関: cefminox sodium

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/12/29 09:06:11」(JST)

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Cefminox (INN) is a second-generation cephalosporin antibiotic.^[1]^[2]

Spectrum of Bacterial Susceptibility and Resistance[edit]

Fusobacterium necrophorum are generally susceptible to Cefminox, while Actinomyces spp, Bacteroides vulgatus and Pseudomonas aeruginosa are resistant to Cefminox. Clostridium sordellii, Porphyromonas asaccharolytica and Prevotella oralis have developed resistance to Cefminox to varying degrees.For the detailed minimum inhibition concentration information, please refer to Cefminox Susceptibility and Resistance Data sheet.^[3]

References[edit]

^ Torres, A. J.; Valladares, L. D.; Jover, J. M.; Sánchez-Pernaute, A.; Frías, J.; Carcas, A. J.; Coronel, P.; Ródenas, E.; Pérez-Balcabao, I.; Fernández-Roblas, R.; Moreno, M.; Balibrea, J. L. (2000). "Cefminox versus metronidazole plus gentamicin intra-abdominal infections: A prospective randomized controlled clinical trial". Infection 28 (5): 318–322. doi:10.1007/s150100070027. PMID 11073141. edit
^ Patentdocs: Reaction Medium For Methicillin-Resistant Staphylococcus Aureus (Mrsa) Bacteria
^ "Cefminox Susceptibility and Resistance Data". Retrieved 10 April 2013.

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English Journal

The Meaningful Use of EMR in Chinese Hospitals: A Case Study on Curbing Antibiotic Abuse.

Li JS, Zhang XG, Wang HQ, Wang Y, Wang JM, Shao QD.SourceHealthcare Informatics Engineering Research Center, Zhejiang University, Hangzhou, 310027, China, ljs@zju.edu.cn.
Journal of medical systems.J Med Syst.2013 Apr;37(2):9937. doi: 10.1007/s10916-013-9937-4. Epub 2013 Mar 14.
Comprehensive electronic medical records (EMR) have proven to be an effective tool for improving the safety and quality of healthcare. In particular, EMR has resulted in a significant reduction in antibiotic consumption and an improvement in rational antibiotic use. This study focused on evaluating
PMID 23494391

Correlation between cephamycin consumption and the incidence of antimicrobial resistance in Acinetobacter baumannii at a university hospital in China from 2001 to 2009.

Song W, Cao J, Mei YL.SourceRespiratory Department, the first affiliated hospital with Nanjing Medical University, China.
International journal of clinical pharmacology and therapeutics.Int J Clin Pharmacol Ther.2011 Dec;49(12):765-71.
OBJECTIVES: To investigate the correlation between cephamycin consumption and the prevalence of antimicrobial resistance in Acinetobacter baumannii.METHODS: Cephamycins consumption was expressed as defined daily dose (DDD) per 1,000 patient days by World Health Organization (WHO) Anatomical Therapeu
PMID 22122819

Simultaneous determination of aminomethylbenzoic acid, cefminox sodium and etamsylate in human urine by capillary electrophoresis.

Sun H, Wei L, Wu Y, Liu N.SourceCollege of Chemistry and Environmental Science, Hebei University, Key Laboratory of Analytical Science and Technology of Hebei Province, Baoding, 071002, China. hanwen@hbu.edu.cn
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.J Chromatogr B Analyt Technol Biomed Life Sci.2010 Jul 1;878(21):1899-903. doi: 10.1016/j.jchromb.2010.05.017. Epub 2010 May 24.
A sensitive and selective capillary electrophoresis method is developed, for the first time, for effective separation and simultaneous determination of aminomethylbezoic acid (PAMBA), cefminox sodium (CMNX) and etamsylate (ETM). The electrophoresis conditions were investigated and optimized. A 25 mM
PMID 20570576

Japanese Journal

生産を志向した新規合成反応の開発研究 : セファロスポリンの新規7α-メトキシ化反応開発を例として

村井安,渥美國夫
有機合成化学協会誌 69(5), 571-578, 2011-05-01
… The synthetic route was adopted for the industrial process of cefminox, a cephamycin-group antibiotic, which had been developed by Meiji Seika Kaisha and was launched in 1987. …
NAID 10028293687

Simultaneous determination of aminomethylbenzoic acid, cefminox sodium and etamsylate in human urine by capillary electrophoresis

SUN Hanwen,WEI Lijing,WU Yuanyuan,LIU Na
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 878(21), 1899-1903, 2010-07-01
NAID 10028038760

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★リンクテーブル★

リンク元	「セフミノクス」
拡張検索	「cefminox sodium」

「セフミノクス」

Cefminox
Systematic (IUPAC) name
	(6R,7S)-7-(((((2S)-2-amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid
Clinical data
AHFS/Drugs.com	International Drug Names
Legal status	℞ Prescription only
Routes	IM, IV
Identifiers
CAS number	84305-41-9
ATC code	J01DC12
PubChem	CID 71141
ChemSpider	64286
UNII	PW08Y13465
KEGG	D07642
Chemical data
Formula	C16H21N7O7S3
Mol. mass	519.57 g/mol
	SMILES O=C2N1/C(=C(\CS[C@@H]1[C@]2(OC)NC(=O)CSC[C@H](C(=O)O)N)CSc3nnnn3C)C(=O)O;
	InChI InChI=1S/C16H21N7O7S3/c1-22-15(19-20-21-22)33-4-7-3-32-14-16(30-2,13(29)23(14)10(7)12(27)28)18-9(24)6-31-5-8(17)11(25)26/h8,14H,3-6,17H2,1-2H3,(H,18,24)(H,25,26)(H,27,28)/t8-,14-,16+/m1/s1 ; Key:JSDXOWVAHXDYCU-VXSYNFHWSA-N ;
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