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1. 変形性関節症の初回薬物療法 initial pharmacologic therapy of osteoarthritis
2. 過敏性腸症候群に対するアロセトロン塩酸塩（Lotronex） alosetron hydrochloride lotronex for irritable bowel syndrome
3. 成人における急性咽頭炎の対症療法 symptomatic treatment of acute pharyngitis in adults
4. コーガン症候群 cogans syndrome
5. 局所麻酔剤に対するアレルギー反応 allergic reactions to local anesthetics

Zalewski P1, Skibiński R, Paczkowska M, Garbacki P, Talaczyńska A, Cielecka-Piontek J, Jelińska A.
Drug development and industrial pharmacy.Drug Dev Ind Pharm.2015 Jun 24:1-6. [Epub ahead of print]
The influence of pH on the stability of cefozopran hydrochloride (CZH) was investigated in the pH range of 0.44-13.00. Six degradation products were identified with a hybrid ESI-Q-TOF mass spectrometer. The degradation of CZH as a result of hydrolysis was a pseudo-first-order reaction. As general ac
PMID 26079426

DEVELOPMENT AND VALIDATION OF THE STABILITY-INDICATING LC-UV METHOD FOR DETERMINATION OF CEFOZOPRAN HYDROCHLORIDE.

Zalewski P, Garbacki P, Cielecka-Piontek J, Bednarek-Rajewska K, Krause A.
Acta poloniae pharmaceutica.Acta Pol Pharm.2015 May-Jun;72(3):423-7.
The stability-indicating LC assay method was developed and validated for quantitative determination of cefozopran hydrochloride (CZH) in the presence of degradation products formed during the forced degradation studies. An isocratic, RP-HPLC method was developed with C-18 (250 mm x 4.6 mm, 5 µm) co
PMID 26642650

Pharmacokinetics of cefozopran by single and multiple intravenous infusions in healthy Chinese volunteers.

Wu GL1, Shentu JZ, Zhou HL, Zhu MX, Hu XJ, Liu J, Wu LH.
Drugs in R&D.Drugs R D.2015 Mar;15(1):63-70. doi: 10.1007/s40268-014-0075-3.
BACKGROUND AND OBJECTIVES: Cefozopran is a parenteral cephalosporin with a broad spectrum of activity against Gram-positive and Gram-negative bacteria. The objective of this study was to evaluate the pharmacokinetics of cefozopran after single- and multiple-dose intravenous administration in healthy
PMID 25644122