anetholtrithion

アネトールトリチオン

anethole trithione

English Journal

  • Anethole dithiolethione lowers the homocysteine and raises the glutathione levels in solid tissues and plasma of rats: a novel non-vitamin homocysteine-lowering agent.
  • Giustarini D1, Fanti P2, Sparatore A3, Matteucci E4, Rossi R5.
  • Biochemical pharmacology.Biochem Pharmacol.2014 May 15;89(2):246-54. doi: 10.1016/j.bcp.2014.03.005. Epub 2014 Mar 14.
  • High homocysteine (Hcys) levels are suspected to contribute to the pathogenesis of cardiovascular disease and of other chronic conditions. Failure of B vitamins to reduce the incidence of cardiovascular events while lowering the Hcys levels, has prompted the search for alternative treatments. We tes
  • PMID 24637238
  • An examination of the potential effect of lipids on the first-pass metabolism of the lipophilic drug anethol trithione.
  • Yu HZ1, Han SF, Li P, Zhu CL, Zhang XX, Gan L, Gan Y.
  • Journal of pharmaceutical sciences.J Pharm Sci.2011 Nov;100(11):5048-58. doi: 10.1002/jps.22702. Epub 2011 Jul 15.
  • In this study, an examination of the potential effect of lipids on the first-pass metabolism of anethol trithione (ATT) was investigated. ATT is metabolized rapidly and extensively in liver into 4-hydroxy-anethole trithione (ATX), which was confirmed using the rat intestinal perfusion with the mesen
  • PMID 21766311
  • An HPLC-MS/MS method for the quantitative determination of 4-hydroxy-anethole trithione in human plasma and its application to a pharmacokinetic study.
  • He J1, Qin T, Wen J, Qin F, Li F.
  • Journal of pharmaceutical and biomedical analysis.J Pharm Biomed Anal.2011 Feb 20;54(3):551-6. doi: 10.1016/j.jpba.2010.09.037. Epub 2010 Oct 8.
  • A selective, rapid and sensitive method for the quantitation of 4-hydroxy-anethole trithione (ATX) in human plasma based on high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) was developed and validated. Paracetamol was used as the internal standard (I.S.). After liquid-liq
  • PMID 20980118

Japanese Journal

  • シェーグレン症候群に伴う口腔乾燥症患者に対するニザチジンの唾液分泌促進効果
  • 日本口腔内科学会雑誌 = Journal of Japanese Society of Oral Medicine 18(2), 44-51, 2012-12
  • NAID 40019816704
  • シェーグレン症候群に伴う口腔乾燥症患者に対するニザチジンの唾液分泌促進効果
  • 難水溶性製剤の溶出試験に界面活性剤として使用されるラウリル硫酸ナトリウムの品質に関する研究(第1報)
  • 医薬品医療機器レギュラトリーサイエンス 42(7), 626-632, 2011
  • NAID 40018949474

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