cerebrospinal fluid rhinorrhea

髄液鼻漏

WordNet

1. subject to change; variable; "a fluid situation fraught with uncertainty"; "everything was unstable following the coup" (同)unstable
2. a substance that is fluid at room temperature and pressure
3. continuous amorphous matter that tends to flow and to conform to the outline of its container: a liquid or a gas
4. in cash or easily convertible to cash; "liquid (or fluid) assets" (同)liquid
5. affording change (especially in social status); "Britain is not a truly fluid society"; "upwardly mobile" (同)mobile
6. characteristic of a fluid; capable of flowing and easily changing shape (同)runny
7. of or relating to the brain and spinal cord; "cerebrospinal fluid"
8. persistent watery mucus discharge from the nose (as in the common cold)

PrepTutorEJDIC

1. 『流体』,流動体 / 『流動性の』,流動する / 流体の,流動体から成る / 変わりやすい,固定していない,浮動する
2. インフルエンザ,流感

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/01/21 17:28:41」(JST)

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Cerebrospinal fluid rhinorrhoea
Classification and external resources
ICD-10	G96.0
ICD-9	349.81
eMedicine	article/861126

CSF rhinorrhoea refers to the drainage of cerebrospinal fluid through the nose. Measures of CSF components such as glucose have been used in the past, but are neither sensitive nor specific; beta-2 transferrin, however, has been shown to have a high positive predictive value. It has also been noted to be characterized by unilateral discharge.

It is a sign of basal skull fracture. Management includes watchful waiting - leaks often stop spontaneously; if this does not occur then neurosurgical closure is necessary to prevent the spread of infection to the meninges.

Other signs of basal skull fracture includes CSF otorrhoea (drainage of CSF through the ear). It can have devastating complications in some patients, as the communication between the nasal cavity and the cerebrospinal fluid and CNS can result in bacterial infections of the CNS that can have catastrophic effects on the patient.

CSF rhinorrhoea can also be a symptom of a pituitary adenoma.

See also

• traumatic head injury
• meningitis
• cerebrospinal fluid
• Beta-2 transferrin

References

UpToDate Contents

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• 1. 鼻炎の概要 an overview of rhinitis
• 2. 特発性低髄液圧性頭痛の病態生理、臨床的特徴、および診断 pathophysiology clinical features and diagnosis of spontaneous low cerebrospinal fluid pressure headache
• 3. 成人における頭蓋骨骨折 skull fractures in adults
• 4. 小児における頭蓋骨骨折 skull fractures in children
• 5. 成人における顔面外傷 facial trauma in adults

English Journal

• A case of sphenoid sinus meningoencephalocele repaired by an image-guided endoscopic endonasal approach.

• Sano H, Matsuwaki Y, Kaito N, Joki T, Okushi T, Moriyama H.SourceDepartment of Otorhinolaryngology, Jikei University School of Medicine, Tokyo, Japan.
• Auris, nasus, larynx.Auris Nasus Larynx.2011 Oct;38(5):632-7. Epub 2011 Mar 9.
• We report a Japanese patient with a complaint of unilateral watery nasal discharge. Analysis of the nasal discharge showed it to contain high levels of sugar and transferrin, which indicated cerebrospinal fluid (CSF) rhinorrhea. A diagnosis of sphenoid sinus meningoencephalocele was easily made on t
• PMID 21392906

• Spontaneous cerebrospinal fluid rhinorrhea as the initial presentation of growth hormone-secreting pituitary adenoma.

• Makin V, Hatipoglu B, Hamrahian AH, Arrossi AV, Knott PD, Lee JH, Sade B.SourceDepartment of Endocrinology, Endocrinology and Metabolism Institute, Cleveland, OH, USA.
• American journal of otolaryngology.Am J Otolaryngol.2011 Sep-Oct;32(5):433-7. Epub 2010 Oct 2.
• Patients with acromegaly usually present with characteristic clinical features or comorbidities associated with excess insulinlike growth factor 1 (IGF-1)/growth hormone (GH) or may come to medical attention secondary to mass effects causing visual field distortions. Herein, we report a case of spon
• PMID 20888068

Japanese Journal

• Simultaneous Occurrence of Subarachnoid Hemorrhage and Epistaxis Due to Ruptured Petrous Internal Carotid Artery Aneurysm: Association With Transsphenoidal Surgery and Radiation Therapy : —Case Report—

• ENDO Hidenori,FUJIMURA Miki,INOUE Takashi,MATSUMOTO Yasushi,OGAWA Yoshikazu,KAWAGISHI Jun,JOKURA Hidefumi,SHIMIZU Hiroaki,TOMINAGA Teiji
• Neurologia medico-chirurgica 51(3), 226-229, 2011
• … the patient did not develop symptomatic vasospasm, recurrent epistaxis, or cerebrospinal fluid rhinorrhea. …
• NAID 130000677033

• Purely Endoscopic Repair of Traumatic Cerebrospinal Fluid Rhinorrhea From the Anterior Skull Base : —Case Report—

• KOMATSU Mika,KOMATSU Fuminari,CAVALLO Luigi M.,SOLARI Domenico,STAGNO Vita,INOUE Tooru,CAPPABIANCA Paolo
• Neurologia medico-chirurgica 51(3), 222-225, 2011
• … A 38-year-old woman presented with a case of post-traumatic ethmoidal cerebrospinal fluid (CSF) leak that was repaired using a purely endoscopic endonasal approach. … The patient was discharged without clinical evidence of CSF rhinorrhea and no leaks were apparent at the 3-month follow-up clinical and radiological examinations. … Post-traumatic CSF rhinorrhea occurs in cases of dural tears associated with small bone breaks, most frequently involving the anterior skull base. …
• NAID 130000677032

Related Links

• CSF Rhinorrhea - eMedicine - Medscape

22 Jul 2011 ... Disruption of the barriers between the sinonasal cavity and the anterior and middle cranial fossae can lead to the discharge of cerebrospinal fluid (CSF) into the nasal cavity.

Related Pictures

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★リンクテーブル★

リンク元	「髄液鼻漏」
関連記事	「flu」「cerebrospinal」「fluid」

「髄液鼻漏」

　　[★]

英

cerebrospinal fluid rhinorrhea, CSF rhinorrhea

「flu」

　　[★]

• インフルエンザ

関

grippe、influenza

　

「cerebrospinal」

　　[★]

• adj.

• 脳脊髄の

関

craniospinal

　

「fluid」

　　[★]

同

BALF