新生児一過性多呼吸 transient tachypnea of the newborn = TTN
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- 《略》 teetotal; teetotaller; tuberculin-tested
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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2017/07/22 20:43:57」(JST)
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| Transient tachypnea of the newborn |
| Classification and external resources |
| Specialty |
pediatrics |
| ICD-10 |
P22.1 |
| ICD-9-CM |
770.6 |
| DiseasesDB |
32373 |
| MedlinePlus |
007233 |
| eMedicine |
ped/2597 radio/710 |
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[edit on Wikidata]
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Transient tachypnea of the newborn (TTN, TTNB, or "transitory tachypnea of newborn") is a respiratory problem that can be seen in the newborn shortly after delivery. Amongst causes of respiratory distress in term neonates, it is the most common.[1][2] It consists of a period of rapid breathing (higher than the normal range of 30-60 times per minute). It is likely due to retained lung fluid. It is most often seen in 35+ week gestation babies who are delivered by caesarian section without labor. Usually, this condition resolves over 24–48 hours. Treatment is supportive and may include supplemental oxygen and antibiotics. The chest x-ray shows hyperinflation of the lungs including prominent pulmonary vascular markings, flattening of the diaphragm, and fluid in the horizontal fissure of the right lung.
Pathophysiology
- Due to the higher incidence of TTN in newborns delivered by caesarean section, it has been postulated that TTN could result from a delayed absorption of fetal lung fluid from the pulmonary lymphatic system. The increased fluid in the lungs leads to increased airway resistance and reduced lung compliance. It is thought this could be from lower levels of circulating catecholamines after a caesarean section, which are believed to be necessary to alter the function of the ENaC channel to absorb excess fluid from the lungs.
- Pulmonary immaturity has also been proposed as a causative factor. Levels of phosphatidylglycerol (an indicator of lung maturity) were found to be negative in certain newborns.
- Mild surfactant deficiency has also been suggested as a causative factor.
Clinical evaluation
TTN is a diagnosis of exclusion as it is a benign condition that can have symptoms and signs similar to more serious conditions, such as respiratory distress syndrome.[1] A chest X-ray may show a radiopaque line - fluid - in the horizontal fissure of the right lung, fluid infiltrate throughout alveoli or fluid in individual lung lobes.[1]
References
- ^ a b c Lissauer T, Clayden,(2007). Illustrated textbook of paediatrics (3rd ed.). Mosby/Elsevier. p. 162. ISBN 0-7234-3397-6
- ^ Hermansen CL, Lorah KN (October 2007). "Respiratory distress in the newborn". Am Fam Physician. 76 (7): 987–94. PMID 17956068.
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Certain conditions originating in the perinatal period / fetal disease (P, 760–779)
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Maternal factors and
complications of pregnancy,
labour and delivery |
| placenta: |
- Placenta praevia
- Placental insufficiency
- Twin-to-twin transfusion syndrome
|
| chorion/amnion: |
|
| umbilical cord: |
- Umbilical cord prolapse
- Nuchal cord
- Single umbilical artery
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Length of gestation
and fetal growth |
- Small for gestational age/Large for gestational age
- Preterm birth/Postmature birth
- Intrauterine growth restriction
|
| Birth trauma |
- scalp
- Cephalhematoma
- Chignon
- Caput succedaneum
- Subgaleal hemorrhage
- Brachial plexus lesion
- Erb's palsy
- Klumpke paralysis
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| By system |
| Respiratory |
- Intrauterine hypoxia
- Infant respiratory distress syndrome
- Transient tachypnea of the newborn
- Meconium aspiration syndrome
- pleural disease
- Pneumothorax
- Pneumomediastinum
- Wilson–Mikity syndrome
- Bronchopulmonary dysplasia
|
| Cardiovascular |
- Pneumopericardium
- Persistent fetal circulation
|
Haemorrhagic and
hematologic disease |
- Vitamin K deficiency
- Haemorrhagic disease of the newborn
- HDN
- ABO
- Anti-Kell
- Rh c
- Rh D
- Rh E
- Hydrops fetalis
- Hyperbilirubinemia
- Kernicterus
- Neonatal jaundice
- Velamentous cord insertion
- Intraventricular hemorrhage
- Germinal matrix hemorrhage
- Anemia of prematurity
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| Digestive |
- Ileus
- Necrotizing enterocolitis
- Meconium peritonitis
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Integument and
thermoregulation |
- Erythema toxicum
- Sclerema neonatorum
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| Nervous system |
- Periventricular leukomalacia
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| Musculoskeletal |
- Gray baby syndrome
- muscle tone
- Congenital hypertonia
- Congenital hypotonia
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|
| Infectious |
- Vertically transmitted infection
- Neonatal infection
- Congenital rubella syndrome
- Neonatal herpes simplex
- Mycoplasma hominis infection
- Ureaplasma urealyticum infection
- Omphalitis
- Neonatal sepsis
- Group B streptococcal infection
- Neonatal conjunctivitis
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| Other |
- Miscarriage
- Perinatal mortality
- Stillbirth
- Infant mortality
- Neonatal withdrawal
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UpToDate Contents
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English Journal
- The role of VATS in the staging of non small cell lung cancer.
- Bagheri R, Tavassoli A, Haghi SZ, Sahebi MA, Bigdeli N.SourceDepartment of Thoracic Surgery, Cardiothoracic Surgery and Transplant Research Center, Imam Reza Hospital, Mashhad, Iran.
- Lung India : official organ of Indian Chest Society.Lung India.2013 Jan;30(1):12-5. doi: 10.4103/0970-2113.106120.
- INTRODUCTION: Since determining of prognosis and treatment method is related to accurate evaluation of TNM staging of non small cell lung cancer (NSCLC), we aimed to evaluate the role of Video-assisted thoracic surgery (VATS) in staging of NSCLC.MATERIALS AND METHODS: This study was performed on 40
- PMID 23661910
- Transthoracic needle biopsy.
- Birchard KR.SourceDepartment of Radiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
- Seminars in interventional radiology.Semin Intervent Radiol.2011 Mar;28(1):87-97. doi: 10.1055/s-0031-1273943.
- Transthoracic needle biopsy (TTNB) is integral in the diagnosis and treatment of many thoracic diseases, and is an important alternative to more invasive surgical procedures. Both computed tomography and ultrasound may be used as imaging guidance for TTNB, with CT being more commonly utilized. Needl
- PMID 22379279
- Chest computed tomography (CT) immediately after CT-guided transthoracic needle aspiration biopsy as a predictor of overt pneumothorax.
- Noh TJ, Lee CH, Kang YA, Kwon SY, Yoon HI, Kim TJ, Lee KW, Lee JH, Lee CT.SourceDivision of Pulmonology and Critical Care Medicine, Department of Internal Medicine and Lung Institute, Seoul National University College of Medicine, Seoul, Korea.
- The Korean journal of internal medicine.Korean J Intern Med.2009 Dec;24(4):343-9. doi: 10.3904/kjim.2009.24.4.343. Epub 2009 Nov 27.
- BACKGROUND/AIMS: This study examined the correlation between pneumothorax detected by immediate post-transthoracic needle aspiration-biopsy (TTNB) chest computed tomography (CT) and overt pneumothorax detected by chest PA, and investigated factors that might influence the correlation.METHODS: Adult
- PMID 19949733
Japanese Journal
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新生児一過性多呼吸, transient tachypnea of the newborn