English Journal

Why are the 2-oxoacid dehydrogenase complexes so large? Generation of an active trimeric complex.

Marrott NL1, Marshall JJ2, Svergun DI3, Crennell SJ1, Hough DW1, van den Elsen JM4, Danson MJ1.
The Biochemical journal.Biochem J.2014 Nov 1;463(3):405-12. doi: 10.1042/BJ20140359.
The four-component polypeptides of the 2-oxoacid dehydrogenase complex from the thermophilic archaeon Thermoplasma acidophilum assemble to give an active multienzyme complex possessing activity with the branched-chain 2-oxoacids derived from leucine, isoleucine and valine, and with pyruvate. The dih
PMID 25088564

Structural and biochemical analysis of a type II free methionine-R-sulfoxide reductase from Thermoplasma acidophilum.

Kim HS1, Kwak GH2, Lee K1, Jo CH1, Hwang KY3, Kim HY4.
Archives of biochemistry and biophysics.Arch Biochem Biophys.2014 Oct 15;560:10-9. doi: 10.1016/j.abb.2014.07.009. Epub 2014 Jul 17.
Free methionine-R-sulfoxide reductase (fRMsr) enzymes only reduce the free form of methionine-R-sulfoxide and can be grouped into two types with respect to the number of conserved Cys residues in the active sites. In this work, the crystal structures of type II fRMsr from Thermoplasma acidophilum (T
PMID 25043974

Activation of the MCM helicase from the thermophilic archaeon, Thermoplasma acidophilum by interactions with GINS and Cdc6-2.

Ogino H1, Ishino S, Haugland GT, Birkeland NK, Kohda D, Ishino Y.
Extremophiles : life under extreme conditions.Extremophiles.2014 Sep;18(5):915-24. doi: 10.1007/s00792-014-0673-6. Epub 2014 Aug 9.
In DNA replication studies, the mechanism for regulation of the various steps from initiation to elongation is a crucial subject to understand cell cycle control. The eukaryotic minichromosome maintenance (MCM) protein complex is recruited to the replication origin by Cdc6 and Cdt1 to form the pre-r
PMID 25107272

Japanese Journal

Variation in Molecular Species of Core Lipids from the Order Thermoplasmales Strains Depends on the Growth Temperature

Uda Ikuko,Sugai Akihiko,Itoh Yuko H. [他],ITOH Toshihiro
Journal of oleo science 53(8), 399-404, 2004-08-01
… The core lipids from five strains of the order Thermoplasmales grown at various temperatures have been investigated. …
NAID 10013338582