WordNet

the physiological state produced by a poison or other toxic substance (同)toxic condition, intoxication
the act of giving poison to a person or animal with the intent to kill

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[No authors listed]
Journal of gerontological nursing.J Gerontol Nurs.2014 Jun;40(6):5-6. doi: 10.3928/00989134-20140430-89.
PMID 24877503

Clioquinol induces DNA double-strand breaks, activation of ATM, and subsequent activation of p53 signaling.

Katsuyama M1, Iwata K, Ibi M, Matsuno K, Matsumoto M, Yabe-Nishimura C.
Toxicology.Toxicology.2012 Sep 4;299(1):55-9. doi: 10.1016/j.tox.2012.05.013. Epub 2012 May 22.
Clioquinol, a Cu²⁺/Zn²⁺/Fe²⁺ chelator/ionophor, was used extensively in the mid 1900s as an amebicide for treating indigestion and diarrhea. It was eventually withdrawn from the market because of a link to subacute myelo-optic neuropathy (SMON) in Japan. The pathogenesis of SMON, however, i
PMID 22627294

Kimura E1, Hirano T, Yamashita S, Hirai T, Uchida Y, Maeda Y, Uchino M.
Spinal cord.Spinal Cord.2011 Feb;49(2):182-5. doi: 10.1038/sc.2010.68. Epub 2010 Jun 15.
STUDY DESIGN: Case study.OBJECTIVES: Subacute myelo-optico-neuropathy (SMON) is a severe neuro-degenerative disorder caused by poisoning due to over-dose and prolonged oral administration of clioquinol; this disorder was more frequent during 1957-1970. It is characterized by axonal degeneration and
PMID 20548321

Research Concerning the Effects of Electrical Acupuncture Therapy on Post SMON Disease Symptoms

太田恵三,花籠良一
日本鍼灸治療学会誌 25(3), 30-42,69, 1976
… Presently in Japan there are approximately 10, 000 patients suffering from the aftereffects of SMON (Subacute Myelo-Optico-Neuropathy), a disease which has occured in large proportions in recent years as a result of chinoform poisoning.Main symptoms include bilateral paresis, paresthesia of the lower extremities and gastric symptoms. …
NAID 130004386486