- 関
- iohexol
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/12/21 06:23:30」(JST)
wiki en
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
- 1. 造影剤に対する即時型過敏反応：臨床症状、診断、および治療 immediate hypersensitivity reactions to radiocontrast media clinical manifestations diagnosis and treatment
- 2. 造影剤誘発性腎症の予防 prevention of contrast induced nephropathy
- 3. 腎機能の評価 assessment of kidney function
- 4. 造影剤に対する即時型過敏反応：再発反応の予防 immediate hypersensitivity reactions to radiocontrast media prevention of recurrent reactions
- 5. 造影剤誘発性腎症の病因、臨床的特徴、および診断 pathogenesis clinical features and diagnosis of contrast induced nephropathy
English Journal
- Classification of structurally related commercial contrast media by near infrared spectroscopy.
- Yip WL1, Soosainather TC2, Dyrstad K3, Sande SA4.Author information 1University of Oslo, School of Pharmacy, Department of Pharmacy, P.O. Box 1068, Blindern, N-0316 Oslo, Norway. Electronic address: w.l.yip@farmasi.uio.no.2GE Healthcare, Nycoveien 1, P.O. Box 4220, 0401 Oslo, Norway.3University of Oslo, School of Pharmacy, Department of Pharmacy, P.O. Box 1068, Blindern, N-0316 Oslo, Norway; KD Metrix, Spireaveien 10A, 0580 Oslo, Norway.4University of Oslo, School of Pharmacy, Department of Pharmacy, P.O. Box 1068, Blindern, N-0316 Oslo, Norway.AbstractNear infrared spectroscopy (NIRS) is a non-destructive measurement technique with broad application in pharmaceutical industry. Correct identification of pharmaceutical ingredients is an important task for quality control. Failure in this step can result in several adverse consequences, varied from economic loss to negative impact on patient safety. We have compared different methods in classification of a set of commercially available structurally related contrast media, Iodixanol (Visipaque(®)), Iohexol (Omnipaque(®)), Caldiamide Sodium and Gadodiamide (Omniscan(®)), by using NIR spectroscopy. The performance of classification models developed by soft independent modelling of class analogy (SIMCA), partial least squares discriminant analysis (PLS-DA) and Main and Interactions of Individual Principal Components Regression (MIPCR) were compared. Different variable selection methods were applied to optimize the classification models. Models developed by backward variable elimination partial least squares regression (BVE-PLS) and MIPCR were found to be most effective for classification of the set of contrast media. Below 1.5% of samples from the independent test set were not recognized by the BVE-PLS and MIPCR models, compared to up to 15% when models developed by other techniques were applied.
- Journal of pharmaceutical and biomedical analysis.J Pharm Biomed Anal.2014 Mar;90:148-60. doi: 10.1016/j.jpba.2013.11.033. Epub 2013 Dec 7.
- Near infrared spectroscopy (NIRS) is a non-destructive measurement technique with broad application in pharmaceutical industry. Correct identification of pharmaceutical ingredients is an important task for quality control. Failure in this step can result in several adverse consequences, varied from
- PMID 24374816
- Methods of assessing renal function.
- Filler G, Yasin A, Medeiros M.Author information Department of Pediatrics, Children's Hospital, London Health Science Centre, University of Western Ontario, 800 Commissioners Road East, London, Ontario, Canada, N6A 5W9, guido.filler@lhsc.on.ca.AbstractAccurate assessment of renal function is critical for appropriate drug dosing of renally excreted compounds. Glomerular filtration rate (GFR) is considered the best marker of kidney function. Inulin clearance forms the gold standard for measuring GFR, both in adults and in children. The method is invasive, cumbersome, and smaller children require urinary catheterization for accurate timed urine collections. Nuclear medicine methods replaced inulin clearance in the 1970s after (51)Cr EDTA clearance was introduced. Inulin has no plasma protein binding, whereas all commonly used radioisotopes have a small amount of plasma protein binding that leads to lower values. Only iohexol does not have significant plasma protein binding. The underestimation due to plasma protein binding is partially offset by overestimation due to the use of non-compartmental pharmacokinetic modeling of the plasma disappearance of the radioisotope. The problem could be overcome with a urinary nuclear medicine clearance method, but these have not been validated in children. Endogenous markers of GFR include serum creatinine and low molecular weight proteins such as cystatin C and beta-trace protein. Of these, estimation of GFR using cystatin C appears to be the most promising, although its accuracy in pregnancy and in the neonatal period may be limited.
- Pediatric nephrology (Berlin, Germany).Pediatr Nephrol.2014 Feb;29(2):183-92. doi: 10.1007/s00467-013-2426-7. Epub 2013 Feb 17.
- Accurate assessment of renal function is critical for appropriate drug dosing of renally excreted compounds. Glomerular filtration rate (GFR) is considered the best marker of kidney function. Inulin clearance forms the gold standard for measuring GFR, both in adults and in children. The method is in
- PMID 23417278
- Iodinated contrast does not alter clotting dynamics in acute ischemic stroke as measured by thromboelastography.
- McDonald MM, Archeval-Lao JM, Cai C, Peng H, Sangha N, Parker SA, Wetzel J, Riney SA, Cherches MF, Guthrie GJ, Roper TC, Kawano-Castillo JF, Pandurengan R, Rahbar MH, Grotta JC.Author information From the Department of Neurology, University of Texas Medical School at Houston, Houston, TX.AbstractBACKGROUND AND PURPOSE: Iodinated contrast agents used for computed tomography angiography (CTA) may alter fibrin fiber characteristics and decrease fibrinolysis by tissue plasminogen activator (tPA). Thromboelastography (TEG) measures the dynamics of coagulation and correlates with thrombolysis in acute ischemic stroke patients. We hypothesized that receiving CTA before tPA will not impair thrombolysis as measured by TEG.
- Stroke; a journal of cerebral circulation.Stroke.2014 Feb;45(2):462-6. doi: 10.1161/STROKEAHA.113.003268. Epub 2013 Dec 26.
- BACKGROUND AND PURPOSE: Iodinated contrast agents used for computed tomography angiography (CTA) may alter fibrin fiber characteristics and decrease fibrinolysis by tissue plasminogen activator (tPA). Thromboelastography (TEG) measures the dynamics of coagulation and correlates with thrombolysis in
- PMID 24370757
Japanese Journal
- デザイン心理学を活用したオムニパークシリンジのラベルデザイン開発 (特集 第52回全日本包装技術研究大会優秀発表)
- 安東 幸弘,片山 通博,日比野 治雄 [他]
- 包装技術 53(3), 264-267, 2015-03
- NAID 40020383008
- 顎顔面領域のＣＴ‐Ａｎｇｉｏｇｒａｐｈｙにおける造影並びに撮像条件 血管並びに腫ようの同時描出のための１相法の検討:血管並びに腫瘍の同時描出のための1相法の検討
- 森田 康彦,犬童 寛子,野井倉 武憲
- 歯科放射線 39(3), 159-167, 1999
- … A total amount of 100ml nonionic contrast media (Omnipaque 240, 240mg iodine per milliliter, Daiichi seiyaku, Tokyo, Japan) was injected intravenously with a flow of 1.5ml/sec. …
- NAID 130003919204
- ウサギ顎関節下関節腔における造影剤イオヘキソール灌流後の滑膜表面の変化に関する走査型電子顕微鏡的研究
- 水谷 太尊,山口 晃,西村 恒一
- 日本口腔外科学会雑誌 41(10), 845-857, 1995-10-20
- … Next, the inferior articular cavity was perfused with physiological saline solution and iohexol (Omnipaque<SUP>®</SUP>300) as contrast medium by a puncture procedure established in this study, and changes in the synovial surface anterior to the inferior articular cavity were observed by SEM.<BR>1. …
- NAID 10006384154
Related Links
- OMNIPAQUE 300 and OMNIPAQUE 350 have osmolalities from approximately 2.2 to 3.0 times that of plasma (285 mOsm/kg water) or cerebrospinal fluid (301 mOsm/kg water) as shown in the above table and are hypertonic under ...
- Omnipaque is a low-osmolar, nonionic, contrast medium with a broad range of indications, for example intravascular diagnostic procedures such as coronary angiography, spinal cord imaging, and body cavity procedures including ...
Related Pictures
★リンクテーブル★
| リンク元 | 「iohexol」「オムニパーク」 |