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an inflammatory disease involving the sebaceous glands of the skin; characterized by papules or pustules or comedones
(of complexion) blemished by imperfections of the skin (同)pimpled, pimply, pustulate

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にきび(pimple)

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/08/26 17:41:18」(JST)

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Acne medicamentosa (commonly referred to as drug-induced acne) is acne that is caused or aggravated by medication.^[1] Because acne is generally a disorder of the pilosebaceous units caused by hormones, the medications that trigger acne medicamentosa most frequently are hormone analogues. It is also often caused by corticosteroids; in this case, it is referred to as steroid acne.

Although the masculinizing hormone testosterone is most often blamed, and although men with acne secondary to bodybuilding hormones are seen from time to time, the major hormonal medications that causes acne are the progestin analogues present in hormonal contraception. Other medications can produce acneiform eruptions (usually pimply bumps and pustules that look like acne).

Some conditions mimic acne medicamentosa. The most common mimic is folliculitis produced by an overgrowth of the Malassezia species, often secondary to oral or systemic corticosteroids, or secondary to broad-spectrum antibiotics such as the tetracycline family used in acne. This is often misinterpreted as 'tetracycline-resistant acne'.

References

^ Wolff, Klaus Dieter; et al. (2008). Fitzpatrick's Dermatology in General Medicine. McGraw-Hill Medical. ISBN 0-07-146690-8.

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1. 尋常性ざ瘡の治療 treatment of acne vulgaris
2. 尋常性ざ瘡の病因、臨床症状、および診断 pathogenesis clinical manifestations and diagnosis of acne vulgaris
3. にきびの傷のマネージメント management of acne scars
4. 尋常性ざ瘡を有する女性のホルモン療法 hormonal therapy for women with acne vulgaris
5. 女性における思春期後のざ瘡 postadolescent acne in women

English Journal

Acne and systemic disease.

Lolis MS1, Bowe WP, Shalita AR.
The Medical clinics of North America.Med Clin North Am.2009 Nov;93(6):1161-81. doi: 10.1016/j.mcna.2009.08.008.
Acne is the most common disease of the skin. It affects 85% of teenagers, 42.5% of men, and 50.9% of women between the ages of 20 and 30 years.96,97 The role of hormones, particularly as a trigger of sebum production and sebaceous growth and differentiation, is well known. Excess production of hormo
PMID 19932324

[The problem of vitamin B6/B12 acne. A contribution on acne medicamentosa (author's transl)].

Braun-Falco O, Lincke H.
MMW, Münchener medizinische Wochenschrift.MMW Munch Med Wochenschr.1976 Feb 6;118(6):155-60.
Deterioration of acne vulgaris or eruption of an acneiform exanthema could be established during treatment with vitamin B6 and/or vitamin B12 in 14 patients. Females were by far the more frequently affected. The appearance of skin symptoms, even outside the age groups typically affected by acne vulg
PMID 130553