- 関
- acantholysis
WordNet
- a breakdown of a cell layer in the epidermis (as in pemphigus)
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/06/07 21:04:16」(JST)
[Wiki en表示]
Not to be confused with Acanthosis.
Acantholysis |
Foot-and-mouth disease - acantholysis in a sample of a skin vesicle: Necrosis of the stratum spinosum can be observed, and keratinocytes floating in the vesicular fluid (spongiosa).
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Classification and external resources |
ICD-10 |
L11.9 (ILDS L11.900) |
DiseasesDB |
31172 |
Acantholysis is the loss of intercellular connections, such as desmosomes, resulting in loss of cohesion between keratinocytes,[1] seen in diseases such as pemphigus vulgaris.[2] It is absent in bullous pemphigoid, making it useful for differential diagnosis.
This histological feature is also seen in herpes simplex infections (HSV 1 and 2).
See also
- Skin lesion
- Skin disease
- List of cutaneous conditions
References
- ^ Kumar, Vinay; Fausto, Nelso; Abbas, Abul (2004) Robbins & Cotran Pathologic Basis of Disease (7th ed.). Saunders. Page 1230. ISBN 0-7216-0187-1.
- ^ Medical Dictionary Entry
Clinical and histological nomenclature for skin lesions
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Macroscopic |
Primary lesions |
- flat
- elevated
- fluid
- Ulcer
- Erosion
- Telangiectasia
- Special initial lesions : Burrow
- Comedo
- Scutulum
- Target lesion
- Herald patch
- Wheal
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Secondary lesions |
- Scale
- Crust
- Lichenification
- Excoriation
- Induration
- Atrophy
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Microscopic |
- keratin: Hyperkeratosis
- Parakeratosis
- Dyskeratosis
- Hypergranulosis
- Acanthosis
- Papillomatosis
- Acantholysis
- Spongiosis
- Hydropic swelling
- Exocytosis
- Vacuolization
- Erosion
- Ulceration
- Lentiginous
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Index of skin
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Description |
- Anatomy
- Physiology
- Development
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Disease |
- Infections
- Vesiculobullous
- Dermatitis and eczema
- Papulosquamous
- Urticaria and erythema
- Radiation-related
- Pigmentation
- Mucinoses
- Keratosis, ulcer, atrophy, and necrobiosis
- Vasculitis
- Fat
- Neutrophilic and eosinophilic
- Congenital
- Neoplasms and cancer
- nevi and melanomas
- epidermis
- dermis
- Symptoms and signs
- Terminology
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Treatment |
- Procedures
- Drugs
- antibiotics
- disinfectants
- emollients and protectives
- itch
- psoriasis
- other
- Wound and ulcer
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- Vesiculobullous disease (L10–L14
- 694)
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Acantholysis
(epidermis) |
Pemphigus |
- Pemphigus vulgaris: Pemphigus vegetans
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- Pemphigus foliaceus: Pemphigus erythematosus
- Endemic pemphigus
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- IgA pemphigus
- Subcorneal pustular
- Intraepidermal neutrophilic
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Other |
- Transient acantholytic dermatosis
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Pemphigoid
(dermis) |
IgG: |
- Bullous pemphigoid
- Cicatricial pemphigoid
- Gestational pemphigoid
- Pemphigoid nodularis
- Epidermolysis bullosa acquisita
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IgA: |
- Linear IgA bullous dermatosis
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Other bullous |
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In diseases
classified elsewhere |
- Porphyria cutanea tarda
- Bullous lupus erythematosus
- PUVA-induced acrobullous dermatosis
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Index of skin
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|
Description |
- Anatomy
- Physiology
- Development
|
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Disease |
- Infections
- Vesiculobullous
- Dermatitis and eczema
- Papulosquamous
- Urticaria and erythema
- Radiation-related
- Pigmentation
- Mucinoses
- Keratosis, ulcer, atrophy, and necrobiosis
- Vasculitis
- Fat
- Neutrophilic and eosinophilic
- Congenital
- Neoplasms and cancer
- nevi and melanomas
- epidermis
- dermis
- Symptoms and signs
- Terminology
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Treatment |
- Procedures
- Drugs
- antibiotics
- disinfectants
- emollients and protectives
- itch
- psoriasis
- other
- Wound and ulcer
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UpToDate Contents
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English Journal
- Acrokeratosis verruciformis of Hopf exhibiting Darier disease-like cytological features.
- Harman M1, Durdu M2, İbiloğlu I3.
- Clinical and experimental dermatology.Clin Exp Dermatol.2016 Oct;41(7):761-3. doi: 10.1111/ced.12910.
- The relationship between acrokeratosis verruciformis (AVH; also known as Hopf disease) and Darier disease (DD) has been debated for several decades. There is still substantial controversy over the characterization and association of AVH with DD. Certain histopathological features overlapping with th
- PMID 27663152
- Papular Acantholytic Dyskeratosis of the Vulva in a Woman With Benign Familial Pemphigus.
- Baliu-Piqué C1, Iranzo P2.
- Actas dermo-sifiliograficas.Actas Dermosifiliogr.2016 Sep 9. pii: S0001-7310(16)30285-X. doi: 10.1016/j.ad.2016.07.017. [Epub ahead of print]
- PMID 27622616
- Dermoscopy in General Dermatology: A Practical Overview.
- Errichetti E1, Stinco G2.
- Dermatology and therapy.Dermatol Ther (Heidelb).2016 Sep 9. [Epub ahead of print]
- Over the last few years, dermoscopy has been shown to be a useful tool in assisting the noninvasive diagnosis of various general dermatological disorders. In this article, we sought to provide an up-to-date practical overview on the use of dermoscopy in general dermatology by analysing the dermoscop
- PMID 27613297
Japanese Journal
- Immunohistochemical study of acantholytic squamous cell carcinomas of head and neck region
- 免疫グロブリン大量療法反復投与が有用であった尋常性天疱瘡の1例
- 症例報告 若年女性の下腿に限局して生じたtransient acantholytic dermatosisの1例
- 臨床皮膚科 = Japanese journal of clinical dermatology 69(1), 38-41, 2015-01
- NAID 40020303982
Related Links
- Pemphigus foliaceus: Pemphigus erythematosus · Endemic pemphigus · Paraneoplastic pemphigus · IgA pemphigus (Subcorneal pustular dermatosis · Intraepidermal neutrophilic IgA dermatosis). Other. Transient acantholytic dermatosis ...
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