denis F.SourceInstitut National de Recherche et de Sécurité, Vandoeuvre, France.
• Journal of applied toxicology : JAT.J Appl Toxicol.2013 Sep;33(9):1027-35. doi: 10.1002/jat.2896. Epub 2013 Jun 11.
• In utero exposure to the phthalate ester plasticizer di-n-hexyl phthalate (DnHP) is known to affect the development of the male reproductive system and induce alterations in androgen-dependent tissues of male rat offspring. Male reproductive malformations produced by several phthalates have been cau
• PMID 23754470

• Effects of a high-fat, high-cholesterol diet on brain lipid profiles in apolipoprotein E ε3 and ε4 knock-in mice.

• Lim WL, Lam SM, Shui G, Mondal A, Ong D, Duan X, Creegan R, Martins IJ, Sharman MJ, Taddei K, Verdile G, Wenk MR, Martins RN.SourceSchool of Psychiatry and Clinical Neurosciences, The University of Western Australia, Nedlands, Australia.
• Neurobiology of aging.Neurobiol Aging.2013 Sep;34(9):2217-24. doi: 10.1016/j.neurobiolaging.2013.03.012. Epub 2013 Apr 18.
• Apolipoprotein E (ApoE) is important in facilitating the transport of lipids (cholesterol, phospholipids, and sulfatides) and plays a fundamental role in normal lipid metabolism. High cholesterol levels increases the risk of developing Alzheimer's disease. In this study, we investigated the effects
• PMID 23601809

Japanese Journal

• コレステロール逆転送におけるCETPの意義とCETP阻害薬の是非 (AYUMI HDLの多面的作用とその異常 : 善玉HDLと悪玉HDL)

• 増田 大作
• 医学のあゆみ 245(6), 517-524, 2013-05-11
• NAID 40019642269

• Therapeutic Approaches to the Regulation of Metabolism of High-Density Lipoprotein:– Novel HDL-Directed Pharmacological Intervention and Exercise –

• Zhang Bo,Kawachi Emi,Miura Shin-ichiro,Uehara Yoshinari,Matsunaga Akira,Kuroki Masahide,Saku Keijiro
• Circulation Journal 77(11), 2651-2663, 2013
• … High-density lipoprotein (HDL) and low-density lipoprotein (LDL) particles transport cholesterol in plasma and play an important role in cellular cholesterol homeostasis, which influences cell function. … The risk of coronary artery disease (CAD) associated with high levels of LDL-cholesterol (LDL-C) can be reduced by treatment with statins, which reduce LDL-C levels by inhibiting cellular cholesterol synthesis. …
• NAID 130003382136

• The Mechanism of Action of Bufalin in Inhibition of Lipid Droplet Accumulation in Mouse Macrophages

• Kobayashi Keisuke,Ohshiro Taichi,Matsuda Daisuke,Jiang Wei,Hong Bin,Si Shuyi,Tomoda Hiroshi
• Biological and Pharmaceutical Bulletin 36(3), 364-369, 2013
• … Bufalin selectively inhibited synthesis of [14C]cholesteryl ester (CE), a main component of lipid droplet, from [14C]oleic acid and [14C]cholesterol with IC50 values of 8.6 µM and 10 µM, respectively. … The postlysosomal metabolism of cholesterol to CE in macrophages was also inhibited by the compound with a similar IC50 value of 13.2 µM. …
• NAID 130003382077

Related Links

• Cholesteryl ester - Wikipedia, the free encyclopedia

A cholesteryl ester is, as its name would imply, an ester of cholesterol. The ester bond is formed between the carboxylate group of a fatty acid and the hydroxyl group of cholesterol. Cholesteryl esters have a lower solubility in water than ...

• Sterols 1. Cholesterol and cholesterol esters, struncture, occurrence ...

21 Jan 2013 ... Sterols 1. Cholesterol and cholesterol esters, struncture, occurrence, biochemistry and analysis.

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★リンクテーブル★

リンク元	「CE」「cholesteryl ester」「コレステロールエステル」
拡張検索	「cholesterol ester storage disease」「cholesterol ester hydrolase」「cholesterol ester crystal」「cholesterol esterase」
関連記事	「cholesterol」

「CE」

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• コレステロールエステル cholesterol ester
• キャピラリー電気泳動 capillary electrophoresis

　

「cholesteryl ester」

　　[★]

コレステリルエステル、コレステロールエステル

関

cholesterol ester

「コレステロールエステル」

　　[★]

英

cholesterol ester CE

関

コレステロール

「cholesterol ester storage disease」

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コレステロールエステル蓄積症

関

cholesteryl ester storage disease

同

CESD

「cholesterol ester hydrolase」

　　[★] コレステロールエステルヒドロラーゼ

「cholesterol ester crystal」

　　[★] コレステロールエステル結晶

「cholesterol esterase」

　　[★] コレステロールエステラーゼ

「cholesterol」

　　[★] コレステロール