同: transient lower esophageal sphincter relaxation

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1. 逆流性食道炎の病態生理 pathophysiology of reflux esophagitis
2. 非酸逆流の臨床症状、診断、および治療 clinical manifestations diagnosis and treatment of non acid reflux
3. コレシストキニンの生理学 physiology of cholecystokinin
4. 胃食道逆流症のためのラジオ波焼灼治療 radiofrequency treatment for gastroesophageal reflux disease
5. 裂孔ヘルニア hiatus hernia

English Journal

Intra-bolus pressure and esophagogastric gradient, assessed with high-resolution manometry, are associated with acid exposure and proximal migration of refluxate.

Ribolsi M1, Balestrieri P1, Holloway RH2,3, Emerenziani S1, Cicala M1.
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus / I.S.D.E.Dis Esophagus.2015 Nov 6. doi: 10.1111/dote.12434. [Epub ahead of print]
Trans-sphincteric pressure gradient (TSPG) seems to play a relevant role in eliciting refluxes during transient lower esophageal sphincter relaxations (TLESRs). Intra-bolus pressure (IBP) is considered to be correlated to esophageal wall tone. We aimed to evaluate the relationship between IBP, TSPG
PMID 26542165

Circular and longitudinal muscles shortening indicates sliding patterns during peristalsis and transient lower esophageal sphincter relaxation.

Patel N1, Jiang Y1, Mittal RK2, Kim TH1, Ledgerwood M1, Bhargava V3.
American journal of physiology. Gastrointestinal and liver physiology.Am J Physiol Gastrointest Liver Physiol.2015 Sep 1;309(5):G360-7. doi: 10.1152/ajpgi.00067.2015. Epub 2015 Jun 4.
Esophageal axial shortening is caused by longitudinal muscle (LM) contraction, but circular muscle (CM) may also contribute to axial shortening because of its spiral morphology. The goal of our study was to show patterns of contraction of CM and LM layers during peristalsis and transient lower esoph
PMID 26045610

[Pathophysiology and treatment of reflux esophagitis].

Iwakiri K, Kawami N.
Nihon rinsho. Japanese journal of clinical medicine.Nihon Rinsho.2015 Jul;73(7):1098-102.
Reflux esophagitis (RE) is characterized by excessive esophageal acid exposure. The number of acid reflux episodes, the way acid comes up after reflux and the delay of acid bolus clearance cause excessive esophageal acid exposure. Transient lower esophageal sphincter relaxation (TLESR) is the major
PMID 26165064

Japanese Journal

胃・食道逆流症(GERD)の臨床

遠藤光夫
日本内科学会雑誌 89(1), 1-2, 2000-01-10
NAID 10005520597

臨床経過中に重症の逆流性食道炎を合併した神経性食欲不振症の1例

芝山幸久,滝井英治,加藤明子,松村純子,島田涼子,坪井康次,中野弘一,筒井末春
心身医学 39(7), 547-551, 1999-10-01
… 発症機序として, 低栄養状態に伴う胃排出能低下によりTLESRが増加し, 逆流性食道炎を発症したと考えられた. …
NAID 110001122390

Related Pictures

TLESR → reflux and inflammation PHARMACEUTICAL CARE WHEN DISPENSING OTC Terminating motor events for TLESR are esophageal sphincter relaxation (TLESR High-resolution Manometry: Esophageal image tlesr for term side of card Specific Movement of Esophagus During