WordNet

notch a surface to record something
a V-shaped indentation; "mandibular notch"
a small cut (同)nick, snick
a V-shaped or U-shaped indentation carved or scratched into a surface; "there were four notches in the handle of his revolver"
cut or make a notch into; "notch the rope"

PrepTutorEJDIC

(V字形の)刻み目 / 《米》山あい / 《話》段階(STEP),等級(degree) / …‘に'刻み目をつける / 《話》〈競技の得殿など〉'を'記録する,〈勝利〉'を'収める

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/11/23 23:10:50」(JST)

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Effects of Srxn1 on growth and Notch signalling of astrocyte induced by hydrogen peroxide.

Li L, Lin G, Gu H, Yu L, Ni C.
Artificial cells, nanomedicine, and biotechnology. 2019 Dec;47(1)1917-1923.
To investigate the effect of Sulfiredoxin-1 (Srxn1) on astrocyte injury induced by hydrogen peroxide (HO). Observing the changes of HO on contents of lactate dehydrogenase (LDH), malondialdehyde (MDA), superoxide dismutase (SOD) and apoptosis after transfected Srxn1 siRNA into astrocytes. The protei
PMID 31079497

The Notch signal mediates macrophage polarization by regulating miR-125a/miR-99b expression.

Li Q, He X, Yu Q, Wu Y, Du M, Chen J, Peng F, Zhang W, Chen J, Wang Y, Chen H, Wang H, He D, Wang Q.
Artificial cells, nanomedicine, and biotechnology. 2019 Dec;47(1)833-843.
We aimed to explore the mediating role of Notch signal in macrophage polarization. This signal was knocked out from macrophages of Lyz2 cre and RBP-J flox mice. Bone marrow-derived macrophages (BMDMs) were isolated and polarized. The expressions of polarization markers in BMDMs 24 h after transfec
PMID 30862190

pH sensitive peptide functionalized nanoparticles for co-delivery of erlotinib and DAPT to restrict the progress of triple negative breast cancer.

Wan X, Liu C, Lin Y, Fu J, Lu G, Lu Z.
Drug delivery. 2019 Dec;26(1)470-480.
Although a variety of drug delivery strategies have been designed for enhancing the treatment of Triple negative breast cancer (TNBC), combating with TNBCs is still dramatically challenged by the selection of appropriate therapeutic targets and insufficient tumor accumulation or inner penetration of
PMID 30957572