- 関
- apoE receptor、apolipoprotein E receptor、LDL-receptor related protein 1
WordNet
- first in order of importance; "the alpha male in the group of chimpanzees"; "the alpha star in a constellation is the brightest or main star"
- the 1st letter of the Greek alphabet
- the beginning of a series or sequence; "the Alpha and Omega, the first and the last, the beginning and the end"--Revelations
- early testing stage of a software or hardware product; "alpha version"
- a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response
- any high mountain
PrepTutorEJDIC
- アルファ(ギリシア語アルファベットの第1字A,α;英語のA,aに相当) / アルファ星(星座の主星)
- =sense organ / 受信装置
- 高山,高峰
UpToDate Contents
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English Journal
- Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance.
- Zhao Z1, Sagare AP1, Ma Q1, Halliday MR1, Kong P1, Kisler K1, Winkler EA2, Ramanathan A1, Kanekiyo T3, Bu G3, Owens NC1, Rege SV1, Si G1, Ahuja A1, Zhu D4, Miller CA5, Schneider JA6, Maeda M7, Maeda T7, Sugawara T8, Ichida JK8, Zlokovic BV1.
- Nature neuroscience.Nat Neurosci.2015 May 25. doi: 10.1038/nn.4025. [Epub ahead of print]
- PICALM is a highly validated genetic risk factor for Alzheimer's disease (AD). We found that reduced expression of PICALM in AD and murine brain endothelium correlated with amyloid-β (Aβ) pathology and cognitive impairment. Moreover, Picalm deficiency diminished Aβ clearance across the murine blo
- PMID 26005850
- ApoE4 and Aβ Oligomers Reduce BDNF Expression via HDAC Nuclear Translocation.
- Sen A1, Nelson TJ2, Alkon DL2.
- The Journal of neuroscience : the official journal of the Society for Neuroscience.J Neurosci.2015 May 13;35(19):7538-51. doi: 10.1523/JNEUROSCI.0260-15.2015.
- Apolipoprotein E4 (ApoE4) is a major genetic risk factor for several neurodegenerative disorders, including Alzheimer's disease (AD). Epigenetic dysregulation, including aberrations in histone acetylation, is also associated with AD. We show here for the first time that ApoE4 increases nuclear trans
- PMID 25972179
- Antisense RNA Controls LRP1 Sense Transcript Expression through Interaction with a Chromatin-Associated Protein, HMGB2.
- Yamanaka Y1, Faghihi MA1, Magistri M1, Alvarez-Garcia O2, Lotz M2, Wahlestedt C3.
- Cell reports.Cell Rep.2015 May 12;11(6):967-76. doi: 10.1016/j.celrep.2015.04.011. Epub 2015 Apr 30.
- Long non-coding RNAs (lncRNAs), including natural antisense transcripts (NATs), are expressed more extensively than previously anticipated and have widespread roles in regulating gene expression. Nevertheless, the molecular mechanisms of action of the majority of NATs remain largely unknown. Here, w
- PMID 25937287
Japanese Journal
- Genetic and functional characteristics of the human in vivo LRP1/A2MR receptor suggested as a risk marker for Alzheimer's disease and other complex (degenerative) diseases
- Neuroscience research : the official journal of the Japan Neuroscience Society 50(1), 85-101, 2004-09-01
- NAID 10023900957
- Genetic association of argyrophilic grain disease with polymorphisms in alpha-2 macroglobulin and low-density lipoprotein receptor-related protein genes
- An Experimental Renal Disease Induced by the Genetic Immunization of Alpha-2 Macroglobulin Receptor-Associated Protein cDNA
★リンクテーブル★
[★]
- 関
- alpha 2-macroglobulin receptor、apolipoprotein E receptor、LDL-receptor related protein 1
[★]
- 関
- alpha 2-macroglobulin receptor、apoE receptor、LDL-receptor related protein 1
[★]
- 英
- alpha 2-macroglobulin receptor
- 関
- ア・リ・蛋白E受容体、LDL受容体関連タンパク質1、α2-マクログロブリン受容体、α2マクログロブリンレセプター、α2-マクログロブリンレセプター
[★]
- 英
- alpha 2-macroglobulin receptor
- 関
- α2マクログロブリン受容体、α2マクログロブリンレセプター、α2-マクログロブリンレセプター
[★]
- 英
- alpha 2-macroglobulin receptor
- 関
- α2マクログロブリン受容体、α2-マクログロブリン受容体、α2-マクログロブリンレセプター
[★]
α、アルファ
- 関
- alfa