Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/06/22 22:01:03」(JST)

wiki en

A cholescintigraphy scan, also known as: hepatobiliary iminodiacetic acid (HIDA), paraisopropyl iminodiacetic acid (PIPIDA), or diisopropyl iminodiacetic acid (DISIDA) scan is a nuclear imaging procedure to evaluate the health and function of the gallbladder. A radioactive tracer is injected through any accessible vein, then allowed to circulate to the liver, where it is excreted into the biliary system and stored by the gallbladder and biliary system.^[1]

In the absence of disease, the gallbladder is visualized within 1 hour of the injection of the radioactive tracer. If the gallbladder is not visualized within 4 hours after the injection, this indicates either cholecystitis or cystic duct obstruction. This investigation is usually conducted after an ultrasound examination of the abdominal right upper quadrant for an individual presenting with pain. If the non-invasive ultrasound examination fails to demonstrate gall stones (or other obstruction to the gall bladder or biliary tree) in an attempt to establish a cause of right upper quadrant pain, this cholescintigraphy scan can be performed as a more sensitive and specific test. Cholescintigraphy scans are not generally done first line due to their increased cost and invasiveness.

Cholescintigraphy for acute cholecystitis has sensitivity of 97%, specificity of 94%.^[2] Several investigators have found the sensitivity being consistently higher than 90% though specificity has varied from 73%- 99%, yet compared to ultrasonography, cholescintigraphy has proven to be superior.^[3] The scan is also important to differentiate between neonatal hepatitis and biliary atresia, because an early surgical intervention in form of Kasai portoenterostomy or hepatoportoenterostomy can save the life of the baby as the chance of a successful operation after 3 months seriously decreases.^[4]

99m
Tc hydroxy-iminodiacetic acid (HIDA/Lidofenin) is rarely used currently, as 99m
Tc paraisopropyl iminodiacetic acid (PIPIDA), 99m
Tc diisopropylacetanilido iminodiacetic acid (DISIDA/Disofenin) or 99m
Tc bromo-2,4,6-trimethylacetanilido iminodiaceticacid (BrIDA/Mebrofenin) have replaced it,^[5]^[6] but the term HIDA remains.

References

^ Michael, Picco, M.D. "HIDA scan (cholescintigraphy): Why is it performed?". Mayo Clinic. Retrieved 2007-12-11.
^ Shea JA, Berlin JA, Escarce JJ, Clarke JR, Kinosian BP, Cabana MD, et al. (1994). "Revised estimates of diagnostic test sensitivity and specificity in suspected biliary tract disease.". Arch Intern Med 154 (22): 2573–81. doi:10.1001/archinte.154.22.2573. PMID 7979854.
^ L. Santiago Medina; C. Craig Blackmore; Kimberly Applegate (29 April 2011). Evidence-Based Imaging: Improving the Quality of Imaging in Patient Care. Springer. p. 530. ISBN 978-1-4419-7776-2. Retrieved 23 August 2012.
^ Jorge A. Soto; Brian C. Lucey (27 April 2009). Emergency Radiology: The Requisites. Elsevier Health Sciences. p. 380. ISBN 978-0-323-05407-2. Retrieved 23 August 2012.
^ Krishnamurthy, Gerbail T.; Krishnamurthy, Shakuntala (31 July 2009). Nuclear Hepatology: A Textbook of Hepatobiliary Diseases. Springer. ISBN 978-3-642-00647-0.
^ Puthenedam, Manjula. "SNM issues guidelines for hepatobiliary scintigraphy". Retrieved 2012-12-02.

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 急性胆嚢炎の病因、臨床的特徴および診断 pathogenesis clinical features and diagnosis of acute cholecystitis
2. 成人における胆嚢機能障害 functional gallbladder disorder in adults
3. オッディ括約筋機能不全の臨床症状よび診断 clinical manifestations and diagnosis of sphincter of oddi dysfunction
4. 成人における合併症のない胆石症 uncomplicated gallstone disease in adults
5. 無石胆嚢炎 acalculous cholecystitis

English Journal

Hepatobiliary Scintigraphy in 2014.

Ziessman HA.
Journal of nuclear medicine technology.J Nucl Med Technol.2014 Dec;42(4):249-259.
Cholescintigraphy with 99mTc-hepatobiliary radiopharmaceuticals has been an important, clinically useful diagnostic imaging study for almost 4 decades. It continues to be in much clinical demand; however, the indications, methodology, and interpretative criteria have evolved over the years. This rev
PMID 25472513

Fatty meal ultrasonography in chronic acalculous cholecystitis.

Donen A1, Kantor R2.
Journal of surgical case reports.J Surg Case Rep.2014 Nov 18;2014(11). pii: rju120. doi: 10.1093/jscr/rju120.
Chronic acalculous cholecystits typically presents with biliary symptoms, normal blood tests and unremarkable ultrasound, computerized tomography and magnetic resonance cholangiopancreatography. However, cholescintigraphy may show reduced gallbladder ejection fraction (GBEF). There are no reports on
PMID 25409675

Pain Provocation and Low Gallbladder Ejection Fraction with CCK Cholescintigraphy Are Not Predictive of Chronic Acalculous Gallbladder Disease Symptom Relief After Cholecystectomy.

Edwards MA1, Mullenbach B, Chamberlain SM.
Digestive diseases and sciences.Dig Dis Sci.2014 Nov;59(11):2773-8. doi: 10.1007/s10620-014-3213-4. Epub 2014 May 23.
INTRODUCTION: Chronic acalculous gallbladder disease (CAGD) falls within the spectrum of diseases associated with gallbladder dysmotility. Cholecystokinin-cholescintigraphy (CCK-CS) has been used to evaluate for CAGD, with a gallbladder ejection fraction (GBEF) of <35 % being indicative of gallb
PMID 24852884

Japanese Journal

Gallbladder ejection fraction measured by fatty meal cholescintigraphy : is it affected by extended gallbladder emptying data acquisition time?

AL-MUQBEL Kusai M.
Annals of nuclear medicine 24(1), 29-34, 2010-01-01
NAID 10026099874

Usefulness of fatty meal-stimulated cholescintigraphy in the diagnosis and treatment of chronic acalculous cholecystitis

AL-MUQBEL Kusai,BANI HANI Mohammed,DARADKEH Mohammad,RASHDAN Abdullah
Annals of nuclear medicine 23(2), 137-142, 2009-02-01
NAID 10025135631

Congenital Bronchobiliary Fistula in a 65-year-old Woman

Uramoto Hideshi,Kawano Osamu,Sugimoto Mineharu,Yamagata Haruhiko,Kohrogi Hirotsugu
Internal Medicine 47(14), 1367-1370, 2008
… Cholescintigraphy showed dilatation of the left bile duct and radiotracer pooling at the top edge of the left hepatic lobe. …
NAID 130000078822

Related Pictures

★リンクテーブル★

リンク元	「肝胆道シンチグラム」

「肝胆道シンチグラム」

Cholescintigraphy
	Intervention
	Normal hepatobiliary scan (HIDA scan). The nuclear medicine hepatobiliary scan is clinically useful in the detection of the gallbladder disease.
ICD-9-CM	92.02
OPS-301 code	3-707.6
	[edit on Wikidata]

　　[★]

英: hepatobiliary scintigram
同: (方法)肝胆道シンチグラフィ hepatobiliary scintigraphy、胆道シンチグラフィ cholescintigraphy biliary scintigraphy, 肝胆道スキャン hepatobiliary scan

N-ピリドキシル-5-メチルトリプトファンテクネチウム(99mTc) 99mTc-PMTを用いるシンチグラフィー
肝細胞から排泄され、胆管・胆道を経て腸管に排泄される。胆汁の排泄障害などを目的として実施される。

[1] Michael, Picco, M.D. "HIDA scan (cholescintigraphy): Why is it performed?". Mayo Clinic. Retrieved 2007-12-11.

[pmid7979854-2] Shea JA, Berlin JA, Escarce JJ, Clarke JR, Kinosian BP, Cabana MD, et al. (1994). "Revised estimates of diagnostic test sensitivity and specificity in suspected biliary tract disease.". Arch Intern Med 154 (22): 2573–81. doi:10.1001/archinte.154.22.2573. PMID 7979854.

[MedinaBlackmore2011-3] L. Santiago Medina; C. Craig Blackmore; Kimberly Applegate (29 April 2011). Evidence-Based Imaging: Improving the Quality of Imaging in Patient Care. Springer. p. 530. ISBN 978-1-4419-7776-2. Retrieved 23 August 2012.

[SotoLucey2009-4] Jorge A. Soto; Brian C. Lucey (27 April 2009). Emergency Radiology: The Requisites. Elsevier Health Sciences. p. 380. ISBN 978-0-323-05407-2. Retrieved 23 August 2012.

[5] Krishnamurthy, Gerbail T.; Krishnamurthy, Shakuntala (31 July 2009). Nuclear Hepatology: A Textbook of Hepatobiliary Diseases. Springer. ISBN 978-3-642-00647-0.

[6] Puthenedam, Manjula. "SNM issues guidelines for hepatobiliary scintigraphy". Retrieved 2012-12-02.

匿名

検索

案内

案内

cholescintigraphy