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1. 腹膜透析患者における腹腔および胸腔の裂孔の診断法 modalities for the diagnosis of abdominal and thoracic cavity defects in peritoneal dialysis patients
2. 膵神経内分泌腫瘍（膵島細胞腫瘍）の分類、疫学、臨床症状、局在、および病期分類 classification epidemiology clinical presentation localization and staging of pancreatic neuroendocrine tumors islet cell tumors
3. シェーグレン症候群の診断および分類 diagnosis and classification of sjogrens syndrome
4. 転移性胃腸膵管系神経内分泌腫瘍：症状、予後、画像検査、および生化学的モニタリング metastatic gastroenteropancreatic neuroendocrine tumors presentation prognosis imaging and biochemical monitoring
5. カルチノイド症候群および腫瘍局在の診断 diagnosis of the carcinoid syndrome and tumor localization

English Journal

Devised a New Preoperative Simulation Using (99m)Tc-GSA SPECT Quantitative Method for Liver Resection.

Orita Y1, Onodera A, Natsume T.
Nihon Hōshasen Gijutsu Gakkai zasshi.Nihon Hoshasen Gijutsu Gakkai Zasshi.2016;72(1):50-7. doi: 10.6009/jjrt.2016_JSRT_72.1.50.
PURPOSE: We developed a new imaging method to assess liver function by analyzing the amount of liver asialo single photon emission computed tomography (SPECT) using technetium-99m diethylenetriamine pentaacetic acid galactosyl human serum albumin ((99m)Tc-GSA) injection. A preoperative simulation us
PMID 26796933

Assessment of safety in hepatic resection for hepatocellular carcinoma focusing on indirect hyperbilirubinemia.

Masuda T1, Beppu T, Nakagawa S, Okabe H, Chikamoto A, Miyata T, Mima K, Otao R, Hayashi H, Doi K, Ishiko T, Takamori H, Baba H.
Journal of hepato-biliary-pancreatic sciences.J Hepatobiliary Pancreat Sci.2013 Mar;20(3):370-4. doi: 10.1007/s00534-012-0540-8.
BACKGROUND/PURPOSE: The indications for hepatic resection for hepatocellular carcinoma (HCC) patients with total bilirubin (T-Bil) equal to or higher than 1.2 mg/dl remain controversial. The aim of this study was to investigate the safety of hepatic resection for HCC patients who showed high T-Bil (
PMID 22892594

In patients treated with peritoneal dialysis, icodextrin improves erythropoietin-resistant anemia through blockade of asialo receptors on hepatocytes.

Adachi Y1, Nakagawa Y, Nishio A.
Advances in peritoneal dialysis. Conference on Peritoneal Dialysis.Adv Perit Dial.2006;22:41-4.
Although erythropoietin (EPO) derivatives improve anemic status in most end-stage renal disease patients, some EPO-resistant patients remain. Asialo-type EPO is as effective as is native EPO in vitro, but in vivo, it is quickly trapped by the hepatic asialo receptors. Alkaline phosphatase (ALP) also
PMID 16983937

Area between the hepatic and heart curves of ⁹⁹mTc-galactosyl-human serum albumin scintigraphy represents liver function and disease progression for preoperative evaluation in hepatocellular carcinoma patients

アシアロ糖たん白（ASGP）受容体は，哺乳類の肝細胞にのみ存在し，ASGPのガラクトース残基を認識してASGPを肝細胞内に取り込む3)。アルブミンにガラクトースを結合させた本剤のような合成糖たん白も，天然のASGPと生理的に等価にASGP受容体に取り込まれる4)。ASGP受容体量は肝疾患の病態によって減少することが知られており5)，放射性核種で標識した合成糖たん白を投与し体内での肝集積の様相を評価することによって肝機能を診断することができる1,2,6)。
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