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1. 薬物アレルギー患者へのアプローチan approach to the patient with drug allergy [show details]
… two common presentations of drug allergy. The main questions that arise in such situations include the following: Is the adverse event related to a drug?; If so, which drug is responsible?; Is the reaction …
2. 薬物熱drug fever [show details]
… caused by drugs, although reliable data on incidence are not available. Fever can be the sole manifestation of an adverse drug reaction in 3 to 5 percent of cases . The risk of developing drug fever increases …
3. 抗マラリア剤：概要antimalarial drugs an overview [show details]
…antimalarial drugs in Africa, especially those purchased outside the formal health care system . Antimalarial drugs are used for the treatment and prevention of malaria infection. Most antimalarial drugs target …
4. 抗結核薬：概要antituberculous drugs an overview [show details]
… in South Africa with drug-resistant TB treated with a regimen including both bedaquiline and delamanid, no additive or synergistic QT prolongation effects were observed . Drug-drug interactions have been …
5. リウマチ性疾患に用いる免疫抑制剤と従来型の（非生物学的製剤の）疾患修飾性抗リウマチ薬の概要overview of immunosuppressive and conventional non biologic disease modifying drugs in the rheumatic diseases [show details]
…an overview of the use of immunosuppressive drugs in various rheumatic diseases, including the conventional (non-biologic) disease-modifying antirheumatic drugs (DMARDs), sometimes referred to as traditional …

English Journal

Novel miRNA-based biomarker panel for detection β-agonists in goats.

Zhao L, Yang S, You X, He W, Xue J.
Food chemistry. 2019 Aug;288()15-21.
miRNA sequencing was applied in this work to screen miRNA biomarkers related to β-agonists from the test and control goat samples. A total of 10 selected miRNAs were proven by qRT-PCR to be able to separate treatment cell groups from the control. With previously reported differentially expressed ge
PMID 30902275

Dexmedetomidine: A multifaceted drug in perioperative medicine.

, F F, E E, E E, .
Journal of clinical anesthesia. 2019 08;55()1-2.
PMID 30562591

EP and EP receptor antagonists: Impact on cytokine production and β -adrenergic receptor desensitization in human airway smooth muscle.

Bradbury P, Rumzhum NN, Ammit AJ.
Journal of cellular physiology. 2019 Jul;234(7)11070-11077.
Prostaglandin E (PGE ) is a key prostanoid known to have both proinflammatory and anti-inflammatory impact in the context of chronic respiratory diseases. We hypothesize that these opposing effects may be the result of different prostanoid E (EP) receptor-mediated signaling pathways. In this study,
PMID 30536718

Japanese Journal

喘息患者における即時型皮内反応に及ぼす向交感神経薬剤の効果 : 代謝性反応との関連性について

近江徹広 [他],無江季次,田村弦,石原俊春,藤本覚,大場奈奈子,滝島任,陳慧珠
アレルギー 28(9), 674-682, 1979
喘息患者において即時型皮内反応に及ぼす交感神経系薬剤の効果を検討した.22例の家塵抗原による皮内反応陽性を示す患者に 10^<-7>M イソプロテレノールと抗原液との混合皮内注射を行うと, 10例で皮内反応は有意に縮小し, また 10^<-4>M プロプラノロールと抗原との混注では8例で有意に増大した.次に塩酸アドレナリン 0.08mg/min/kg/weight を10分 …
NAID 110002411618