English Journal

Rescue of Aspergillus nidulans severely debilitating null mutations in ESCRT-0, I, II and III genes by inactivation of a salt-tolerance pathway allows examination of ESCRT gene roles in pH signalling.

Calcagno-Pizarelli AM, Hervás-Aguilar A, Galindo A, Abenza JF, Peñalva MA, Arst HN Jr.SourceSection of Microbiology, Imperial College London, Flowers Building, Armstrong Road, London SW7 2AZ, UK.
Journal of cell science.J Cell Sci.2011 Dec 1;124(Pt 23):4064-76. doi: 10.1242/jcs.088344. Epub 2011 Dec 1.
The Aspergillus pal pathway hijacks ESCRT proteins into ambient pH signalling complexes. We show that components of ESCRT-0, ESCRT-I, ESCRT-II and ESCRT-III are nearly essential for growth, precluding assessment of null mutants for pH signalling or trafficking. This severely debilitating effect is r
PMID 22135362

Therapeutic application of 6-Hz-primed low-frequency rTMS combined with intensive speech therapy for post-stroke aphasia.

Kakuda W, Abo M, Momosaki R, Morooka A.SourceDepartment of Rehabilitation Medicine, Jikei University School of Medicine, Tokyo, Japan.
Brain injury : [BI].Brain Inj.2011;25(12):1242-8. doi: 10.3109/02699052.2011.608212. Epub 2011 Sep 8.
OBJECTIVE: To clarify the safety, feasibility and efficacy of 6-Hz-primed low-frequency repetitive transcranial magnetic stimulation (rTMS) combined with intensive speech therapy (ST) for post-stroke aphasic patients.METHODS: Four adult patients with history of left hemispheric stroke and with motor
PMID 21902549

Japanese Journal

安保雅博
脳神経外科ジャーナル 21(7), 527-533, 2012-07-20
最近,反復低頻度経頭蓋磁気刺激療法が失語症の治療として用いられてきた.そのほとんどが右大脳半球に対してである.われわれは,機能的MRIを使用してどちらの半球が主体となって失語症の改善に対して重要な役割をはたしているかを判断し,経頭蓋磁気刺激の左右打ち分けを世界に先駆けて行っている.また,運動性優位の失語ならばIFGに,感覚性優位の失語ならSTGに反復経頭蓋磁気刺激を施行している.脳卒中による20名 …
NAID 110009477213