WordNet

a silvery soft waxy metallic element of the alkali metal group; occurs abundantly in natural compounds (especially in salt water); burns with a yellow flame and reacts violently in water; occurs in sea water and in the mineral halite (rock salt) (同)Na, atomic number 11

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Carinatumins A-C, new alkaloids from Lycopodium carinatum inhibiting acetylcholinesterase.

Choo CY, Hirasawa Y, Karimata C, Koyama K, Sekiguchi M, Kobayashi J, Morita H.SourceFaculty of Pharmaceutical Sciences, Hoshi University, Shinagawa-ku, Tokyo 142-8501, Japan.
Bioorganic & medicinal chemistry.Bioorg Med Chem.2007 Feb 15;15(4):1703-7. Epub 2006 Dec 15.
Three new Lycopodium alkaloids, carinatumins A-C (1-3), have been isolated from the club moss Lycopodium carinatum. Structures and stereochemistry of 1-3 were elucidated on the basis of 2D NMR correlations. Carinatumins A (1) and B (2) exhibited a potent inhibitory activity against acetylcholinester
PMID 17188496

Role of the monocarboxylic acid transport system in the intestinal absorption of an orally active beta-lactam prodrug: carindacillin as a model.

Li YH, Tanno M, Itoh T, Yamada H.SourceSchool of Pharmaceutical Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo, Japan.
International journal of pharmaceutics.Int J Pharm.1999 Nov 30;191(2):151-9.
Transport of carbenicillin (CBPC) and its orally active prodrug (carindacillin, CIPC) was studied with rat intestinal brush border membrane vesicles (BBMV). CIPC was transported uphill into BBMV in the presence of a H(+) gradient, indicating that CIPC absorption is carrier-mediated. Indeed, CIPC was
PMID 10564841

Mechanism of intestinal absorption of an orally active beta-lactam prodrug: uptake and transport of carindacillin in Caco-2 cells.

Li YH, Ito K, Tsuda Y, Kohda R, Yamada H, Itoh T.SourceSchool of Pharmaceutical Sciences, Kitasato University, Minato-ku, Tokyo, Japan.
The Journal of pharmacology and experimental therapeutics.J Pharmacol Exp Ther.1999 Sep;290(3):958-64.
Absorption characteristics of carindacillin (CIPC) were investigated using Caco-2 cells, and the results were compared with those of its parent drug, carbenicillin (CBPC). Uptake of CBPC was not affected by the metabolic inhibitor or the change in extracellular pH. CBPC appeared to be taken up into
PMID 10454465