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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/10/19 01:34:36」(JST)
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Bekanamycin
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Systematic (IUPAC) name |
(2S,3R,4S,5S,6R)-4-amino-2-{[(2S,3R,4S,6R)-4,6-diamino-3-{[(2R,3R,4R,5S,6R)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}-6-(hydroxymethyl)oxane-3,5-diol
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Clinical data |
AHFS/Drugs.com |
International Drug Names |
Legal status |
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Identifiers |
CAS Registry Number |
4696-76-8 N |
ATC code |
J01GB13 |
PubChem |
CID: 439318 |
ChemSpider |
388449 Y |
UNII |
15JT14C3GI Y |
ChEBI |
CHEBI:28098 Y |
ChEMBL |
CHEMBL176 Y |
NIAID ChemDB |
005087 |
Chemical data |
Formula |
C18H37N5O10 |
Molecular mass |
483.51 g/mol |
SMILES
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C1[C@@H]([C@H]([C@@H]([C@H]([C@@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)N)O)O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CN)O)O)N)N
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InChI
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InChI=1S/C18H37N5O10/c19-2-6-11(26)12(27)9(23)17(30-6)32-15-4(20)1-5(21)16(14(15)29)33-18-13(28)8(22)10(25)7(3-24)31-18/h4-18,24-29H,1-3,19-23H2/t4-,5+,6+,7+,8-,9+,10+,11+,12+,13+,14-,15+,16-,17+,18+/m0/s1 Y
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Key:SKKLOUVUUNMCJE-FQSMHNGLSA-N Y
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N (what is this?) (verify) |
Bekanamycin (INN, or kanamycin B) is an aminoglycoside antibiotic.[1]
References
- ^ Morales, M. A.; Castrillon, J. L.; Hernandez, D. A. (1993). "Effects of bekanamycin and dibekacin on the electrical activity of cardiac pacemaker cells". Archives of medical research 24 (4): 339–345. PMID 8118157.
Antibacterials: protein synthesis inhibitors (J01A, J01B, J01F, J01G, QJ01XQ)
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30S |
Aminoglycosides
(initiation inhibitors) |
-mycin (Streptomyces) |
- Streptomycin#
- Dihydrostreptomycin
- Neomycin#
- Framycetin
- Paromomycin
- Ribostamycin
- Kanamycin#
- Amikacin
- Arbekacin
- Bekanamycin
- Dibekacin
- Tobramycin
- Spectinomycin#
- Hygromycin B
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-micin (Micromonospora) |
- Gentamicin#
- Netilmicin
- Sisomicin
- Isepamicin
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Tetracycline antibiotics
(tRNA binding) |
Tetracyclines |
- Doxycycline#
- Chlortetracycline
- Clomocycline
- Demeclocycline
- Lymecycline
- Meclocycline
- Metacycline
- Minocycline
- Oxytetracycline
- Penimepicycline
- Rolitetracycline
- Tetracycline
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Glycylcyclines |
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50S |
Oxazolidinone
(initiation inhibitors) |
- Eperezolid
- Linezolid
- Posizolid
- Radezolid
- Ranbezolid
- Sutezolid
- Tedizolid
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Peptidyl transferase |
Amphenicols |
- Chloramphenicol#
- Azidamfenicol
- Thiamphenicol
- Florfenicol
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Pleuromutilins |
- Retapamulin
- Tiamulin
- Valnemulin
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MLS (transpeptidation/translocation) |
Macrolides |
- Azithromycin#
- Clarithromycin
- Dirithromycin
- Erythromycin#
- Flurithromycin
- Josamycin
- Midecamycin
- Miocamycin
- Oleandomycin
- Rokitamycin
- Roxithromycin
- Spiramycin
- Troleandomycin
- Tylosin
- Ketolides
- Telithromycin
- Cethromycin
- Solithromycin†
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Lincosamides |
- Clindamycin#
- Lincomycin
- Pirlimycin
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Streptogramins |
- Pristinamycin
- Quinupristin/dalfopristin
- Virginiamycin
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EF-G |
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- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
Index of bacterial disease
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Description |
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Disease |
- Gram-positive firmicutes
- Gram-positive actinobacteria
- Gram-negative proteobacteria
- Gram-negative non-proteobacteria
- Cholera
- Tuberculosis
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Treatment |
- Antibiotics
- cell wall
- nucleic acid
- mycobacteria
- protein synthesis
- other
- Antibodies
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English Journal
- HPLC-ELSD determination of kanamycin B in the presence of kanamycin A in fermentation broth.
- Zhang Y1, He HM, Zhang J, Liu FJ, Li C, Wang BW, Qiao RZ.
- Biomedical chromatography : BMC.Biomed Chromatogr.2015 Mar;29(3):396-401. doi: 10.1002/bmc.3289. Epub 2014 Jul 17.
- A novel method for the direct determination of kanamycin B in the presence of kanamycin A in fermentation broth using high performance liquid chromatography with evaporative light scattering detector (HPLC-ELSD) was developed. An Agilent Technologies C18 column was utilized, evaporation temperature
- PMID 25042110
- A real-time fluorescence polarization activity assay to screen for inhibitors of bacterial ribonuclease P.
- Liu X1, Chen Y1, Fierke CA2.
- Nucleic acids research.Nucleic Acids Res.2014 Nov 10;42(20):e159. doi: 10.1093/nar/gku850. Epub 2014 Sep 23.
- Ribonuclease P (RNase P) is an essential endonuclease that catalyzes the 5' end maturation of precursor tRNA (pre-tRNA). Bacterial RNase P is an attractive potential antibacterial target because it is essential for cell survival and has a distinct subunit composition compared to the eukaryal counter
- PMID 25249623
- Chemical interrogation of drug/RNA complexes: from chemical reactivity to drug design.
- Jiménez-Moreno E1, Gómez-Pinto I, Corzana F, Santana AG, Revuelta J, Bastida A, Jiménez-Barbero J, González C, Asensio JL.
- Angewandte Chemie (International ed. in English).Angew Chem Int Ed Engl.2013 Mar 11;52(11):3148-51. doi: 10.1002/anie.201209434. Epub 2013 Feb 7.
- PMID 23401341
Related Links
- Bekanamycin is a medicine available in a number of countries worldwide. A list of US medications equivalent to Bekanamycin is available on the Drugs.com website. ... Drugs.com provides accurate and independent information on ...
- bekanamycin (uncountable) A particular aminoglycoside antibiotic. Retrieved from "https://en.wiktionary.org/w/index.php?title=bekanamycin&oldid=35156596" Categories: English lemmas English nouns English uncountable nouns ...
Related Pictures
★リンクテーブル★
[★]
- 英
- bekanamycin、bekanamycin sulfate
- 関
- 硫酸ベカナマイシン
[★]
- 関
- bekanamycin