bacteriostatic antibiotics

静菌的抗菌薬

WordNet

1. a chemical substance derivable from a mold or bacterium that can kill microorganisms and cure bacterial infections; "when antibiotics were first discovered they were called wonder drugs" (同)antibiotic drug
2. of or relating to antibiotic drugs
3. of or relating to or causing bacteriostasis
4. a chemical or biological material that inhibits bacterial growth

PrepTutorEJDIC

1. 抗生物質(ペニシリン,ストレプトマイシンなど) / 抗生[物質]の

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2017/03/28 01:06:43」(JST)

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[Wiki en表示]

A bacteriostatic agent or bacteriostat, abbreviated Bstatic, is a biological or chemical agent that stops bacteria from reproducing, while not necessarily killing them otherwise. Depending on their application, bacteriostatic antibiotics, disinfectants, antiseptics and preservatives can be distinguished. When bacteriostatic antimicrobials are used, the duration of therapy must be sufficient to allow host defense mechanisms to eradicate the bacteria. Upon removal of the bacteriostat, the bacteria usually start to grow again. This is in contrast to bactericides, which kill bacteria.

Bacteriostats are often used in plastics to prevent growth of bacteria on surfaces. Bacteriostats commonly used in laboratory work include sodium azide (which is acutely toxic) and thiomersal (which is a mutagen in mammalian cells).

Bacteriostatic antibiotics

Bacteriostatic antibiotics limit the growth of bacteria by interfering with bacterial protein production, DNA replication, or other aspects of bacterial cellular metabolism. They must work together with the immune system to remove the microorganisms from the body. However, there is not always a precise distinction between them and bactericidal antibiotics; high concentrations of some bacteriostatic agents are also bactericidal, whereas low concentrations of some bactericidal agents are bacteriostatic. This group includes:

• Chloramphenicol
• Clindamycin
• Ethambutol
• Lincosamides
• Macrolides
• Nitrofurantoin
• Novobiocin
• Oxazolidinone
• Spectinomycin
• Sulfonamides
• Tetracyclines
• Tigecycline
• Trimethoprim

See also

• List of antibiotics
• Oligodynamic effect

References

UpToDate Contents

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• 1. 細菌性肺炎の評価のための喀痰培養 sputum cultures for the evaluation of bacterial pneumonia
• 2. 皮膚の手技 dermatologic procedures
• 3. βラクタム系抗生物質の長期注入投与 prolonged infusions of beta lactam antibiotics
• 4. 細菌性心内膜炎に対する抗菌薬の予防投与 antimicrobial prophylaxis for bacterial endocarditis
• 5. β-ラクタム系抗生物質：作用機序、耐性および有害作用 beta lactam antibiotics mechanisms of action and resistance and adverse effects

English Journal

• Novel 3-substituted ocotillol-type triterpenoid derivatives as antibacterial candidates.

• Bi Y1, Ma C, Zhang H, Zhou Z, Yang J, Zhang Z, Meng Q, Lewis PJ, Xu J.
• Chemical biology & drug design.Chem Biol Drug Des.2014 Oct;84(4):489-96. doi: 10.1111/cbdd.12337. Epub 2014 May 20.
• Plant-derived triterpenoid saponins are involved in the plant defense system by targeting bacterial membranes. A series of ocotillol-type triterpenoid derivatives were synthesized starting from PPD, one of the main components of Panax ginseng and their antibacterial activity against several represen
• PMID 24811479

• Unanticipated Mycobacterium tuberculosis complex culture inhibition by immune modulators, immune suppressants, a growth enhancer, and vitamins A and D: clinical implications.

• Greenstein RJ1, Su L2, Shahidi A3, Brown WD2, Clifford A2, Brown ST4.
• International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.Int J Infect Dis.2014 Sep;26:37-43. doi: 10.1016/j.ijid.2014.01.026. Epub 2014 Jul 1.
• BACKGROUND: The development of novel antibiotics to treat multidrug-resistant (MDR) tuberculosis is time-consuming and expensive. Multiple immune modulators, immune suppressants, anti-inflammatories, and growth enhancers, and vitamins A and D, inhibit Mycobacterium avium subspecies paratuberculosis
• PMID 24998461

• In vitro activities of rifampin, colistin, sulbactam and tigecycline tested alone and in combination against extensively drug-resistant Acinetobacter baumannii.

• Dong X, Chen F, Zhang Y, Liu H, Liu Y, Ma L.
• The Journal of antibiotics.J Antibiot (Tokyo).2014 Aug 6. doi: 10.1038/ja.2014.99. [Epub ahead of print]
• The aim of this study was to investigate the in vitro activities of rifampin, colistin, sulbactam and tigecycline alone and in combination against extensively drug-resistant Acinetobacter baumannii (XDR-Ab). Twenty-five XDR-Ab strains were isolated from patients. Broth microdilution assay was used t
• PMID 25095805

Japanese Journal

• Bacteriostatic versus bactericidal activity of ciprofloxacin in Escherichia coli assessed by flow cytometry using a novel far-red dye

• SILVA Filomena,LOURENCO Olga,QUEIROZ Joao A,DOMINGUES Fernanda C
• Journal of antibiotics
• NAID 10030638641

• The Effect of a Cell-to-Cell Communication Molecule, Pseudomonas Quinolone Signal (PQS), Produced by P. aeruginosa on Other Bacterial Species

• Toyofuku Masanori,Nakajima-Kambe Toshiaki,Uchiyama Hiroo [他],NOMURA NOBUHIKO
• Microbes and environments 25(1), 1-7, 2010-03-01
• … In most cases, this effect differed from the bacteriostatic or bacteriolytic actions of antibiotics. …
• NAID 10025921415

• カルバペネム薬の目標>MIC値に関する臨床的検討

• 三鴨 廣繁,山岸 由佳,田中 香お里,渡邉 邦友
• The Japanese Journal of Antibiotics
• … 以上の結果は, カルバペネム薬でbacteriostatic effectを得るためのT>MIC目標値が20%以上とするCRAIG, W.A.やDRUSANO, G.L.らの報告を支持する結果であった。 …
• NAID 130004396077

Related Links

• Bacteriostatic agentとは - goo Wikipedia (ウィキペディア)

A bacteriostatic agent or bacteriostat, abbreviated Bstatic, is a biological or chemical agent that stops bacteria from reproducing, while not necessarily harming them otherwise. Depending on their application, bacteriostatic antibiotics, disinfectants ...

• Clinical Relevance of Bacteriostatic versus Bactericidal ...

Definition of Bacteriostatic/Bactericidal Activity The definitions of “bacteriostatic” and “bactericidal” appear to be straightforward: “bacteriostatic” means that the agent prevents the growth of bacteria (i.e., it keeps them in ...

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リンク元	「静菌的抗菌薬」
関連記事	「bacteriostatic」

「静菌的抗菌薬」

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英

bacteriostatic antibiotics

「bacteriostatic」

　　[★]

• adj.

• 静菌性の、静菌的な

関

bacteriostatically