WordNet

a silvery ductile metallic element found primarily in bauxite (同)aluminium, Al, atomic number 13

PrepTutorEJDIC

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

[Comparative study of 3 drugs (aceglutamide aluminum, zinc acexamate, and magaldrate) in the long-term maintenance treatment (1 year) of peptic ulcer].

Varas Lorenzo MJ1, López Martínez A, Gordillo Bernal J, Mundet Surroca J.
Revista española de enfermedades digestivas : organo oficial de la Sociedad Española de Patología Digestiva.Rev Esp Enferm Dig.1991 Aug;80(2):91-4.
In a multicentre study, 146 peptic ulcer patients who had recently healed with H2 antagonists (38 gastric, 108 duodenal ulcers) received randomly for a year one of the following mucosal protecting antiulcer drugs: aceglutamide aluminium salt (AAL), zinc acexamate (ZAC) and magaldrate (MAG). Forty si
PMID 1790087

Seiki M1, Ueki S, Tanaka Y, Soeda M, Hori Y, Aita H, Yoneta T, Morita H, Tagashira E, Okabe S.
Nihon yakurigaku zasshi. Folia pharmacologica Japonica.Nihon Yakurigaku Zasshi.1990 May;95(5):257-69.
We investigated the anti-ulcer effects of zinc L-carnosine (Z-103) using several acute experimental models of gastric and duodenal lesions in rats. Effects of Z-103 on various gastric functions, e.g., antacid (in vitro), anti-pepsin (in vitro), gastric secretion, mucosal potential difference (PD) an
PMID 2113032

Tanaka H.
Arzneimittel-Forschung.Arzneimittelforschung.1986 Oct;36(10):1485-9.
Aceglutamide aluminium (AGA, KW-110, Glumal) at doses of 30-100 mg/kg p.o. prevented the formation of the gastric lesions induced by three noxious compounds, ethanol, HCl and acidified taurocholate, all dose-dependently. The preventive effect of AGA against taurocholate-induced lesions was more mark
PMID 3814209

清木雅雄,上木茂,田中芳明,添田美津雄,堀裕子,会田浩幸,米田智幸,森田仁,田頭栄治郎,岡部進
日本薬理学雑誌 95(5), 257-269, 1990
新規化合物Z-103の抗潰瘍剤としての有用性を明確にするため，各種実験胃損傷(ストレス胃損傷，塩酸aspirin胃損傷，histamine胃損傷及び塩酸ethanol胃損傷)，並びにmepirizole十二指腸潰瘍モデルに対する作用をラットを用いて検討した．対照薬物としてspizofuroneおよびcimetidineを使用した．Z-103は各モデルに対して用量依存的な抑制効果を示し，特に塩酸et …
NAID 130000759059

秦多恵子,喜多富太郎,浪松昭夫,伊藤栄次,小田泰雄
日本薬理学雑誌 79(4), 335-342, 1982
… 5mlずつ注入することにより，重症の潰瘍を惹起させ，潰瘍領域のmucosaおよびstroma中のhexosamine，sialic acid，uronic acidおよびhydroxyproline含量に対するaceglutamide aluminumの効果をL-glutamineの効果と比較検討した．aceglutamide aluminum(1000mg/kg×2/day)を手術の日から4日目までp.o.投与し5日目に薬効を評価した時，この薬物は潰瘍指数を18%，潰瘍部穿孔を66%抑制した．また潰瘍領域 …
NAID 130000759577