English Journal

Investigation and threshold of optimum blood concentration of voriconazole: a descriptive statistical meta-analysis.

Hamada Y, Seto Y, Yago K, Kuroyama M.SourceDepartment of Pharmacy, Kitasato University East Hospital, 2-1-1, Asamizodai, Minamiku, Sagamihara, Kanagawa, 258-0380, Japan, yuki@kitasato-u.ac.jp.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.J Infect Chemother.2012 Jan 11. [Epub ahead of print]
Voriconazole (VRCZ) reportedly possesses a broad spectrum of antifungal activity against Aspergillus spp. and Candida spp., and the blood concentration of VRCZ is correlated with both the efficacy and the adverse effects of this drug. Monitoring of the blood concentration target level of VRCZ has no
PMID 22231601

Rapid simultaneous determination of voriconazole and its N-oxide in human plasma using an isocratic high-performance liquid chromatography method and its clinical application.

Yamada T, Mino Y, Yagi T, Naito T, Kawakami J.AbstractOBJECTIVES: The aim of this study was to develop a simultaneous determination method for voriconazole (VRCZ) and its N-oxide (VNO) in human plasma and to apply it to clinical samples.
Clinical biochemistry.Clin Biochem.2012 Jan;45(1-2):134-8. Epub 2011 Nov 23.
OBJECTIVES: The aim of this study was to develop a simultaneous determination method for voriconazole (VRCZ) and its N-oxide (VNO) in human plasma and to apply it to clinical samples.DESIGN AND METHODS: Plasma specimens were deproteinized with acetonitrile and then injected into an HPLC-UV system. V
PMID 22138022

Cerebral phaeohyphomycosis: Case report.

Ochiai H, Kawano H, Minato S, Yoneyama T, Shimao Y.SourceDepartments of Neurosurgery Neurology Pathology, Miyazaki Prefectural Hospital, Miyazaki, Japan.
Neuropathology : official journal of the Japanese Society of Neuropathology.Neuropathology.2011 Aug 1. doi: 10.1111/j.1440-1789.2011.01244.x. [Epub ahead of print]
Cerebral phaeohyphomycosis is a rare and frequently fatal disease. This disease is often caused by hematogenous spread of pathogens that are inoculated in the skin of the extremities after slight or minor trauma, and its mortality rate is rather high despite aggressive treatment. Our patient present
PMID 21801237

Japanese Journal

抗真菌薬のPK/PD

三鴨廣繁,山岸由佳
深在性真菌症 7(1), 17-25, 2011-05
NAID 40018867949

Deep Skin Infection of Scedosporium apiospermum in a Patient with Refractory Idiopathic Thrombocytopenic Purpura

Takeuchi Makoto,Yoshida Chikamasa,Ota Yusuke,Fujiwara Yutaka
Internal Medicine 50(12), 1339-1343, 2011
… apiospermum, voriconazole (VRCZ) was administered and prompt improvement was observed. … apiospermum is resistant to amphotericin B, VRCZ should be selected as the first choice of antifungal agent when mold is considered to be the causative organism. …
NAID 130000770503

Intravenous micafungin versus voriconazole for chronic pulmonary aspergillosis: A multicenter trial in Japan.

Kohno Shigeru,Izumikawa Koichi,Ogawa Kenji,Kurashima Atsuyuki,Okimoto Niro,Amitani Ryoichi,Kakeya Hiroshi,Niki Yoshihito,Miyazaki Yoshitsugu
The Journal of infection 61(5), 410-418, 2010-11
… We conducted a randomized, multicenter, open-label trial comparing intravenous micafungin (MCFG) of 150-300 mg once daily with intravenous voriconazole (VRCZ) of 6 mg/kg twice on Day 1 followed by 4 mg/kg twice daily for the treatment of 107 in patients with CPA to compare the efficacy and safety of both drugs as initial treatment in Japan. … The total of 50 and 47 patients were assigned to the MCFG and VRCZ groups, respectively. …
NAID 120002462808

Related Pictures

「VRCZ」)Tocris Bioscience 10MG leviton-vrcz1-1lz-1-button-zone-dimming-z Mensajes positivos en la pared tumblr Leviton HAI VRCZ4-M0Z Vizia Rf+ 4 Zone Leviton VRCZ4-MRZ Vizia RF + 4-Button Zone Sagopa Kajmer Istanbul Çekmeköy Konseri Partido Verde Vrcz (@PVEM_Vrcz) | Twitter