出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/10/22 09:44:32」(JST)
Systematic (IUPAC) name | |
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(3S)-3,6-diamino-N-[[(2S,5S,8E,11S,15S)-15-amino-11-[(4R)-2-amino-3,4,5,6-tetrahydropyrimidin-4-yl]-8-[(carbamoylamino)methylidene]-2-(hydroxymethyl)-3,6,9,12,16-pentaoxo-1,4,7,10,13-pentazacyclohexadec-5-yl]methyl]hexanamide; (3S)-3,6-diamino-N-[[(2S,5S,8E,11S,15S)-15-amino-11-[(4R)-2-amino-3,4,5,6-tetrahydropyrimidin-4-yl]-8-[(carbamoylamino)methylidene]-2-methyl-3,6,9,12,16-pentaoxo-1,4,7,10,13-pentazacyclohexadec-5-yl]methyl]hexanamide | |
Clinical data | |
AHFS/Drugs.com | monograph |
MedlinePlus | a682860 |
Pregnancy cat. | ? |
Legal status | ? |
Identifiers | |
CAS number | 11003-38-6 Y |
ATC code | J04AB30 |
PubChem | CID 3032400 |
DrugBank | DB00314 |
ChemSpider | 21106276 Y |
UNII | 232HYX66HC Y |
KEGG | D00135 N |
ChEMBL | CHEMBL1201252 N |
NIAID ChemDB | 007653 |
Chemical data | |
Formula | C25H44N14O8 |
Mol. mass | 668.706 g/mol |
InChI
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N (what is this?) (verify) |
Capreomycin is a peptide antibiotic, commonly grouped with the aminoglycosides, which is given in combination with other antibiotics for MDR-tuberculosis. Adverse effects include nephrotoxicity and 8th cranial auditory vestibular nerve nerve toxicity.
The drug should not be given with streptomycin or other drugs that may damage the auditory vestibular nerve. Patients on this drug will often require audiology tests.
It is a cyclic peptide. Capreomycin is administered intramuscularly and shows bacteriostatic activity. [1]
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リンク元 | 「カプレオマイシン」「CPRM」 |
拡張検索 | 「capreomycin sulfate」 |
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