English Journal

Na (+) /Ca (2+) Exchanger 3 is Downregulated in the Hippocampus and Cerebrocortex of Rats with Hyperthermia-induced Convulsion.

Sun D, Xiao JH, Bai Y1, Chen MS, Hu JS, Wu GF, Mao B, Wu SH, Hu Y.
Chinese medical journal.Chin Med J (Engl).2015 Nov 20;128(22):3083-7. doi: 10.4103/0366-6999.169103.
BACKGROUND: Na + /Ca 2+ exchanger (NCX) plays a crucial role in pentylenetetrazol-induced convulsion. However, it is unclear whether NCX is critically involved in hyperthermia-induced convulsion. In this study, we examined the potential changes in NCX3 in the hippocampus and cerebrocortex of rats wi
PMID 26608990

[Change of memory function and decrease of nitric oxide level of whole brain in the transgenic mice expressing human tau 40 with P301L mutation].

Gao IW, Yu LX, Hong Y, Niu C, Chen Y, Wang XL, Chen RZ, Wang Hai.
Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology.Zhongguo Ying Yong Sheng Li Xue Za Zhi.2015 Sep;31(5):385-9.
OBJECTIVE: To study the mechanism of learning and memory dysfuction in the transgenic mouse expressing human tau 40 isoform with P301L mutation (F10).METHODS: The human tau protein expression and phosphor-tau protein levels were detected with Western blot method. The neurofibrillary tangles were obs
PMID 26827524

Oxygen-sensitive reduction in Ca²⁺-activated K⁺ channel open probability in turtle cerebrocortex.

Rodgers-Garlick CI1, Hogg DW, Buck LT.
Neuroscience.Neuroscience.2013 May 1;237:243-54. doi: 10.1016/j.neuroscience.2013.01.046. Epub 2013 Feb 4.
In response to low ambient oxygen levels the western painted turtle brain undergoes a large depression in metabolic rate which includes a decrease in neuronal action potential frequency. This involves the arrest of N-methyl-D-aspartate receptor (NMDAR) and α-amino-3-hydroxy-5-methylisoxazole-4-prop
PMID 23384611