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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/08/02 19:29:27」(JST)
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Cetyl alcohol[1]
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|
| Names |
| IUPAC name
Hexadecan-1-ol
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| Other names
Cetanol, Cetyl alcohol, Ethal, Ethol, Hexadecanol, Hexadecyl alcohol, Palmityl alcohol
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| Identifiers |
|
CAS Number
|
36653-82-4 Y |
| ChEBI |
CHEBI:16125 Y |
| ChEMBL |
ChEMBL706 Y |
| ChemSpider |
2581 Y |
| EC Number |
253-149-0 |
| Jmol 3D model |
Interactive image |
| KEGG |
D00099 Y |
| PubChem |
2682 |
| UNII |
936JST6JCN Y |
InChI
-
InChI=1S/C16H34O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17/h17H,2-16H2,1H3 Y
Key: BXWNKGSJHAJOGX-UHFFFAOYSA-N Y
-
InChI=1/C16H34O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17/h17H,2-16H2,1H3
Key: BXWNKGSJHAJOGX-UHFFFAOYAS
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|
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| Properties |
|
Chemical formula
|
C16H34O |
| Molar mass |
242.45 g·mol−1 |
| Appearance |
White crystals or flakes |
| Odor |
very faint |
| Density |
0.811 g/cm3 |
| Melting point |
49.3 °C (120.7 °F; 322.4 K) |
| Boiling point |
344 °C (651 °F; 617 K) |
|
Solubility in water
|
insoluble |
| Solubility |
very soluble in ether, benzene, chloroform
soluble in acetone
slightly soluble in alcohol |
| Acidity (pKa) |
16.20 |
|
Refractive index (nD)
|
1.4283 (79 °C) |
| Viscosity |
53 cP (75 °C) |
| Hazards |
| NFPA 704 |
|
| Flash point |
185 °C (365 °F; 458 K) |
| Lethal dose or concentration (LD, LC): |
|
LD50 (median dose)
|
5000 mg/kg (rat, oral) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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| Y verify (what is YN ?) |
| Infobox references |
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|
Cetyl alcohol , also known as hexadecan-1-ol and palmityl alcohol, is a fatty alcohol with the formula CH3(CH2)15OH. At room temperature, cetyl alcohol takes the form of a waxy white solid or flakes. The name cetyl derives from the whale oil (Latin: cetus) from which it was first isolated.[2]
Contents
- 1 Preparation
- 2 Uses
- 3 Side effects
- 4 Related compounds
- 5 References
Preparation
Cetyl alcohol was discovered in 1817 by the French chemist Michel Chevreul when he heated spermaceti, a waxy substance obtained from sperm whale oil, with caustic potash (potassium hydroxide). Flakes of cetyl alcohol were left behind on cooling.[3] Modern production is based around the reduction of palmitic acid, which is obtained from palm oil.
Uses
Cetyl alcohol is used in the cosmetic industry as an opacifier in shampoos, or as an emollient, emulsifier or thickening agent in the manufacture of skin creams and lotions.[4] It is also employed as a lubricant for nuts and bolts, and is the active ingredient in some "liquid pool covers" (forming a surface layer to reduce evaporation and retain heat).
Side effects
People who suffer from eczema can be sensitive to cetyl alcohol,[5][6] though this may be due to impurities rather than cetyl alcohol itself.[7] Ironically, this ingredient is sometimes included in medications for the treatment of eczema.[8]
Related compounds
References
- ^ Merck Index, 11th Edition, 2020.
- ^ Nordegren, Thomas (2002). The A-Z Encyclopedia of Alcohol and Drug Abuse. Universal Publishers. p. 165. ISBN 1-58112-404-X.
- ^ Booth, James Curtis (1862). The Encyclopedia of Chemistry, Practical and Theoretical. p. 429.
- ^ Smolinske, Susan C (1992). Handbook of Food, Drug, and Cosmetic Excipients. CRC Press. pp. 75–76. ISBN 0-8493-3585-X.
- ^ Gaul, LE (1969). "Dermatitis from cetyl and stearyl alcohols". Archives of dermatology 99 (5): 593. doi:10.1001/archderm.1969.01610230085016. PMID 4238421.
- ^ Soga, F; Katoh, N; Kishimoto, S (2004). "Contact dermatitis due to lanoconazole, cetyl alcohol and diethyl sebacate in lanoconazole cream". Contact dermatitis 50 (1): 49–50. doi:10.1111/j.0105-1873.2004.00271j.x. PMID 15059111.
- ^ Komamura, H; Doi, T; Inui, S; Yoshikawa, K (1997). "A case of contact dermatitis due to impurities of cetyl alcohol". Contact dermatitis 36 (1): 44–6. doi:10.1111/j.1600-0536.1997.tb00921.x. PMID 9034687.
- ^ Kato N; Numata T; Kanzaki T (1987). "Contact dermatitis due to Japanese pharmacopeia cetyl alcohol". Skin Research 29 (suppl 3): 258–262.
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Alcohols
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|
Straight-chain
primary
alcohols (1°) |
- Methanol (C
1)
- Ethanol (C
2)
- 1-Propanol (C
3)
- n-Butanol (C
4)
- 1-Pentanol (C
5)
- 1-Hexanol (C
6)
- 1-Heptanol (C
7)
- 1-Octanol (C
8)
- 1-Nonanol (C
9)
- 1-Decanol (C
10)
- Undecanol (C
11)
- Dodecanol (C
12)
- Tridecan-1-ol (C
13)
- 1-Tetradecanol (C
14)
- Pentadecan-1-ol (C
15)
- Cetyl alcohol (C
16)
- Heptadecan-1-ol (C
17)
- Stearyl alcohol (C
18)
- Nonadecan-1-ol (C
19)
- Arachidyl alcohol (C
20)
- Heneicosan-1-ol (C
21)
- Docosanol (C
22)
- Tricosan-1-ol (C
23)
- 1-Tetracosanol (C
24)
- Pentacosan-1-ol (C
25)
- 1-Hexacosanol (C
26)
- 1-Heptacosanol (C
27)
- 1-Octacosanol (C
28)
- 1-Nonacosanol (C
29)
- Triacontanol (C
30)
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|
Other primary
alcohols |
- Isobutanol (C
4)
- Isoamyl alcohol (C
5)
- 2-Methyl-1-butanol (C
5)
- Phenethyl alcohol (C
8)
- Tryptophol (C
10)
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|
Secondary
alcohols (2°) |
- Isopropanol (C
3)
- 2-Butanol (C
4)
- 2-Pentanol (C
5)
- 2-Hexanol (C
6)
- 2-Heptanol (C
7)
- Cyclohexanol (C
6)
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|
Tertiary
alcohols (3°) |
- tert-Butyl alcohol (C
4)
- tert-Amyl alcohol (C
5)
- 2-Methyl-2-pentanol (C
6)
- 2-Methylhexan-2-ol (C
7)
- 2-Methylheptan-2-ol (C
8)
- 3-Methyl-3-pentanol (C
6)
- 3-Methyloctan-3-ol (C
9)
|
English Journal
- One-pot preparation of a novel monolith for high performance liquid chromatography applications.
- Jiao X1, Shen S2, Shi T3.
- Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.J Chromatogr B Analyt Technol Biomed Life Sci.2015 Dec 15;1007:100-9. doi: 10.1016/j.jchromb.2015.10.028. Epub 2015 Nov 11.
- Various novel porous organic-based monoliths with the mode of hydrophobicity were synthesized by in situ free-radical crosslinking copolymerization and optimized for the separations of small molecules and high-performance reversed-phase chromatography (RP-chromatography). These monoliths contained c
- PMID 26590881
- Spray congealing as a microencapsulation technique to develop modified-release ibuprofen solid lipid microparticles: the effect of matrix type, polymeric additives and drug-matrix miscibility.
- Wong PC1, Heng PW1, Chan LW1.
- Journal of microencapsulation.J Microencapsul.2015 Dec;32(8):725-36. doi: 10.3109/02652048.2015.1073387. Epub 2015 Aug 4.
- This study aimed to achieve modified-release of ibuprofen (IBU) by encapsulation within lipid-based matrix materials [cetyl alcohol (CA), stearic acid (SA) and glyceryl dibehenate (GB)] using spray congealing to produce solid lipid microparticles (SLMs). Polymeric additives, polyvinyl-2-pyrrolidone-
- PMID 26242841
- Production of mono- and di-carboxylated polyethylene glycols as a factor obstacle to the successful ozonation-assisted biodegradation of ethoxylated compounds.
- Nakai S1, Okuda T2, Nishijima W3, Okada M4.
- Chemosphere.Chemosphere.2015 Oct;136:153-9. doi: 10.1016/j.chemosphere.2015.04.069. Epub 2015 May 15.
- Ozonation is believed to improve the biodegradability of organic compounds. In the present study, degradation of nonylphenol ethoxylates (NPEOs) was monitored in hybrid treatment systems consisting of ozonation and microbial degradation processes. We found that ozonation of NPEOs decreased, rather t
- PMID 25985303
Japanese Journal
- 症例報告 セタノール含有の複数の外用剤で接触皮膚炎をきたした1例
- 症例 ジフルプレドナート含有クリーム中のセタノールとクロタミトンによる接触皮膚炎の1例
- 症例報告 基剤成分セタノールによる接触皮膚炎の1例
Related Links
- The latest Tweets from せんえい (@cetanol). UTAUやがくっぽいどで活動！健音テイのホクロ。UTAUライブラリ｢声葉｣の1文字目であり2文字目の唯一の樹。｢C.ハーマネック｣の整備してる！アイコンはシジミさんから ﾆｺﾆｺ：http://t.co ...
- Information about Cetanol in the Columbia Encyclopedia, Computer Desktop Encyclopedia, computing dictionary. Cetanol definition of Cetanol in the Free Online Encyclopedia http://encyclopedia2.thefreedictionary.com/Cetanol ...
Related Pictures
★リンクテーブル★
[★]
- 英
- cetanol
- 関
- パルミチルアルコール
- パーム油などの植物油を精製して製造されている。
- パルミチン酸のカルボキシ基を還元して水酸基にしたもの。
- 示性式：CH3(CH2)15OH
- 化粧品や軟膏基剤として用いられいている。