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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/06/13 15:04:38」(JST)

Bendazac (or bendazolic acid) is a non-steroidal anti-inflammatory drug used for joint and muscular pain.

References

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Synthesis and biological evaluations of novel bendazac lysine analogues as potent anticataract agents.

Shen H, Gou S, Shen J, Zhu Y, Zhang Y, Chen X.SourceSchool of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, PR China.
Bioorganic & medicinal chemistry letters.Bioorg Med Chem Lett.2010 Apr 1;20(7):2115-8. Epub 2010 Feb 19.
Novel bendazac analogues and their salts have been designed and prepared. The resulting compounds (13c-d, 15c, 17c) showed very good aqueous solubility (>100 mg/mL). An in vitro assay showed that most of the resulting compounds had potent protective activity against the oxidative damage. Particul
PMID 20223660

Gene expression profiling in rat liver treated with compounds inducing elevation of bilirubin.

Hirode M, Horinouchi A, Uehara T, Ono A, Miyagishima T, Yamada H, Nagao T, Ohno Y, Urushidani T.SourceDevelopment Research Center, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Yodogawa-ku, Osaka, Japan. Hirode_Mitsuhiro@takeda.co.jp
Human & experimental toxicology.Hum Exp Toxicol.2009 Apr;28(4):231-44.
We have constructed a large-scale transcriptome database of rat liver treated with various drugs. In an effort to identify a biomarker for the diagnosis of elevated total bilirubin (TBIL) and direct bilirubin (DBIL), we extracted 59 probe sets of rat hepatic genes from the data for seven typical dru
PMID 19734275

Inhibition of Protein Denaturation by Fatty Acids, Bile Salts and Other Natural Substances : A New Hypothesis for the Mechanism of Action of Fish Oil in Rheumatic Diseases

SASO Luciano,VALENTINI Giovanni,CASINI Maria Luisa,MATTEI Eleonora,BRAGHIROLI Laura,MAZZANTI Gabriela,PANZIRONI Claudio,GRIPPA Eleonora,SILVESTRINI Bruno
The Japanese journal of pharmacology 79(1), 89-99, 1999-01
… (1 ml/kg) in the rat, protected ex vivo (after 2 hr) serum against heat-induced denaturation more than bendazac, a known antidenaturant drug. … In this connection, it is of note that the in vitro antidenaturant activity of fish oil fatty acids was higher than that of known antidenaturant drugs such as bendazac and bindarit and nonsteroidal anti-inflammatory drugs like phenylbutazone and indomethacin which could exert beneficial effects in chronic inflammatory conditions by stabilizing endogenous proteins. …
NAID 10008194251

Bendazac lysine. A review of its pharmacological properties and therapeutic potential in the management of cataracts

リンク元	「ベンダザック」「bendazolic acid」

Bendazac
Systematic (IUPAC) name
	[(1-benzyl-1H-indazol-3-yl)oxy]acetic acid
Clinical data
AHFS/Drugs.com	International Drug Names
Routes of; administration	Topical
Identifiers
CAS Registry Number	20187-55-7
ATC code	M02AA11 S01BC07
PubChem	CID: 2313
ChemSpider	2223
UNII	G4AG71204O
KEGG	D01594
ChEBI	CHEBI:31257
ChEMBL	CHEMBL1089221
Chemical data
Formula	C16H14N2O3
Molecular mass	282.294 g/mol
	SMILES O=C(O)COc2nn(c1ccccc12)Cc3ccccc3;
	InChI InChI=1S/C16H14N2O3/c19-15(20)11-21-16-13-8-4-5-9-14(13)18(17-16)10-12-6-2-1-3-7-12/h1-9H,10-11H2,(H,19,20) ; Key:BYFMCKSPFYVMOU-UHFFFAOYSA-N ;
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