Expression of neurofilaments and of a titin epitope in thymic epithelial tumors. Implications for the pathogenesis of myasthenia gravis.
Marx A1, Wilisch A, Schultz A, Greiner A, Magi B, Pallini V, Schalke B, Toyka K, Nix W, Kirchner T, Müller-Hermelink HK.
The American journal of pathology.Am J Pathol.1996 Jun;148(6):1839-50.
Autoantibodies against both striated muscle proteins, particularly titin, and the acetylcholine receptor are a hallmark of thymoma-associated myasthenia gravis. However, the stimulus for these responses remains enigmatic as whole titin is not detectable in these tumors. This study reports that in th
Antigen presentation by thymoma epithelial cells from myasthenia gravis patients to potentially pathogenic T cells.
Gilhus NE1, Willcox N, Harcourt G, Nagvekar N, Beeson D, Vincent A, Newsom-Davis J.
Journal of neuroimmunology.J Neuroimmunol.1995 Jan;56(1):65-76.
Thymomas associate strongly with myasthenia gravis (MG). We now show that cultured thymoma epithelial cells can present synthetic acetylcholine receptor (AChR) peptides to HLA-sharing responder T cell lines/clones nearly as efficiently as blood mononuclear cells. Responses depended strictly on the s
Looking for online definition of autosensitize in the Medical Dictionary? autosensitize explanation free. What is autosensitize? Meaning of autosensitize medical term. What does autosensitize mean? Autosensitize | definition of ...
au·to·sen·si·tize (aw'tō-sen'si-tīz), To sensitize against one's own body cells. Synonym(s): isosensitize ... Disclaimer All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for ...