アンドロスタン
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/02/28 09:56:53」(JST)
[Wiki en表示]
Androstane |
|
IUPAC name
(8S,9S,10S,13S,14S)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene
|
|
Identifiers |
CAS number |
24887-75-0 Y,
438-22-2 (5α)
438-23-3 (5β) |
PubChem |
94144 |
ChemSpider |
5256872 Y |
ChEBI |
CHEBI:35509 Y |
Jmol-3D images |
Image 1
Image 2 |
-
C[C@@]12[C@](CCC2)([H])[C@]3([H])CCC4([H])CCCC[C@]4(C)[C@@]3([H])CC1
C3C1CCCC[C@@]1([C@H]2CC[C@]4([C@H]([C@@H]2C3)CCC4)C)C
|
-
InChI=1S/C19H32/c1-18-11-5-7-16(18)15-9-8-14-6-3-4-12-19(14,2)17(15)10-13-18/h14-17H,3-13H2,1-2H3/t14?,15-,16-,17-,18-,19-/m0/s1 Y
Key: QZLYKIGBANMMBK-FZFXZXLVSA-N Y
InChI=1/C19H32/c1-18-11-5-7-16(18)15-9-8-14-6-3-4-12-19(14,2)17(15)10-13-18/h14-17H,3-13H2,1-2H3/t14?,15-,16-,17-,18-,19-/m0/s1
Key: QZLYKIGBANMMBK-FZFXZXLVBX
|
Properties |
Molecular formula |
C19H32 |
Molar mass |
260.46 g mol−1 |
Y (verify) (what is: Y/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
Infobox references |
Androstane is a steroid. Androstane can exist as either of two isomers, known as 5α-androstane and 5β-androstane.
See also
Steroid classification
|
|
C17 |
|
|
C18 |
|
|
C19 |
|
|
C21 |
|
|
C23 |
|
|
C24 |
|
|
C27 |
|
|
Functional group |
- 17-Ketosteroid
- Hydroxysteroid
- Halogenated steroid
|
|
Elements removed |
|
|
Anabolic steroids (A14)
|
|
Androstane (carbon 19 present) |
- Adrenosterone
- Androisoxazole
- Bolasterone (Myagen)
- Bolazine
- Boldione
- Boldenone undecylenate (Equipoise)
- 4-Chlordehydromethyltestosterone (Turinabol)
- 4-Hydroxytestosterone
- Calusterone
- Clostebol
- Danazol
- Desoxymethyltestosterone (Madol)
- DHT
- Drostanolone (Masteron)
- Enestebol
- Epitiostanol
- Fluoxymesterone (Halotestin)
- Formebolone
- Furazabol (Miotolan)
- Hydroxystenozole
- Mebolazine
- Mesabolone
- Mestanolone
- Mesterolone (Proviron)
- Methandriol
- Methandrostenolone (Dianabol)
- Metenolone
- Methenolone enanthate (Primobolan)
- Methasterone (Superdrol)
- Methyltestosterone
- Oxandrolone (Anavar)
- Oxymetholone (Anadrol)
- Oxymesterone
- Prostanozol
- Quinbolone (Anabolicum Vister)
- Roxibolone
- Silandrone
- Stanozolol (Strombafort
- Winstrol)
- Stenbolone
- Testosterone`s (Sustamed
- Sustanon)
- 1-Testosterone
- Thiomesterone
- Trestolone
|
|
Estrene (carbon 19 absent) |
- Bolenol
- Ethyldienolone
- Ethylestrenol
- Mibolerone (Cheque Drops)
- Methylnortestosterone
- Metribolone (R1881)
- Nandrolone (Deca Durabolin)
- Norboletone (Genabol)
- Norclostebol
- Norethandrolone
- Normethandrone
- Oxabolone cipionate
- Propetandrol
- Tetrahydrogestrinone (The Clear)
- Trenbolone (Fina)
|
|
Prohormones |
- 1-Androstenediol
- 1,4-Androstadienedione
- 4-Androstenediol
- 4-Androstenedione
- 19-Norandrostenediol
- 19-Norandrostenedione
- DHEA
|
|
|
anat (t, g, p)/phys/devp/enzy
|
noco/cong/tumr, sysi/epon
|
proc, drug (A2A/2B/3/4/5/6/7/14/16), blte
|
|
|
|
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
English Journal
- Wild-type and specific mutant androgen receptor mediates transcription via 17β-estradiol in sex hormone-sensitive cancer cells.
- Susa T1, Ikaga R, Kajitani T, Iizuka M, Okinaga H, Tamamori-Adachi M, Okazaki T.
- Journal of cellular physiology.J Cell Physiol.2015 Jul;230(7):1594-606. doi: 10.1002/jcp.24906.
- We previously encountered regulatory processes wherein dihydrotestosterone (DHT) exerted its inhibitory effect on parathyroid hormone-related protein (PTHrP) gene repression through the estrogen receptor (ER)α, but not the androgen receptor (AR), in breast cancer MCF-7 cells. Here, we investigated
- PMID 25536295
- Pronamide: Weight of evidence for potential estrogen, androgen or thyroid effects.
- Marty MS1, Papineni S2, Coady KK3, Rasoulpour RJ2, Pottenger LH3, Eisenbrandt DL2.
- Regulatory toxicology and pharmacology : RTP.Regul Toxicol Pharmacol.2015 Jul;72(2):405-22. doi: 10.1016/j.yrtph.2015.03.016. Epub 2015 Apr 4.
- Based on the exposure potential to humans and environment, pronamide was one of 52 chemicals on the first list evaluated under US EPA's Endocrine Disruptor Screening Program (EDSP). The purpose of EDSP is to screen chemicals for their potential to interact with estrogen-, androgen-, or thyroid-signa
- PMID 25846366
- Total Synthesis of Limonin.
- Yamashita S1, Naruko A2, Nakazawa Y2, Zhao L2, Hayashi Y2, Hirama M2,3.
- Angewandte Chemie (International ed. in English).Angew Chem Int Ed Engl.2015 Jun 3. doi: 10.1002/anie.201503794. [Epub ahead of print]
- Limonoids are highly oxygenated C13α-triterpenes and common secondary metabolites. Several hundred congeners have been isolated to date. The first total synthesis of (±)-limonin, the flagship congener of the limonoids, is now reported and features 1) a tandem radical cyclization generating the BCD
- PMID 26036432
Japanese Journal
- Roles of Xenobiotic Receptors in Vascular Pathophysiology
- Xiao Lei,Zhang Zihui,Luo Xiaoqin
- Circulation journal : official journal of the Japanese Circulation Society 78(7), 1520-1530, 2014-07
- NAID 40020098684
- P1-15-1 卵巣癌に対するConstitutive androstane receptorを介した抗癌剤効果増強,耐性克服に向けての新たな治療戦略(Group 15 卵巣腫瘍・基礎2,一般演題,公益社団法人日本産科婦人科学会第66回学術講演会)
- Human Hepatocarcinoma Functional Liver Cell-4 Cell Line Exhibits High Expression of Drug-Metabolizing Enzymes in Three-Dimensional Culture
- Kato Ryuji,Shigemoto Kota,Akiyama Hiromasa,Ieda Asaka,Ijiri Yoshio,Hayashi Tetsuya
- Biological and Pharmaceutical Bulletin 37(11), 1782-1787, 2014
- … The mRNA levels of HNF-4α, albumin, pregnane X receptor (PXR), constitutive androstane receptor (CAR), CYPs (1A2, 2E1, 2C8, 2C9, 2C19, 2D6, and 3A4) and UGTs (1A1, 1A6, 1A9, and 2B7) were determined using real-time reverse transcription (RT) PCR. …
- NAID 130004703899
Related Links
- Androstane. From Wikipedia, the free encyclopedia. Jump to: navigation, search. Androstane. IUPAC name. (8S,9S,10S,13S,14S)-10,13-dimethyl-2,3,4,5,6,7,8,9, 11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene. Other names ...
- 2008年5月17日 ... アンドロスタンとその誘導体. Androstane アンドロスタン [IUPAC-IUB/CAS]: ※二重 結合を1つもつときは、Androstene アンドロステン。 Etiocholane エチオコラン: 5β- androstane [IUPAC-IUB] 5β-アンドロスタン: (5β)-androstane [CAS] ...
Related Pictures
★リンクテーブル★
[★]
- 英
- androstane
- 関
- ステロイドホルモン、ステロイド
[★]
アンドロスタン受容体、アンドロスタンレセプター
- 関
- CAR
[★]
ノルアンドロスタン