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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2012/08/10 23:13:53」(JST)

Carindacillin (INN), also known as Carbenicillin indanyl (USAN) is a penicillin antibiotic. It is a prodrug of carbenicillin.^[1]

It is administered orally, as the sodium salt. It is marketed by Pfizer under the brand name Geocillin.

References

^ English AR, Retsema JA, Ray VA, Lynch JE (March 1972). "Carbenicillin indanyl sodium, an orally active derivative of carbenicillin". Antimicrob. Agents Chemother. 1 (3): 185–91. PMC 444190. PMID 4558137. http://aac.asm.org/cgi/pmidlookup?view=long&pmid=4558137.

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Kruckenhauser EM1, Nogler M1, Coraça-Huber D1.
Drug research.Drug Res (Stuttg).2014 Mar;64(3):166-8. doi: 10.1055/s-0033-1354367. Epub 2013 Aug 28.
OBJECTIVE: Lavage techniques are used every day all over the world to clean wounds and surgical approaches. The solutions used vary depending on the application range; there are, for instance, normal saline, antibiotic or antiseptic solutions. This review describes the lavage solutions actually used
PMID 23986306

Carinatumins A-C, new alkaloids from Lycopodium carinatum inhibiting acetylcholinesterase.

Choo CY1, Hirasawa Y, Karimata C, Koyama K, Sekiguchi M, Kobayashi J, Morita H.
Bioorganic & medicinal chemistry.Bioorg Med Chem.2007 Feb 15;15(4):1703-7. Epub 2006 Dec 15.
Three new Lycopodium alkaloids, carinatumins A-C (1-3), have been isolated from the club moss Lycopodium carinatum. Structures and stereochemistry of 1-3 were elucidated on the basis of 2D NMR correlations. Carinatumins A (1) and B (2) exhibited a potent inhibitory activity against acetylcholinester
PMID 17188496

Role of the monocarboxylic acid transport system in the intestinal absorption of an orally active beta-lactam prodrug: carindacillin as a model.

Li YH1, Tanno M, Itoh T, Yamada H.
International journal of pharmaceutics.Int J Pharm.1999 Nov 30;191(2):151-9.
Transport of carbenicillin (CBPC) and its orally active prodrug (carindacillin, CIPC) was studied with rat intestinal brush border membrane vesicles (BBMV). CIPC was transported uphill into BBMV in the presence of a H(+) gradient, indicating that CIPC absorption is carrier-mediated. Indeed, CIPC was
PMID 10564841

Mechanism of intestinal absorption of an orally active β-lactam prodrug : uptake and transport of carindacillin in Caco-2 cells

リンク元	「カリンダシリン」
拡張検索	「carindacillin sodium」

Carindacillin
Systematic (IUPAC) name
	(2S,5R,6R)-6-([3-(2,3-dihydro-1H-inden-5-yloxy)-3-oxo-2-phenylpropanoyl]amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	?
Legal status	℞ Prescription only
Routes	Oral
Identifiers
CAS number	26605-69-6
ATC code	J01CA05
PubChem	CID 93184
ChemSpider	391995
UNII	5V278481KE
Chemical data
Formula	C26H26N2O6S
Mol. mass	494.55 g/mol
	SMILES [Na+].O=C([O-])[C@@H]4N5C(=O)[C@@H](NC(=O)C(c1ccccc1)C(=O)Oc2cc3c(cc2)CCC3)[C@H]5SC4(C)C;