サネカズラ、(生薬)南五味子

English Journal

Jiang K1, Song QY1, Peng SJ1, Zhao QQ1, Li GD1, Li Y2, Gao K3.
Fitoterapia.Fitoterapia.2015 Jun;103:63-70. doi: 10.1016/j.fitote.2015.03.015. Epub 2015 Mar 19.
Nine new lignans (1-8, 13) and five known ones (9-12, 14) have been isolated from the roots of Schisandra sphenanthera and were tested for their capacity to scavenge 2,2-diphenyl-1-Picryl-hydrazyl (DPPH). Of these lignans tested, compounds 1, 7, 8 and 13 exhibited noteworthy antioxidant activity wit
PMID 25796351

Protective effect of Wuzhi tablet (Schisandra sphenanthera extract) against cisplatin-induced nephrotoxicity via Nrf2-mediated defense response.

Jin J1, Li M1, Zhao Z2, Sun X1, Li J3, Wang W1, Huang M1, Huang Z4.
Phytomedicine : international journal of phytotherapy and phytopharmacology.Phytomedicine.2015 May 15;22(5):528-35. doi: 10.1016/j.phymed.2015.03.003. Epub 2015 Mar 20.
Cisplatin is a potent anti-cancer agent for various types of tumors. However, the clinical use of cisplatin is often limited by its nephrotoxicity. This study reports that WZ tablet (WZ, a preparation of an ethanol extract of Schisandra sphenanthera) mitigates cisplatin-induced toxicity in renal epi
PMID 25981918

Therapeutic efficacy of Wuzhi tablet (Schisandra sphenanthera Extract) on acetaminophen-induced hepatotoxicity through a mechanism distinct from N-acetylcysteine.

Fan X1, Chen P1, Jiang Y1, Wang Y1, Tan H1, Zeng H1, Wang Y1, Qu A1, Gonzalez FJ1, Huang M1, Bi H2.
Drug metabolism and disposition: the biological fate of chemicals.Drug Metab Dispos.2015 Mar;43(3):317-24. doi: 10.1124/dmd.114.062067. Epub 2014 Dec 22.
Acetaminophen (APAP) hepatotoxicity is the most common cause of drug-induced liver injury and N-acetylcysteine (NAC) is the primary antidote of APAP poisoning. Wuzhi tablet (WZ), the active constituents well identified and quantified, is a preparation of an ethanol extract of Schisandra sphenanthera
PMID 25534769

Japanese Journal

Schisphenlignans A?E : Five New Dibenzocyclooctadiene Lignans from Schisandra sphenanthera

李華,菊地良栄,熊谷昌則,天野敏男,藤原一彦,林金明,小川信明
分析化学 = Japan analyst 60(10), 813-817, 2011-10-05
… A Schisandra chinensis and Schisandra sphenanthera were distinguished by the score plots of PC3 vs. PC1 of principal component analysis (PCA) of the near infrared (NIR) spectra. … The four producing districts of Schisandra chinensis were also distinguished by the score plots of PC1 vs. PC2 of NIR data. …
NAID 10029482389