- 同
- ACAT
WordNet
- an animal sterol that is normally synthesized by the liver; the most abundant steroid in animal tissues (同)cholesterin
PrepTutorEJDIC
- コレステロール(胆汁・血液・神経組織などの脂肪性成分)
UpToDate Contents
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- 1. HDL代謝およびHDLコレステロール値異常の患者に対するアプローチ hdl metabolism and approach to the patient with abnormal hdl cholesterol levels
- 2. リポ蛋白の分類、代謝、およびアテローム性動脈硬化症における役割 lipoprotein classification metabolism and role in atherosclerosis
- 3. 二次予防における脂質（高コレステロール血症を含む）の治療 treatment of lipids including hypercholesterolemia in secondary prevention
- 4. リポ蛋白および止血因子に対する運動の影響 effects of exercise on lipoproteins and hemostatic factors
- 5. 棘状細胞（棘状赤血球および有棘赤血球）と標的細胞 spiculated cells echinocytes and acanthocytes and target cells
English Journal
- Effects of a high-fat, high-cholesterol diet on brain lipid profiles in apolipoprotein E ɛ3 and ɛ4 knock-in mice.
- Lim WL, Lam SM, Shui G, Mondal A, Ong D, Duan X, Creegan R, Martins IJ, Sharman MJ, Taddei K, Verdile G, Wenk MR, Martins RN.SourceSchool of Psychiatry and Clinical Neurosciences, The University of Western Australia, Nedlands, Australia; School of Medical Sciences, Edith Cowan University, Joondalup, Australia.
- Neurobiology of aging.Neurobiol Aging.2013 Sep;34(9):2217-24. doi: 10.1016/j.neurobiolaging.2013.03.012. Epub 2013 Apr 18.
- Apolipoprotein E (ApoE) is important in facilitating the transport of lipids (cholesterol, phospholipids, and sulfatides) and plays a fundamental role in normal lipid metabolism. High cholesterol levels increases the risk of developing Alzheimer's disease. In this study, we investigated the effects
- PMID 23601809
- HPLC-FLD determination of NBD-cholesterol, its ester and other metabolites in cellular lipid extracts.
- Cao XZ, Mi TY, Li L, Vermeer MA, Zhang CC, Huang N, Manoj JK.SourceUnilever R&D Shanghai, 66 Lin Xin Road, Shanghai, 200335, People's Republic of China.
- Biomedical chromatography : BMC.Biomed Chromatogr.2013 Jul;27(7):910-5. doi: 10.1002/bmc.2881. Epub 2013 Mar 25.
- 22-[N(-7-Nitrobenz-2-oxa-1,3-diazol-4-yl)amino]-23,24-bisnor-5-cholen-3β-ol (NBD-cholesterol), a fluorescent cholesterol analog, was an extragenous cholesterol tracer used to study cholesterol absorption and metabolism in cultured cells. In order to measure free intracellular cholesterol and its es
- PMID 23526237
- Synthesis and structure-activity relationship of pyripyropene A derivatives as potent and selective acyl-CoA:cholesterol acyltransferase 2 (ACAT2) inhibitors: Part 3.
- Ohtawa M, Yamazaki H, Ohte S, Matsuda D, Ohshiro T, Rudel LL, Omura S, Tomoda H, Nagamitsu T.SourceGraduate School of Pharmaceutical Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan.
- Bioorganic & medicinal chemistry letters.Bioorg Med Chem Lett.2013 Jul 1;23(13):3798-801. doi: 10.1016/j.bmcl.2013.04.075. Epub 2013 May 8.
- In an effort to develop potent and selective inhibitors toward ACAT2, structure-activity relationship studies were carried out using derivatives based on pyripyropene A (PPPA, 1). In particular, we investigated the possibility of introducing appropriate 1,11-O-benzylidene and 7-O-substituted benzoyl
- PMID 23711919
Japanese Journal
- アミド軸不斉の化学 : 生物活性発現に寄与する立体構造の解明研究
- 田畑 英嗣
- 薬学雑誌 133(8), 853-866, 2013
- NAID 40019778248
- The Mechanism of Action of Bufalin in Inhibition of Lipid Droplet Accumulation in Mouse Macrophages
- Kobayashi Keisuke,Ohshiro Taichi,Matsuda Daisuke,Jiang Wei,Hong Bin,Si Shuyi,Tomoda Hiroshi
- Biological and Pharmaceutical Bulletin 36(3), 364-369, 2013
- … Bufalin selectively inhibited synthesis of [14C]cholesteryl ester (CE), a main component of lipid droplet, from [14C]oleic acid and [14C]cholesterol with IC50 values of 8.6 µM and 10 µM, respectively. … The postlysosomal metabolism of cholesterol to CE in macrophages was also inhibited by the compound with a similar IC50 value of 13.2 µM. …
- NAID 130003382077
- アミド軸不斉の化学—生物活性発現に寄与する立体構造の解明研究—
- 田畑 英嗣
- YAKUGAKU ZASSHI 133(8), 857-866, 2013
- … Anilide derivatives with the seven-membered-ring benzolactams (derivatives of I: 6-8) and the N-benzoyl derivatives of 1,5-benzodiazepines (derivatives of II: 11-ii-14-ii) were successfully synthesized as new, highly potent acyl-CoA:cholesterol acyltransferase inhibitors and the vaptan class of vasopressin receptor ligands, respectively. …
- NAID 130003361980
Related Links
- [ Lecithin-cholesterol_acyltransferase]の項目はありません。 情報提供元のWikipediaにはこの項目があるかもしれません。 もし項目がない場合はWikipediaに参加してこの項目を追加しませんか？ [Lecithin-cholesterol_acyltransferase] の ...
- In 1935, Sperry was the first to recognize that when human plasma was incubated at 37 C, a marked esterification of free cholesterol occurred (1). He attributed this to enzymatic activity, as the effect was abolished when the plasma ...
Related Pictures
★リンクテーブル★
| リンク元 | 「コレステロールアシルトランスフェラーゼ」「sterol O-acyltransferase」「コレステロールアシル転移酵素」「コレステロールアシル基転移酵素」 |
| 拡張検索 | 「acyl-CoA-cholesterol acyltransferase」 |
| 関連記事 | 「acyltransferase」「cholesterol」 |
「コレステロールアシルトランスフェラーゼ」
- 英
- cholesterol acyltransferase
- 関
- アシルCoA・コレステロールアシルトランスフェラーゼ、ステロールO-アシルトランスフェラーゼ、コレステロールアシル転移酵素、コレステロールアシル基転移酵素
「sterol O-acyltransferase」
ステロールO-アシルトランスフェラーゼ、ステロールO-アシル基転移酵素、ステロールO-アシル転移酵素
「コレステロールアシル転移酵素」
「コレステロールアシル基転移酵素」
「acyl-CoA-cholesterol acyltransferase」
アシルCoA・コレステロールアシルトランスフェラーゼ、アシルCoA・コレステロールアシル基転移酵素