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1. 化学療法誘発性悪心および嘔吐の予防および治療 prevention and treatment of chemotherapy induced nausea and vomiting
2. 成人における抗癌剤の投与 dosing of anticancer agents in adults
3. 高齢者における癌に対する全身化学療法 systemic chemotherapy for cancer in elderly persons
4. プラチナベースの化学療法の神経学的合併症の概要 overview of neurologic complications of platinum based chemotherapy
5. 非プラチナ製剤ベースの癌化学療法の神経学的合併症の概要 overview of neurologic complications of non platinum cancer chemotherapy

Impairment of stress granule assembly via inhibition of the eIF2alpha phosphorylation sensitizes glioma cells to chemotherapeutic agents.

Vilas-Boas Fde A1, da Silva AM2, de Sousa LP3, Lima KM3, Vago JP3, Bittencourt LF1, Dantas AE4, Gomes DA4, Vilela MC5, Teixeira MM4, Barcelos LS6,7.
Journal of neuro-oncology.J Neurooncol.2016 Apr;127(2):253-60. doi: 10.1007/s11060-015-2043-3. Epub 2016 Jan 5.
Malignant gliomas are a lethal type of brain tumors that poorly respond to chemotherapeutic drugs. Several therapy resistance mechanisms have been characterized. However, the response to stress through mRNA translational control has not been evaluated for this type of tumor. A potential target would
PMID 26732083

Wong DY1, Ong WW1, Ang WH2,3.
Angewandte Chemie (International ed. in English).Angew Chem Int Ed Engl.2015 May 26;54(22):6483-7. doi: 10.1002/anie.201500934. Epub 2015 Apr 14.
There is compelling evidence suggesting that the immune-modulating effects of many conventional chemotherapeutics, including platinum-based agents, play a crucial role in achieving clinical response. One way in which chemotherapeutics can engage a tumor-specific immune response is by triggering an i
PMID 25873535

Tyrosyl-DNA phosphodiesterase I resolves both naturally and chemically induced DNA adducts and its potential as a therapeutic target.

Comeaux EQ1, van Waardenburg RC.
Drug metabolism reviews.Drug Metab Rev.2014 Nov;46(4):494-507. doi: 10.3109/03602532.2014.971957. Epub 2014 Oct 20.
DNA is subject to a wide range of insults, resulting from endogenous and exogenous sources that need to be metabolized/resolved to maintain genome integrity. Tyrosyl-DNA phosphodiesterase I (Tdp1) is a eukaryotic DNA repair enzyme that catalyzes the removal of covalent 3'-DNA adducts. As a phospholi
PMID 25327705

M-protein kinetics in multiple myeloma treated with melphalan, ifosfamide, prednisolone, nitrosourea and vincristine in combination.

Ishii Hirofumi
Acta Medica Okayama 42(5), 1988-10
… <p>Patients with multiple myeloma were treated chemotherapeutically with a combination of melphalan, ifosfamide, prednisolone, nitrosourea and vincristine (MIP-NV therapy). …
NAID 120002312406

早川芳宏
有機合成化学協会誌 46(8), 753-766, 1988
… On the other hand, immunochemical studies on 2-5 A implied that the analogs having adenylyl (2'-5') adenosine structure are chemotherapeutically attractive compounds which are expected to show new biological activities. …
NAID 130000931286

Plasma prostaglandin levels in patients with gynecologic malignancies and its fluctuations during chemotherapeutically-induced gastrointestinal toxicity