フライ症候群。耳介側頭神経症候群
WordNet
- a pattern of symptoms indicative of some disease
- a complex of concurrent things; "every word has a syndrome of meanings"
PrepTutorEJDIC
- (疾患の徴候となる一群の)症徴候,症候群 / (事件・社会的状態などのパターンを示す)徴候形態
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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/06/03 17:53:45」(JST)
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Frey's syndrome |
Classification and external resources |
DiseasesDB |
29310 |
Frey's syndrome (also known as Baillarger’s syndrome, Dupuy’s syndrome, Auriculotemporal syndrome[1] or Frey-Baillarger syndrome) is a rare neurological disorder resulting from damage to or near the parotid glands responsible for making saliva, and from damage to the facial nerve often from surgery.[1][2]
The symptoms of Frey's syndrome are redness and sweating on the cheek area adjacent to the ear. They can appear when the affected person eats, sees, dreams, thinks about or talks about certain kinds of food which produce strong salivation.[citation needed] Observing sweating in the region after eating a lemon wedge may be diagnostic.[2]
Contents
- 1 Signs and symptoms
- 2 Causes
- 3 Treatments
- 4 Epidemiology
- 5 History
- 6 References
- 7 External links
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Signs and symptoms [edit]
Signs and symptoms include erythema (redness/flushing) and sweating in the cutaneous distribution of the auriculotemporal nerve, usually in response to gustatory stimuli. There is sometimes pain in the same area, often of a burning nature. Between attacks of pain there is sometimes numbness or other alterred sensations (anesthesia or paresthesia). This is sometimes termed "gustatory neuralgia".
Causes [edit]
Frey's syndrome often results as a side effect of surgeries of or near the parotid gland or due to injury to the auricotemporal nerve, which passes through the parotid gland in the early part of its course. The Auriculotemporal branch of the Trigeminal nerve carries sympathetic fibers to the sweat glands of the scalp and parasympathetic fibers to the parotid gland. As a result of severance and inappropriate regeneration, the parasympathetic nerve fibers may switch course, resulting in "gustatory Sweating" or sweating in the anticipation of eating, instead of the normal salivatory response.[2] It is often seen with patients who have undergone endoscopic thoracic sympathectomy, a surgical procedure wherein part of the sympathetic trunk is cut or clamped to treat sweating of the hands or blushing. The subsequent regeneration or nerve sprouting leads to abnormal sweating and salivating. It can also include discharge from the nose when smelling certain food.
Rarely, Frey's syndrome can result from causes other than surgery, including accidental trauma,local infecitons, sympathetic dysfunction and pathologic lesions within the parotid gland.
Treatments [edit]
There is no effective treatment, but various options are described:
- Injection of Botulinum Toxin A[3]
- Surgical transection of the nerve fibers (only a temporary treatment)[citation needed]
- Application of an ointment containing an anticholinergic drug such as scopolamine[citation needed]
Epidemiology [edit]
The condition is rare.
History [edit]
It is named after Łucja Frey-Gottesman.[4][5]
References [edit]
- ^ a b Office of Rare Diseases Research (2011). "Frey's syndrome". National Institutes of Health. Retrieved 17 December 2012.
- ^ a b c "Frey's Syndrome". New England Journal of Medicine. 2006. Retrieved 17 December 2012.
- ^ "Onabotulinumtoxina (Injection Route, Intradermal Route, Intramuscular Route)". Mayo Clinic. 2011. Retrieved 18 December 2012.
- ^ synd/390 at Who Named It?
- ^ L. Frey. Zespól nerwu uszno-skroniowego. 1923.
External links [edit]
Oral pathology: Stomatognathic disease (K06, K11–K14, 523, 527–529)
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Vestibule of mouth |
Lips
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Cheilitis (Angular, Actinic) · Herpes labialis · Plasma cell cheilitis · Cheilitis granulomatosa · Chapped lips
Cheilitis exfoliativa · Cheilitis glandularis · Allergic contact cheilitis
Drug-induced ulcer of the lip · Epidermization of the lip
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Buccal mucosa
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Morsicatio buccarum
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Oral cavity proper |
Hard, soft,
and periapical tissues
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gingival disease: Gingivitis (Desquamative gingivitis), Pericoronitis, Necrotizing ulcerative gingivitis, Noma, Epulis · Acute necrotizing ulcerative gingivitis
Periodontitis · Osteoradionecrosis · Periapical periodontitis
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Salivary glands |
Sialadenitis (Parotitis) · Benign lymphoepithelial lesion · Necrotizing sialometaplasia · Ranula · Sialolithiasis · Mucous cyst of the oral mucosa · Sjögren's syndrome · Pleomorphic adenoma
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Tongue |
Glossitis (Geographic tongue) · Fissured tongue · burning mouth syndrome · Black hairy tongue · Strawberry tongue · Caviar tongue · Median rhomboid glossitis · Osseous choristoma of the tongue · Smooth tongue
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General |
Stomatitis: Aphthous stomatitis · Gingivostomatitis
Velopharyngeal inadequacy
oral mucosa: Erythroplakia · Leukoplakia · Hairy leukoplakia · Leukoedema · Ulcer · White sponge nevus
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To be grouped
from derm |
Acquired dyskeratotic leukoplakia · Angina bullosa haemorrhagica · Behçet syndrome · Cutaneous sinus of dental origin · Cyclic neutropenia · Epulis fissuratum · Eruptive lingual papillitis · Melanocytic oral lesion · Melkersson–Rosenthal syndrome · Mucosal lichen planus · Oral Crohn's disease · Oral florid papillomatosis · Oral melanosis · Plasmoacanthoma · Proliferative verrucous leukoplakia · Pyogenic granuloma · Pyostomatitis vegetans · Recurrent intraoral herpes simplex infection · Stomatitis nicotina · Trumpeter's wart · Vestibular papillomatosis
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noco/cofa (c)/cogi/tumr, sysi
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UpToDate Contents
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English Journal
- Analysis of the retroauricular transmeatal approach: a novel transfacial access to the mandibular skeleton.
- Arcuri F, Brucoli M, Benech A.SourceDepartment of Maxillo-Facial Surgery, Azienda Ospedaliera Maggiore della Carità University of Piemonte Orientale "Amedeo Avogadro", Novara, Italy.
- The British journal of oral & maxillofacial surgery.Br J Oral Maxillofac Surg.2011 Sep 15. [Epub ahead of print]
- In 2005 experimental work was published about the successful surgical management of fractures of the condylar head through a retroauricular approach. There were two reports in German, and later publications have not mentioned this route to open reduction and internal fixation of such fractures. The
- PMID 21924804
Japanese Journal
- 臨床 下顎骨関節突起骨折後に発症したFrey症候群
- 藤井 達也,合田 正和,松田 和徳 [他],宮崎 かつし,峯田 一秀,中川 宏治,武田 憲昭
- 耳鼻咽喉科臨床 106(1), 13-16, 2013
- … Frey's syndrome is a complication associated with parotid tumor operation. … We report herein on a 70-year-old man who developed Frey's syndrome after fracturing his mandibular condyle. … Although he underwent manipulative reduction, but not an operation, it is suggested that the dislocated condyle injured the auriculotemporal nerve, resulting in the development of Frey's syndrome. …
- NAID 130003373991
- 下顎骨関節突起骨折術後に発症した Frey 症候群の1例
- 坂下 英明,宮田 勝,宮本 日出,宮地 優子
- 日本口腔診断学会雑誌 = Japanese journal of oral diagnosis/oral medicine 9(1), 171-173, 1996-03-20
- NAID 10019009826
- A variation of the auriculotemporal syndrome
Related Links
- Frey's syndrome (also known as Baillarger's syndrome, Dupuy's syndrome, Auriculotemporal syndrome or Frey-Baillarger syndrome) is a food related syndrome which can be congenital or acquired specially after parotid surgery and can ...
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- 英
- Frey syndrome, Frey's syndrome
- 同
- フレー症候群、味覚性発汗症候群 gustatory sweating syndrome、耳介側頭神経症候群 auriculotemporal nerve syndrome、耳介側頭症候群 auriculotemporal syndrome
- 関
- 術後Frey症候群
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