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1. 細菌性心内膜炎への抗菌薬の予防投与antimicrobial prophylaxis for the prevention of bacterial endocarditis [show details]
…was not examined. Antibiotic trials have examined the impact of antibiotic prophylaxis on bacteremia, but only limited observational data are available on the effect of antibiotic prophylaxis on the risk …
2. β-ラクタム系抗生物質：作用機序、耐性および有害作用beta lactam antibiotics mechanisms of action and resistance and adverse effects [show details]
…autolytic enzymes or have mutations in the regulatory genes; these strains show the phenomenon of "tolerance" to beta-lactam antibiotics, that is, their growth is inhibited by the antibiotic but the bacteria are …
3. 成人における腹腔内感染症に対する抗菌薬によるアプローチantimicrobial approach to intra abdominal infections in adults [show details]
…of different antibiotic regimens with these spectra of activity have generally demonstrated equivalent efficacy . The precise antimicrobial regimen and indications for broader antimicrobial coverage depend …
4. 抗菌薬感受性試験の概要overview of antibacterial susceptibility testing [show details]
…may warrant antimicrobial susceptibility testing. Conventional antimicrobial susceptibility testing methods are phenotypic in vitro tests that provide a direct measurement of antimicrobial activity. These …
5. 嚢胞性線維症：肺疾患治療の概要cystic fibrosis overview of the treatment of lung disease [show details]
… determine if they carry a mutation that makes them eligible for CFTR modulator therapy Selection of the CFTR modulator depends upon the CFTR mutation and the patient age,…development of macrolide-resistant mycobacterial species. If smear-negative patients are subsequently positive by culture, the macrolide should be stopped to avoid induction of macrolide resistance.…