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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/10/08 14:58:56」(JST)

Barnidipine (INN) is a calcium channel blocker.

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Perindopril and barnidipine alone or combined with simvastatin on hepatic steatosis and inflammatory parameters in hypertensive patients.

Derosa G1, Mugellini A2, Pesce RM2, D'Angelo A3, Maffioli P4.
European journal of pharmacology.Eur J Pharmacol.2015 Nov 5;766:31-6. doi: 10.1016/j.ejphar.2015.09.030. Epub 2015 Sep 25.
The aim of this study was to evaluate the effects of perindopril or barnidipine alone or combined with simvastatin on metabolic parameters and hepatic steatosis degree. One hundred and forty nine mild to moderate hypertensive, normocholesterolemic, overweight or obese outpatients with hepatic steato
PMID 26407654

Barnidipine ameliorates the vascular and renal injury in L-NAME-induced hypertensive rats.

Alp Yildirim FI1, Eker Kizilay D2, Ergin B3, Balci Ekmekçi Ö4, Topal G2, Kucur M4, Demirci Tansel C3, Uydeş Doğan BS2.
European journal of pharmacology.Eur J Pharmacol.2015 Oct 5;764:433-42. doi: 10.1016/j.ejphar.2015.07.033. Epub 2015 Jul 14.
The present study was aimed to investigate the influence of Barnidipine treatment on early stage hypertension by determining the function and morphology of the mesenteric and renal arteries as well as the kidney in N(ω)-Nitro-L-Arginine Methyl Ester (L-NAME)-induced hypertensive rats. Barnidipine (
PMID 26187312

Comparison of the effects of barnidipine+losartan compared with telmisartan+hydrochlorothiazide on several parameters of insulin sensitivity in patients with hypertension and type 2 diabetes mellitus.

Derosa G1,2, Querci F3, Franzetti I4, Dario Ragonesi P5, D'Angelo A1, Maffioli P1,6.
Hypertension research : official journal of the Japanese Society of Hypertension.Hypertens Res.2015 Oct;38(10):690-4. doi: 10.1038/hr.2015.57. Epub 2015 May 21.
The aim of this study was to evaluate the effects of barnidipine+losartan compared with telmisartan+hydrochlorothiazide on several parameters of insulin sensitivity in patients with hypertension and type 2 diabetes mellitus. We enrolled 148 normocholesterolemic patients with mild-to-moderate hyperte
PMID 25994603

リンク元	「バルニジピン」
拡張検索	「barnidipine hydrochloride」

Barnidipine
Systematic (IUPAC) name
	3-(3R)-1-benzylpyrrolidin-3-yl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	104713-75-9
ATC code	C08CA12
PubChem	CID 443869
ChemSpider	391959
UNII	2VBY96ASWJ
Chemical data
Formula	C27H29N3O6
Mol. mass	491.53 g/mol
	SMILES [O-][N+](=O)c1cccc(c1)[C@H]4C(/C(=O)OC)=C(\N\C(=C4\C(=O)O[C@H]3CCN(Cc2ccccc2)C3)C)C;
	InChI InChI=1S/C27H29N3O6/c1-17-23(26(31)35-3)25(20-10-7-11-21(14-20)30(33)34)24(18(2)28-17)27(32)36-22-12-13-29(16-22)15-19-8-5-4-6-9-19/h4-11,14,22,25,28H,12-13,15-16H2,1-3H3/t22-,25-/m0/s1 ; Key:VXMOONUMYLCFJD-DHLKQENFSA-N ;
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