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1. アルコール使用障害への治療アプローチapproach to treating alcohol use disorder [show details]
…days of abstinence . The psychiatric diagnoses, alcohol abuse and alcohol dependence, in DSM-IV-TR were replaced by one diagnosis, alcohol use disorder, in DSM-5 . Although the crosswalk between DSM-IV …
2. アルコールの慢性神経学的合併症の概要overview of the chronic neurologic complications of alcohol [show details]
…abnormalities of alcoholics . There is evidence for regional vulnerability in the brains of alcohol abusers . Neuronal density in the superior frontal cortex was reduced by 22 percent in alcohol abusers compared …
3. アルコール性心筋症alcoholic cardiomyopathy [show details]
… threshold alcohol consumption used to identify alcoholic cardiomyopathy . The prevalence of alcoholic cardiomyopathy appears to be similar among alcoholic men and women, with women developing the condition …
4. アルコール使用障害の心理社会的治療psychosocial treatment of alcohol use disorder [show details]
… are reviewed in greater detail separately. Alcoholics Anonymous (AA), the best known program, is a voluntary program for people with an alcohol use disorder, based on fellowship and a belief in a spiritual …
5. アルコール性脂肪性肝炎およびアルコール性肝硬変の臨床症状および診断clinical manifestations and diagnosis of alcoholic fatty liver disease and alcoholic cirrhosis [show details]
… with alcoholic liver disease may vary from normal to evidence of cirrhosis or hepatic decompensation Patients with alcoholic liver disease may also have extrahepatic manifestations of alcohol abuse such …

English Journal

Review of thiamine deficiency disorders: Wernicke encephalopathy and Korsakoff psychosis.

Chandrakumar A, Bhardwaj A, 't Jong GW.
Journal of basic and clinical physiology and pharmacology. 2018 Oct;30(2)153-162.
Wernicke encephalopathy (WE) and Korsakoff psychosis (KP), together termed Wernicke-Korsakoff syndrome (WKS), are distinct yet overlapping neuropsychiatric disorders associated with thiamine deficiency. Thiamine pyrophosphate, the biologically active form of thiamine, is essential for multiple bioch
PMID 30281514

Forgetting the new locations of one's keys: spatial-memory interference in Korsakoff's amnesia.

Postma A, Morel SG, Slot ME, Oudman E, Kessels RPC.
Experimental brain research. 2018 07;236(7)1861-1868.
The present study focused on interference in a group of patients with amnesia due to Korsakoff's syndrome (KS) within the domain of spatial memory. An object-location memory task was used in which participants first learned an array of objects on a computer screen, followed by a reconstruction of th
PMID 29680910

Substance use disorders and medical comorbidities among high-need, high-risk patients with diabetes.

Wu LT, Ghitza UE, Zhu H, Spratt S, Swartz M, Mannelli P.
Drug and alcohol dependence. 2018 05;186()86-93.
The majority of the U.S. healthcare resources are utilized by a small population characterized as high-risk, high-need persons with complex care needs (e.g., adults with multiple chronic conditions). Substance use disorders (SUDs) and mental health disorders (MHDs) are a driver of poor health and ad
PMID 29554592