出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/11/11 15:36:05」(JST)
Names | |
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IUPAC name
(4R)-4-[ [(2S)-2-[ [(2R)-2-[(2R,5S)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxypropanoyl]amino]propanoyl]amino]-5-amino-5-oxopentanoic acid
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Other names
Acetylmuramyl-Alanyl-Isoglutamine
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Identifiers | |
CAS Registry Number
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53678-77-6 Y |
ChemSpider | 9794910 Y |
InChI
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IUPHAR/BPS
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5024 |
Jmol-3D images | Image |
MeSH | Muramyl+dipeptide |
PubChem | 11620162 |
SMILES
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Properties | |
Chemical formula
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C19H32N4O11 |
Molar mass | 492.47758 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Y verify (what is: Y/N?) | |
Infobox references | |
Muramyl dipeptide is a peptidoglycan constituent of both Gram-positive and Gram-negative bacteria composed of N-acetylmuramic acid linked by its lactic acid moiety to the N-terminus of an L-alanine D-isoglutamine dipeptide.[1]
It can be recognized by the immune system as a pathogen-associated molecular pattern and activate the NALP3 inflammasome which in turn leads to cytokine activation, especially IL-1α and IL-1β. [2]
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リンク元 | 「muramyl dipeptide」「アセチルムラミルアラニルイソグルタミン」 |
関連記事 | 「alanyl」 |
アラニル、アラニンの
.