関: Bartonella henselae

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/03/16 17:44:56」(JST)

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Bartonella henselae, formerly Rochalimæa, is a proteobacterium that can cause bacteremia, endocarditis, bacillary angiomatosis, and peliosis hepatis. It is also the causative agent of cat-scratch disease^[1] (bartonellosis) which, as the name suggests, occurs after a cat bite or scratch. The disease is characterized by lymphadenopathy (swelling of the lymph nodes) and fever.

Peliosis hepatis caused by B. henselae can occur alone or develop with cutaneous bacillary angiomatosis or bacteremia. Patients with peliosis hepatis present with gastrointestinal symptoms, fever, chills, and an enlarged liver and spleen containing blood-filled cavities. This systemic disease is mostly seen in patients infected with HIV and other immunocompromised individuals.

Bartonella henselae is a member of the class of the Bartonella genus, one of the most common types of bacteria in the world. It infects the host cell by sticking to it using the Trimeric Autotransporter Adhesins (TAA).

The presence of bacteria can be detected by a special stain called Warthin-Starry stain, or by a similar silver stain technique performed on infected tissue.

Diagnosis

Bartonella henselae is gram negative rod or bacillus with a polar flagellum. Bartonella henselae can be cultured in a lysis-centrifugation blood culture. The diagnosis is made after a detailed patient history and physical is taken. A hallmark of the infectious process include history of contact with a cat (hence the name cat scratch disease).

Symptoms

Common symptoms:^[2]

Fever
Enlarged, tender lymph nodes that develop 1–3 weeks after exposure
A papule or pustule at the inoculation site

Treatment

Bartonella henselae (cat scratch disease) infections are usually self-limiting, but can be treated with azithromycin, doxycycline.^[3]

References

^ Jerris RC, Regnery RL (1996). "Will the real agent of cat-scratch disease please stand up?". Annu. Rev. Microbiol. 50: 707–25. doi:10.1146/annurev.micro.50.1.707. PMID 8905096.
^ "Bartonella Infection (Cat Scratch Disease, Trench Fever, and Carrión’s Disease)". Centers for Disease Control and Prevention. 29 November 2012.
^ Bartonellosis~treatment at eMedicine

External Links

"Bartonella henselae". NCBI Taxonomy Browser. 38323.

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1. ネコ引っかき病の微生物学、疫学、臨床症状、および診断 microbiology epidemiology clinical manifestations and diagnosis of cat scratch disease
2. ネコ引っかき病の治療 treatment of cat scratch disease
3. HIV感染患者におけるバルトネラ感染症の疫学および臨床症状 epidemiology and clinical manifestations of bartonella infections in hiv infected patients
4. バルトネラによる心内膜炎 endocarditis caused by bartonella
5. バルトネラ属の基礎生物学 basic biology of bartonella species

English Journal

Bartonella clarridgeiae and Bartonella vinsonii subsp. berkhoffii exposure in captive wild canids in Brazil.

Fleischman DA1, Chomel BB1, Kasten RW1, André MR2, Gonçalves LR2, Machado RZ2.
Epidemiology and infection.Epidemiol Infect.2015 Feb;143(3):573-7. doi: 10.1017/S0950268814001277. Epub 2014 Jun 3.
SUMMARY Wild canids are potential hosts for numerous species of Bartonella, yet little research has been done to quantify their infection rates in South America. We sought to investigate Bartonella seroprevalence in captive wild canids from 19 zoos in São Paulo and Mato Grosso states, Brazil. Blood
PMID 24892580

Concurrent Bartonella henselae infection in a dog with panniculitis and owner with ulcerated nodular skin lesions.

Rossi MA1, Balakrishnan N, Linder KE, Messa JB, Breitschwerdt EB.
Veterinary dermatology.Vet Dermatol.2015 Feb;26(1):60-e22. doi: 10.1111/vde.12174. Epub 2014 Oct 8.
BACKGROUND: Bartonella henselae, a Gram-negative, zoonotic Alphaproteobacteria that infects erythrocytes, endothelial cells and dendritic cells, has previously been implicated as a cause of panniculitis in dogs and a human.ANIMAL AND OWNER: An 8-year-old, spayed female Labrador retriever and its 78-
PMID 25292107

Prevalence of select vector-borne pathogens in stray and client-owned dogs from Algiers.

Azzag N1, Petit E2, Gandoin C3, Bouillin C3, Ghalmi F1, Haddad N3, Boulouis HJ4.
Comparative immunology, microbiology and infectious diseases.Comp Immunol Microbiol Infect Dis.2015 Jan 14. pii: S0147-9571(15)00002-8. doi: 10.1016/j.cimid.2015.01.001. [Epub ahead of print]
Data on the prevalence of vector-borne diseases agents infecting canines in Algeria is currently lacking. The purpose of this study is to assess by serological and molecular methods the prevalence of select arthropod borne-bacterial infections in client-owned and stray dogs. Antibodies to Anaplasma
PMID 25638478

Japanese Journal

人と動物の Bartonella 感染症 : 猫ひっかき病を中心として

丸山総一,壁谷英則,見上彪
日本獣医師会雑誌 = Journal of the Japan Veterinary Medical Association 56(4), 209-217, 2003-04-20
… 1990年代の米国において、猫が感染源となってAIDS患者に発生した特殊な血管増殖性疾病から新種の細菌Bartonella henselae(当時はRochalimaea henselae)が分離されたことが契機となって、本菌がCSDの主要な病原体であることが明らかとなった。 …
NAID 120004560465

猫ひっかき病の治療経験

西口雅彦,小田純爾,矢野勝巳,鳥越雄史
整形外科と災害外科 47(1), 354-356, 1998-03-25
We treated two cases of Cat Scratch Disease (CSD), and investigated the following factors: (1) laboratory parameters, (2) imaging evaluation using MRI, (3) pathological examination, (4) bacterial cult …
NAID 10011356255

「ロシャリメア・ヘンセラ」

Bartolae
Scientific classification
Kingdom:	Bacteria
Phylum:	Proteobacteria
Class:	Alphaproteobacteria
Order:	Rhizobiales
Family:	Bartonellaceae
Genus:	Bartonella
Species:	B. henselae
Binomial name
	Bartonella henselae; (Regnery et al. 1992)