関: alginate、alginic acid、sodium alginate

WordNet

a white metallic element that burns with a brilliant light; the fifth most abundant element in the earths crust; an important component of most plants and animals (同)Ca, atomic number 20

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『カルシウム』(金属元素;化学記号は『Ca』)

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2018/08/17 13:12:30」(JST)

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Calcium alginate is a water-insoluble, gelatinous, cream-coloured substance that can be created through the addition of aqueous calcium chloride to aqueous sodium alginate. Calcium alginate is also used for entrapment of enzymes and forming artificial seeds in plant tissue culture.

"Alginate" is usually the salts of alginic acid, but it can also refer to derivatives of alginic acid and alginic acid itself; in some publications the term "algin" is used instead of alginate. Alginate is present in the cell walls of brown algae, as the calcium, magnesium and sodium salts of alginic acid.

Preparation

Extraction of alginate

To extract the alginate, the seaweed is broken into pieces and stirred with a hot solution of an alkali, usually sodium carbonate. Over a period of about two hours, the alginate dissolves as sodium alginate to give a very thick slurry. This slurry also contains the part of the seaweed that does not dissolve, mainly cellulose. This insoluble residue must be removed from the solution. The solution is too thick (viscous) to be filtered and must be diluted with a very large quantity of water. After dilution, the solution is forced through a filter cloth in a filter press. However, the pieces of undissolved residue are very fine and can quickly clog the filter cloth. Therefore, before filtration is started, a filter aid, such as diatomaceous earth, must be added; this holds most of the fine particles away from the surface of the filter cloth and facilitates filtration. However, filter aid is expensive and can make a significant contribution to costs. To reduce the quantity of filter aid needed, some processors force air into the extract as it is being diluted with water (the extract and diluting water are mixed in an in-line mixer into which air is forced). Fine air bubbles attach themselves to the particles of residue. The diluted extract is left standing for several hours while the air rises to the top, taking the residue particles with it. This frothy mix of air and residue is removed from the top and the solution is withdrawn from the bottom and pumped to the filter.

Preparation of calcium alginate

The goal of the extraction process is to obtain dry, powdered, sodium alginate. The calcium and magnesium salts do not dissolve in water; the sodium salt does. The rationale behind the extraction of alginate from the seaweed is to convert all the alginate salts to the sodium salt, dissolve this in water, and remove the seaweed residue by filtration. The alginate must then be recovered from the aqueous solution. The solution is very dilute and evaporation of the water is not economic. To the sodium alginate from the initial extraction solution, a calcium salt is added. This causes calcium alginate to form with a fibrous texture; it does not dissolve in water and can be separated from it with relative ease using a metal screen.

Uses

Uses of calcium alginate are:

in plant tissue culture to produce insoluble artificial seeds
for immobilizing enzymes by entrapment
to produce an edible substance
incorporated into wound dressings (alginate dressings) as a hemostatic
sustain drug delivery system

References

^ Gosselin, R.E.; H.C. Hodge; R.P. Smith & M.N. Gleason (1976). Clinical Toxicology of Commercial Products (4th ed.). Baltimore: Williams and Wilkins. p. II-155.

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★リンクテーブル★

リンク元	「sodium alginate」「アルギン酸カルシウム」「alginic acid」
関連記事	「alginate」「calcium」

「sodium alginate」

Calcium alginate
Names
	IUPAC name Calcium β-D-mannopyranuronosyl-(1→4)- α-L-gulopyranuronosyl-(1→4)- α-L-gulopyranuronate
	Other names E404
Identifiers
CAS Number	9005-35-0;
ChemSpider	24589538;
ECHA InfoCard	100.124.785
E number	E404 (thickeners, ...)
UNII	8P20S56HZI;
Properties
Chemical formula	(C12H14CaO12)n
Appearance	Solid
Pharmacology
ATC code	B02BC08 (WHO)
Hazards
	Lethal dose or concentration (LD, LC):
LD50 (median dose)	>15g/kg
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
	Infobox references