同: 前神経孔

WordNet

of or near the head end or toward the front plane of a body
earlier in time (同)prior

PrepTutorEJDIC

(場所などが)前の,前部の;(…より)前に位置する《+『to』+『名』》 / (時・事件などが)以前の,先の;(…より)前の《+『to』+『名』》

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/08/14 17:30:49」(JST)

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The rostral neuropore or anterior neuropore is a region corresponding to the opening of the embryonic neural tube in the anterior portion of the developing prosencephalon. The central nervous system develops from the neural tube, which initially starts as a plate of cells in the ectoderm and this is called the neural plate, the neural plate then undergoes folding and starts closing from the center of the developing fetus, this leads to two open ends, one situated cranially/rostrally and the other caudally. Bending of the neural plate begins on day 22,^[1] and the cranial neuropore closes on day 24.^[2] giving rise to the lamina terminalis of the brain.

Failure to close

Failure of closure of the anterior neuropore during embryogenesis will lead to anencephaly, the failure of the brain and skull to develop.

Failure of closure of the posterior neuropore (caudal neuropore) during embryogenesis will lead to spina bifida.

References

^ Human Embryology, 4th edition, ISBN 978-0443-06811-9 PA
^ O'Rahilly R, Müller F. Bidirectional closure of the rostral neuropore in the human embryo].Am J Anat. 1989 Apr;184(4):259-68 PMID 2756902

UpToDate Contents

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1. 女性の骨盤臓器脱：後膣壁脱の外科的修復 pelvic organ prolapse in women surgical repair of anterior vaginal wall prolapse
2. 左脚前枝ブロック left anterior fascicular block
3. 強膜炎の臨床症症状および診断 clinical manifestations and diagnosis of scleritis
4. 非動脈炎性前部虚血性視神経症：臨床的特徴および診断 nonarteritic anterior ischemic optic neuropathy clinical features and diagnosis
5. 非動脈炎性前部虚血性視神経症：疫学、発症機序、および病因 nonarteritic anterior ischemic optic neuropathy epidemiology pathogenesis and etiologies

English Journal

Suprasellar dermoid cyst associated with colloid cyst of the third ventricle: Disordered embryogenesis or a mere coincidence?

Kurwale N, Kumar R, Sharma MC, Sharma BS.Author information Department of Neurosurgery and Gamma Knife, All India Institute of Medical Sciences, New Delhi, India.AbstractIntracranial dermoid cyst and colloid cysts of the third ventricle are rare benign congenital lesions of early adulthood. Both lesions are thought to be congenital in origin however association is rare. Only one case of this association has been reported. We report a 22-year-old male with suprasellar dermoid cyst and colloid cyst of the third ventricle presenting simultaneously. Embryogenesis of this association has been discussed.
Journal of neurosciences in rural practice.J Neurosci Rural Pract.2013 Jul;4(3):345-7. doi: 10.4103/0976-3147.118803.
Intracranial dermoid cyst and colloid cysts of the third ventricle are rare benign congenital lesions of early adulthood. Both lesions are thought to be congenital in origin however association is rare. Only one case of this association has been reported. We report a 22-year-old male with suprasella
PMID 24250183

Development of the hypothalamus and pituitary in platypus (Ornithorhynchus anatinus) and short-beaked echidna (Tachyglossus aculeatus).

Ashwell KW.Author information Department of Anatomy, School of Medical Sciences, The University of New South Wales, Sydney, NSW, Australia. k.ashwell@unsw.edu.auAbstractThe living monotremes (platypus and echidnas) are distinguished by the development of their young in a leathery-shelled egg, a low and variable body temperature and a primitive teat-less mammary gland. Their young are hatched in an immature state and must deal with the external environment, with all its challenges of hypothermia and stress, as well as sourcing nutrients from the maternal mammary gland. The Hill and Hubrecht embryological collections have been used to follow the structural development of the monotreme hypothalamus and its connections with the pituitary gland both in the period leading up to hatching and during the lactational phase of development, and to relate this structural maturation to behavioural development. In the incubation phase, development of the hypothalamus proceeds from closure of the anterior neuropore to formation of the lateral hypothalamic zone and putative medial forebrain bundle. Some medial zone hypothalamic nuclei are emerging at the time of hatching, but these are poorly differentiated and periventricular zone nuclei do not appear until the first week of post-hatching life. Differentiation of the pituitary is also incomplete at hatching, epithelial cords do not develop in the pars anterior until the first week, and the hypothalamo-neurohypophyseal tract does not appear until the second week of post-hatching life. In many respects, the structure of the hypothalamus and pituitary of the newly hatched monotreme is similar to that seen in newborn marsupials, suggesting that both groups rely solely on lateral hypothalamic zone nuclei for whatever homeostatic mechanisms they are capable of at birth/hatching.
Journal of anatomy.J Anat.2012 Jul;221(1):9-20. doi: 10.1111/j.1469-7580.2012.01508.x. Epub 2012 Apr 18.
The living monotremes (platypus and echidnas) are distinguished by the development of their young in a leathery-shelled egg, a low and variable body temperature and a primitive teat-less mammary gland. Their young are hatched in an immature state and must deal with the external environment, with all
PMID 22512474

Endonasal endoscopic approach for removal of intranasal nasal glial heterotopias.

Bonne NX, Zago S, Hosana G, Vinchon M, Van den Abbeele T, Fayoux P.Author information Department of Pediatric Otolaryngology, Jeanne de Flandre Children Hospital, University Hospital of Lille, Lille, France.AbstractBACKGROUND: Nasal Glial Heterotopias also called Nasal Gliomas (NG) are rare congenital tumours of the midline frontonasal space arising from a normal neurectodermal tissue entrapped during the closure of the anterior neuropore. Historically, such tumours were approached using a frontal craniotomy. The study aims to evaluate a fully endonasal endoscopic approach for intranasal NG removal.
Rhinology.Rhinology.2012 Jun;50(2):211-7. doi: 10.4193/Rhino11.108.
BACKGROUND: Nasal Glial Heterotopias also called Nasal Gliomas (NG) are rare congenital tumours of the midline frontonasal space arising from a normal neurectodermal tissue entrapped during the closure of the anterior neuropore. Historically, such tumours were approached using a frontal craniotomy.
PMID 22616084

Japanese Journal

Concanavalin-A-induced Open Neural Tube Defects in Chick Embryos

稲垣隆介,WANG Kyu-Chang,HIGBEE Russell G.,MCLONE David G.,KNEPPER Paul A.
Neurologia medico-chirurgica 36(10), 691-697, 1996-10-15
… Hamburger and Hamiltonの分類で、anterior neuroporeの閉鎖する以前のステージ10-11の時期に処理をしたところ、cranalもしくは広い範囲の二分脊椎を有す胎児が得らた。 … その一方で、posterior neuroporeの閉鎖する時期に相当するステージ12-14に処理をしたものでは、胸腰椎部に二分脊椎を有する個体が得られた。 …
NAID 110002278842

The Morphogenesis of Hindbrain Crowding Associated with Lumbosacral Myeloschisis

HUNG Chi-Fu,NAKAGATA Naomi,SATO Kiyoshi
Neurologia medico-chirurgica 29(11), 981-988, 1989-11-15
… At gestational days 12 and 13, the volume of the caudal end of the neural tube from the anterior border of the hindlimb bud to the most caudal portion of the fetus was significantly greater in ETU-exposed than in control rat embryos. … Experimental rat embryos also exhibited disturbance in closure of the posterior neuropore, with extrusion of neural tissue through the opening. …
NAID 110002277977

ウサギに対するサリドマイドの催奇形性 : (4)JW-NIBSウサギの前神経孔閉鎖不全の走査電顕的観察

見上学,松原孝雄,山中宏志,鈴木芳和
先天異常 : 日本先天異常学会会報 : official journal of Congeital Anomalies Research Association of Japan 23(3), 309-310, 1983-09-30
NAID 110002727908