WordNet

first in order of importance; "the alpha male in the group of chimpanzees"; "the alpha star in a constellation is the brightest or main star"
the 1st letter of the Greek alphabet
the beginning of a series or sequence; "the Alpha and Omega, the first and the last, the beginning and the end"--Revelations
early testing stage of a software or hardware product; "alpha version"
any high mountain

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1. 筋萎縮性側索硬化症およびその他の運動ニューロン疾患の臨床的特徴 clinical features of amyotrophic lateral sclerosis and other forms of motor neuron disease
2. α-1アンチトリプシン欠乏の治療 treatment of alpha 1 antitrypsin deficiency
3. αサラセミアの病態生理 pathophysiology of alpha thalassemia
4. ステロイド5 -α-レダクターゼ2欠乏症 steroid 5 alpha reductase 2 deficiency
5. 原発性肝細胞癌の臨床的特徴および診断 clinical features and diagnosis of primary hepatocellular carcinoma

The anti-hyperalgesic and anti-inflammatory profiles of p-cymene: Evidence for the involvement of opioid system and cytokines.

de Santana MF1, Guimarães AG, Chaves DO, Silva JC, Bonjardim LR, Lucca Júnior Wd, Ferro JN, Barreto Ede O, Santos FE, Soares MB, Villarreal CF, Quintans Jde S, Quintans-Júnior LJ.
Pharmaceutical biology.Pharm Biol.2015 Nov;53(11):1583-90. doi: 10.3109/13880209.2014.993040. Epub 2015 Apr 9.
CONTEXT: Pain corresponds to the most frequent reason for visits to physicians, and its control by conventional drugs is accompanied by several side effects, making treatment difficult. For this reason, new chemical entities derived from natural products still hold great promise for the future of dr
PMID 25856703

The role of auxiliary subunits for the functional diversity of voltage-gated calcium channels.

Campiglio M1, Flucher BE1.
Journal of cellular physiology.J Cell Physiol.2015 Sep;230(9):2019-31. doi: 10.1002/jcp.24998.
Voltage-gated calcium channels (VGCCs) represent the sole mechanism to convert membrane depolarization into cellular functions like secretion, contraction, or gene regulation. VGCCs consist of a pore-forming α(1) subunit and several auxiliary channel subunits. These subunits come in multiple isofor
PMID 25820299

Insulin treatment restores glutamate (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptor function in the hippocampus of diabetic rats.

Viswaprakash N1, Vaithianathan T2,3, Viswaprakash A4, Judd R5, Parameshwaran K3,6, Suppiramaniam V3.
Journal of neuroscience research.J Neurosci Res.2015 Sep;93(9):1442-50. doi: 10.1002/jnr.23589. Epub 2015 Mar 24.
Type 1 diabetes is associated with cognitive dysfunction. Cognitive processing, particularly memory acquisition, depends on the regulated enhancement of expression and function of glutamate receptor subtypes in the hippocampus. Impairment of memory was been detected in rodent models of type 1 diabet
PMID 25807926

New recreational drug 1-phenyl-2-(1-pyrrolidinyl)-1-pentanone (alpha-PVP) activates central nervous system via dopaminergic neuron

Kaizaki Asuka,Tanaka Sachiko,Numazawa Satoshi
The Journal of toxicological sciences : an official journal of the Japanese Society of Toxicology 39(1), 1-6, 2014-02
NAID 40019974806

田村進,西谷陽志,細川千絵,三好智満,澤井元,上村拓矢,八木康史,水野(松本) 由子,陳延偉
電子情報通信学会技術研究報告. MI, 医用画像 113(410), 225-230, 2014-01-19
… Neuron is a simple computational element with rough function, e.g. it cannot receive spikes between refractory period of after it fires. … However, as a neuron network they can work intellectually. … We detected pseudo random sequences including M-sequence family in spike trains of cultured neuron network significantly more than by chance. …
NAID 110009821268

Nardilysin prevents amyloid plaque formation by enhancing α-secretase activity in an Alzheimer's disease mouse model.

Ohno Mikiko,Hiraoka Yoshinori,Lichtenthaler Stefan F,Nishi Kiyoto,Saijo Sayaka,Matsuoka Tatsuhiko,Tomimoto Hidekazu,Araki Wataru,Takahashi Ryosuke,Kita Toru,Kimura Takeshi,Nishi Eiichiro
Neurobiology of aging 35(1), 213-222, 2014-01
… Alpha-cleavage of APP by α-secretase has a potential to preclude the generation of Aβ because it occurs within the Aβ domain. … Here we demonstrate that the neuron-specific overexpression of NRDc prevents Aβ deposition in the AD mouse model. …
NAID 120005347112